Results 231 to 240 of about 116,077 (356)

Membrane‐Penetrating Molecular Device Based on a Triplex Containing Acyclic L‐Threoninol Nucleic Acid Functionalized with Cholesterol

open access: yesAngewandte Chemie, EarlyView.
A membrane‐penetrating molecular device composed of triplex containing cholesterol‐modified acyclic L‐threoninol nucleic acid (L‐aTNA) was achieved. This device is applied to a photo‐triggered signal transduction system functioning on giant unilamellar vesicles. Abstract Membrane‐penetrating molecular devices are valuable biological tools.
Kaifu Liu   +2 more
wiley   +1 more source

Alkyne-tagged ribitol-5-phosphate derivatives for metabolic labelling of alpha-dystroglycan. [PDF]

open access: yesRSC Chem Biol
Murphy LD   +9 more
europepmc   +1 more source

An Expanded Toolbox for Versatile Chemical Editing of Adeno‐Associated Virus

open access: yesAngewandte Chemie, EarlyView.
We describe technology to introduce diverse non‐natural chemical functionalities site‐specifically into the capsid of adeno‐associated virus through genetic code expansion, and using them to engineer this leading vector for human gene therapy for enhanced tissue specificity and reduced immunogenicity Abstract Site‐specific incorporation of noncanonical
Quan Pham   +6 more
wiley   +1 more source

Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics. [PDF]

open access: yesMol Cell Proteomics
Hou C   +10 more
europepmc   +1 more source

Efficient Preparation of Homogenous Antibody Conjugates via Glycosite‐Specific Transglycosylation Enabled by Readily Available Glycosyl Donors

open access: yesAngewandte Chemie, EarlyView.
A streamlined platform for glycosite‐specific antibody conjugation is enabled by LacNAc‐derived cyclic acetal donors, which can be prepared in only two steps and used directly in single‐enzyme Endo S2‐mediated transglycosylation. The platform supports the broad construction of homogeneous gsADCs and gsDACs, with donor 7 producing glycoengineered ...
Deqin Cai   +13 more
wiley   +1 more source

Toward Industrial Electrosynthesis of Ethylene: Energy‐Efficient and Stable Acetylene Semi‐Hydrogenation on a Copper Phosphide/MXene Electrocatalyst

open access: yesAngewandte Chemie, EarlyView.
Cu3P nanoparticles anchored on MXene via Ti─O─P bonds exhibit enhanced stability and resist agglomeration during the electrochemical semi‐hydrogenation of C2H2 to C2H4. Ti3C2/Cu3P achieves a record energy efficiency of 23.0% at 0.2 A cm−2 and stable operation in a 4 cm2 MEA for over 100 h at 1.0 A.
Zeliang Wu   +9 more
wiley   +1 more source

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