Results 201 to 210 of about 3,196,403 (286)

Sample Preparation for Multi‐Omics Analysis: Considerations and Guidance for Identifying the Ideal Workflow

PROTEOMICS, EarlyView.
ABSTRACT Advances in methodologies and technologies over the past decade have led to an unprecedented depth of analysis of a cell's biomolecules, with entire genomes able to be sequenced in hours and up to 10,000 transcripts or ORF products (proteins) able to be quantified from a single cell.
Breyer Woodland, Luke A. Farrell, Lana Brockbals, Maria Rezcallah, Aiden Brennan, Emily J. Sunnucks, Sam T. Gould, Aleksandra M. Stanczak, Matthew B. O'Rourke, Matthew P. Padula   +9 more
wiley   +1 more source

Role of glutathione in cellular resistance to alkylating agents

, 1993
O. Michael Colvin, Henry S. Friedman, Michael P. Gamcsik, Catherine Fenselau, John Hilton   +4 more
openalex   +1 more source

Bendamustine (Treanda) Displays a Distinct Pattern of Cytotoxicity and Unique Mechanistic Features Compared with Other Alkylating Agents

Clinical Cancer Research, 2008
L. Leoni, Brandi Bailey, Jack Reifert, H. Bendall, R. Zeller, J. Corbeil, G. Elliott, C. Niemeyer   +7 more
semanticscholar   +1 more source

Proteomic Analysis of Bone Marrow CD138+ Cells to Identify Proteins Associated With the Response of Multiple Myeloma Patients to Commonly Used Therapeutic Regimens

PROTEOMICS, EarlyView.
ABSTRACT Multiple myeloma (MM) remains incurable; gaps in our understanding of MM molecular pathogenesis and drugs’ resistance mechanisms are involved in the failure of therapies. This study aims to identify proteins significantly impacting MM patients’ response to commonly used therapeutic regimens.
Foteini Paradeisi, Aggeliki Tserga, Vasiliki Lygirou, Manousos Makridakis, Rafael Stroggilos, Grigoris Georgiou, George M. Spyrou, Ioannis V. Kostopoulos, Christine‐Ivy Liacos, Aikaterini Termentzi, Meletios A. Dimopoulos, Ourania Tsitsilonis, Antonia Vlahou, Efstathios Kastritis, Jerome Zoidakis   +14 more
wiley   +1 more source

Mechanisms of Chemoresistance to Alkylating Agents in Malignant Glioma

Clinical Cancer Research, 2008
J. Sarkaria, G. Kitange, C. James, R. Plummer, H. Calvert, M. Weller, W. Wick   +6 more
semanticscholar   +1 more source

Recent Advances in Polyimine Chemistry: Synthesis, Functional Design, and Degradation

Journal of Polymer Science, EarlyView.
Conjugated polymers face sustainability challenges amid rising plastic waste. This perspective explores recent efforts in synthesizing CN bond‐containing polymers, emphasizing their degradability and technological implications. Polyimines emerge as promising candidates for recyclable, stimuli‐responsive materials, with potential applications in ...
Debsena Chakraborty, Alex J. Plajer
wiley   +1 more source

Case Studies of Orphan Domain Reclassification in ECOD by Expert Curation

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Homology‐based protein domain classification is a powerful tool for gaining biological insights into protein function. This classification process has been significantly enhanced by the availability of experimental structures and high‐accuracy structural models generated by advanced tools such as AlphaFold.
Jimin Pei, R. Dustin Schaeffer, Qian Cong, Nick V. Grishin   +3 more
wiley   +1 more source

Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents

, 1999
Mark J. Hickman, Leona D. Samson
openalex   +1 more source

A Multipotent Precursor Approach for the Preparation of High‐Molecular Weight Conjugated Polymers with Redox Active Units

Small Methods, EarlyView.
A versatile precursor approach enables the synthesis of high‐molecular‐weight conjugated polymers with tunable electronic properties from a single dihydroanthracene‐based scaffold. Post‐polymerization transformations afford distinct materials incorporating anthracene or anthraquinone units.
Benedetta Bertoncini, Andrea Taddeucci, Sabrina Trano, Sofia Raviolo, Ilaria Valdrighi, Federico Maria Vivaldi, Virgilio Mattoli, Federico Bella, Marco Carlotti   +8 more
wiley   +1 more source

Coupling of S@aerogel and Si/SiOx Nanospheres Electrodes with “Polysulfide” Salt‐Free Electrolytes in a Fluorine‐Free Lithium‐Ion Batteries

Small Structures, EarlyView.
Polysulfide‐based lithium salt and low‐flammable organic solvent are used to synthesize electrolytic solution suitable for building long‐life and fluorine‐free lithium‐ion batteries with improved efficiency, reduced costs, and enhanced safety. Li‐ion batteries play a pivotal role in powering electric vehicles and storing renewable energy.
Marco Agostini, Jang‐Yeon Hwang, Piotr Jankowski, Hyeona Park, Chaiwon Lee, Hansu Kim, Shizhao Xiong, Carmen Cavallo, Arcangelo Celeste, Sang‐Gil Woo, Jinhua Sun, Sergio Brutti, Yang‐Kook Sun, Aleksandar Matic   +13 more
wiley   +1 more source