Enhancing CHO cell recombinant protein production using a perfusion‐directed host evolution approach
Abstract Clonally derived cell lines generated from Chinese hamster ovary (CHO) cells encounter numerous stressors when cultured in high‐intensity perfusion bioreactors leading to poor process performance. To circumvent this, the ability of CHO cells to adapt to different culture environments was exploited. Here host cells were selected in the presence
Peter Amaya +7 more
wiley +1 more source
Molecular Origins of Simultaneous Chemo-, Enantio-, and Substrate Selectivity in Non-Natural Photoenzymatic Radical Reactions. [PDF]
Curtolo F, Dong SS.
europepmc +1 more source
ABSTRACT In the pursuit of novel antioxidant and anti‐inflammatory agents, we investigated 5‐hydroxyferulic acid (5‐OHFA), a hydroxylated derivative of the well‐known phenolic compound ferulic acid (FA). This study aimed to determine whether structural modification enhances the biological activity of FA.
Syrine Sakouhi +5 more
wiley +1 more source
Cobalt-Catalyzed Green Alkylations of Anilines with Tetrahydrofurans. [PDF]
Balalaeva AI +6 more
europepmc +1 more source
Synthesis and Octane Number of tert-Butyl Cyclohexane and 1,4-Di-tert-butyl Cyclohexane. Alkylation of Benzene with Isobutylene into tert-Butyl Benzene and p-Di-tert-butyl Benzene and their Hydrogenation [PDF]
Masaharu Katuno, Teturo Suwa
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Synthesis of 8‐hydroxyquinoline derivatives (QD 1‐12) from different analogues of 8‐hydroxyquinoline (HQ 1‐4). The derivatives and parent compounds were evaluated for antibacterial and antibiofilm activity against Mycobacterium tuberculosis, Mycobacterium smegmatis, methicillin‐resistant Staphylococcus aureus and methicillin‐sensitive Staphylococcus ...
Namrita Lall +9 more
wiley +1 more source
Chiral heterogeneous photocatalysts for enantioselective synthesis: standing on the shoulders of organocatalysis. [PDF]
Callegari C +3 more
europepmc +1 more source
Alkylation of Low Eutectic Energy-Containing Carrier Molecules: Design and Synthesis
Chaoqi Song +9 more
openalex +1 more source
Aminolyse, alkylation et rearrangement des β-cetoesters
Habi, Abdelkrim
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