Results 241 to 250 of about 116,077 (356)

Chemical Proteomics Identifies Ketogenesis‐Mediated Cysteine Modifications Regulating Redox Function

Angewandte Chemie, EarlyView.
Herein, we report ketone body induce cysteine modifications beyond lysine acylation, as revealed by integrating chemical proteomics with open‐search methods. Among the modifications, cysteine crotonation (Ccr) was chemically validated by endogenous peptide‐based co‐elution assays.
Yuan‐Fei Zhou, Ling Zhang, Zhuoyi L. Niu, Xin Wang, Alejandro Storper, Ryan Hunt, Yingming Zhao, Nima Sharifi, Zhipeng A. Wang   +8 more
wiley   +1 more source

Visible-Light-Induced Bond Homolysis in Titanacyclopentadienes for the Catalytic Cyclodimerization of Internal Alkynes. [PDF]

J Am Chem Soc
Heldner ML, Körner T, Czernetzki C, Geppert PT, Nowak-Król A, Hierlmeier G.   +5 more
europepmc   +1 more source

Unnatural Amino Acid and Emerging Chemistry Approaches to Map RNA–Protein Interactions

Angewandte Chemie, EarlyView.
This review highlights emerging chemistries for mapping RNA–protein interactions, including genetically encoded unnatural amino acids, novel photocrosslinkers, and non‐photoactivatable crosslinking systems. We compare their mechanisms, reactivity and applications, outlining how these next‐generation tools enable higher‐resolution, site‐specific ...
Eryn Lundrigan, Parrish Evers, Elexa Scott, John Paul Pezacki   +3 more
wiley   +1 more source

Exploring the versatility of heterocyclic compounds containing nitrogen atoms (triazoles): a comprehensive review. [PDF]

RSC Adv
Akram M, Tamminana R.
europepmc   +1 more source

(Poly)Borylated Species as Modern Reactive Groups toward Unusual Synthetic Applications

Angewandte Chemie, EarlyView.
In this review, we spotlight recent breakthroughs in α‐polyboron‐substituted carbon‐centered intermediates (carbanion, carbocation, radical, and carbene) and polyborylated alkenes. By bridging fundamental reactivity with the application potential of these extraordinary species, we hope this review will serve as a roadmap for harnessing these unique ...
Nadim Eghbarieh, Nicole Hanania, Pinaki Nad, Tipu Alam, Tamir Kish, Ahmad Masarwa   +5 more
wiley   +1 more source

Correction: Critical assessment of copper-alginate hydrogel beads as recyclable and heterogeneous catalysts for aqueous azide‒alkyne cycloaddition. [PDF]

Front Chem
Moglie Y, Buxaderas E, González Cabrera A, Díaz DD.   +3 more
europepmc   +1 more source

Asymmetric Hydride Shift Reactions Catalyzed by Chiral Aluminium Complexes

Angewandte Chemie, EarlyView.
An asymmetric intramolecular hydride shift reaction has been developed that is catalyzed by Al Lewis acids in conjunction with a chiral BINOL‐derived ligand. Racemic THP substrates are transformed into cyclohexene products via an intermediate prochiral enone; which undergoes a key 1,5‐hydride shift reaction.
Mostafa M. Amer, Jingyan Hou, Jinfang Wang, Akvile Mazeikaite, Timothy J. Donohoe   +4 more
wiley   +1 more source

Late-stage peptide modification with salicylaldehyde tag enhances affinity for nuclear factor-kappa B essential modulator. [PDF]

RSC Chem Biol
Mason M, Peqini K, Uggeri F, Rondelli D, Sattin S, Pignataro L, Pellegrino S, Belvisi L, Scarpa E, Bucci R, Dal Corso A.   +10 more
europepmc   +1 more source

Novel Sulfonium Reagents for the Modular Synthesis of Spiro[2.3]Hexanes and Heteroatom‐Containing Analogues: Synthesis, Application, and Evaluation as Bioisosteres

Angewandte Chemie, EarlyView.
Strained spirocyclic spiro[2.3]hexane and its heteroatom‐containing derivatives, including previously underrepresented 5‐oxa‐1‐azaspiro[2.3]hexanes and 1,5‐diazaspiro[2.3]hexanes, were synthesized via a modular approach of insertion of cyclobutane‐, oxetane‐, and azetidine‐containing sulfonium reagents into alkenes, carbonyls and imines.
Philipp Natho, Annarita Vicenti, Fabrizio Mastrolorito, Francesca De Franco, Lee Walsh‐Benn, Marco Colella, Ernesto Mesto, Emanuela Schingaro, Orazio Nicolotti, Antimo Gioiello, Renzo Luisi   +10 more
wiley   +1 more source

Thianthrenium Chemistry for Identification of Protein-Protein Interactions in Cells. [PDF]

J Am Chem Soc
Bohdan K, Hartmann P, Müller S, Marchionni D, Preisinger C, Jacobs JB, Vogelsang L, Sterling MS, Dietz KJ, Ritter T.   +9 more
europepmc   +1 more source