Results 171 to 180 of about 196,000 (337)

Sustainable Sulfonic Acid Functionalized Tubular Shape Mesoporous Silica as a Heterogeneous Catalyst for Selective Unsymmetrical Friedel–Crafts Alkylation in One Pot

, 2023
Sanjay Singh, Amit Kumar, Leena Nebhani, Chinmoy Kumar Hazra   +3 more
openalex   +1 more source

Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview

Chemistry – A European Journal, EarlyView.
The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati, Claudio Trapella, Vinicio Zanirato, Virginia Cristofori, Anna Fantinati   +4 more
wiley   +1 more source

From alkylating to shape-shifting G-quadruplex ligands: the RHAU peptide story. [PDF]

Nucleic Acids Res
De Paepe L, Marzano S, Vesschemoet C, Amato J, Pagano B, Cadoni E, Madder A.   +6 more
europepmc   +1 more source

Studies in the derivatization of 4-(p-hydroxyphenyl)butan-2-one: O-alkylations, acetalizations, triloacetylations and synthesis of the respective regioselective 1,2-azoles by conventional and microwave methodology

, 2022
Taís B. Goulart
openalex   +1 more source

A Michaelis‐Arbuzov‐Type Pathway to a Protected 2ʹ‐Deoxy‐2ʹ‐Selenomethyl‐Adenosine‐3ʹ,5ʹ‐Phosphoroselenolate Guanosine Dinucleotide for Use in Modified m7G Cap Synthesis

Chemistry – A European Journal, EarlyView.
Here we report a synthesis of the dinucleotide 4 for a projected future total synthesis of the m7G cap 1. Highlights of the route include: 1) a 3ʹ‐H‐phosphonate/5ʹ‐selenocyanate Michaelis‐Arbuzov coupling to forge the 3ʹ,5ʹ‐phosphoroselenolate; 2) an Amosova reductive selenomethylation to install the 2ʹ‐SeMe; 3) a solid CPR II 5ʹ‐O‐phosphitylation; and
K. Lawrence E. Hale, Helen O. McCarthy, Mark G. McLaughlin   +2 more
wiley   +1 more source

General Light-Induced Pd-Catalyzed Allylic C-H Alkylation of Internal Alkenes: Direct Access to Tertiary and Quaternary Carbon Centers. [PDF]

J Am Chem Soc
Pradhan S, Prakash G, Gevorgyan V.
europepmc   +1 more source

Ruthenium-catalyzed ortho-C–H bond alkylation of aromatic amides with α,β-unsaturated ketones via bidentate-chelation assistance

, 2013
Guy Rouquet, Naoto Chatani
openalex   +2 more sources

Methyl on the Bridge: 2‐Methyl Propellane as Precursor for 1,3‐Substituted 2‐Methylated Bicyclo[1.1.1]Pentanes

Chemistry – A European Journal, EarlyView.
The synthesis of 2‐methyl propellane and its conversion to various 1,2‐ and 1,2,3‐di‐ and trisubstituted bicyclopentanes is reported. Abstract Bicyclo[1.1.1]pentanes (BCPs) have emerged as isosteric replacements for mono‐ and para‐substituted benzene rings in medicinal and materials applications, involving substitution at the BCP bridgehead (1,3 ...
Sean R. Verschaeve, Mariana Gomes Manso, Tibo Van Eeckhoorn, Mark E. Light, Bruno Linclau   +4 more
wiley   +1 more source

Late-stage adenine N6-alkylation of nucleos(t)ides and oligonucleotides via photoredox and copper co-catalytic decarboxylative C(sp3)-N coupling. [PDF]

Nat Commun
Xie R, Xiao G, Li W, Luochen W, Butt M, Que Y, Li X, Li Y, Sun L, Chen G.   +9 more
europepmc   +1 more source

A Simple Approach to Assign Disulfide Connectivity for Ziconotide Via Partial Reduction Without Alkylation

Peize Wu, Yuya Cheng, Weihua Wang, Ming Li   +3 more
openalex   +1 more source