Results 181 to 190 of about 89,156 (285)

5‐thiohistidine N‐acetyltransferase from Proteiniphilum saccharofermentans

open access: yesChemBioChem, Accepted Article.
Ovothiol A is a 5‐thiohistidine derivative biosynthesized by a broad range of prokaryotic and eukaryotic organisms. Its redox‐active mercaptoimidazole side chain is believed to protect cells from oxidative stress. The three enzymes that produce ovothiol A from histidine, cysteine, and S‐adenosyl methionine have been identified and characterized.
Cangsong Liao   +3 more
wiley   +1 more source

Activity‐Enhancing Mutations in an LmrR‐Based Artificial Metalloenzyme Destabilize the Protein Scaffold and Alter its Conformational Plasticity

open access: yesChemBioChem, EarlyView.
The protein LmrR is a versatile scaffold to design artificial metalloenzymes. Here, we show that the M8D/A92E (DE) mutations that result in a much more efficient catalyst, destabilize the protein dimerization interface and alter the conformation landscape when binding metal cofactor and substrates are shown.
Adil A. Safeer   +5 more
wiley   +1 more source

Bioactivity profiles of progressively ring‐fluorinated cyclohexyl motifs in the WKYMVm peptide as formylpeptide FPR2 agonists and in keto‐piperazines as anti‐trypanosome agents.

open access: yesChemBioChem, Accepted Article.
A series of all‐cis ring fluorinated cyclohexylalanines with progressively increasing levels of vicinal fluorines, as well as 4‐fluorophenylalanine and pentafluoroarylphenylalanine were introduced into the WKYMVm peptide in place of its tyrosine residue, for assays against the G‐protein coupled formylpeptide receptor, FPR2.
David O'Hagan   +6 more
wiley   +1 more source

Bioactive Polyketides from <i>Amphidinium</i> spp.: An In-Depth Review of Biosynthesis, Applications, and Current Research Trends. [PDF]

open access: yesMar Drugs
Russo N   +10 more
europepmc   +1 more source

Oxidative Dehydrogenation of Ethylbenzene over Iron‐Based Catalysts: Challenges, Prospects, and Future Trends

open access: yesChemCatChem, EarlyView.
This review discusses different aspects of the oxidative dehydrogenation reaction of ethylbenzene to styrene over iron‐based oxides, emphasizing the properties of the catalysts and the participation of active sites, as well as the deactivation and regeneration processes using soft oxidants.
Johnatan de Oliveira Soares   +2 more
wiley   +1 more source

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