Results 131 to 140 of about 82,660 (245)
PAF Triggered Pyroptotic NETosis Aggravates Myocardial Ischemia/Reperfusion Injury
Advanced Science, Volume 13, Issue 25, 4 May 2026.Platelet activating factor (PAF) secreted by cardiomyocytes during MI/R, drives NETs formation and subsequent NETosis. PAF/NETosis signaling activation is an initiative and causal factor in driving MI/R injury. This study identifies dapagliflozin as a potent NETosis inhibitor, and demonstrates that manipulating PAF‐NETosis signal by dapagliflozin or ...
Jiawei Wu +11 more
wiley +1 more source
Effect of "All - trans" retinoic acid in canine osteosarcoma chemotherapy. [PDF]
, 2008 Ciarcia, R. +6 more
core +1 more source
Retinoic acid induces the differentiation of B cell hybridomas from patients with common variable immunodeficiency. [PDF]
, 1988 Human-human B cell hybridomas constructed from B lymphocytes of common variable immunodeficiency (CVI) patients and the nonsecreting cell line WIL2/729 HF consistently secrete low levels of Ig and appear to retain a defect characteristic of the CVI ...
Adelman, DC +5 more
core
Molecular Carcinogenesis, Volume 65, Issue 5, Page 556-564, May 2026.ABSTRACT Early diagnosis of acute promyelocytic leukemia (APL), driven by PML‐RARA oncoprotein, is vital for survival, as delays can cause fatal coagulopathy without prompt therapeutic intervention of all‐trans retinoic acid and arsenic trioxide. Although APL is diagnosed using microscopy, immunophenotyping, and FISH/PCR for PML‐RARA, morphological ...
Akash Maity +17 more
wiley +1 more source
Isocitrate Dehydrogenase Mutations in Cancer: From Bench to Bedside Applications
MedComm, Volume 7, Issue 5, May 2026.Mutant isocitrate dehydrogenase affects multiple cancer types. Alterations in IDH1 and IDH2 result in abnormal enzyme activity, leading to the overproduction of D‐2‐hydroxyglutarate (D‐2HG). This metabolite disrupts cellular metabolism and epigenetic regulation, driving cancer initiation, progression, and metastasis.
Yuhan Fang +6 more
wiley +1 more source
Propionibacterium acnes Induces an IL-17 Response in Acne Vulgaris that Is Regulated by Vitamin A and Vitamin D. [PDF]
, 2014 Acne vulgaris is the most common skin disorder affecting millions of people worldwide and inflammation resulting from the immune response targeting Propionibacterium acnes has a significant role in its pathogenesis.
Agak, George W +8 more
core
The FASEB Journal, Volume 40, Issue 8, 30 April 2026.The purification protocol for hypertrophied hepatic stellate cells (hypHSCs) developed in this study, using fibrotic and steatotic mouse livers (CDAHFD model), made it possible to obtain a high‐purity hypHSC preparation for transcriptomic analysis.
Marion Heckmann +9 more
wiley +1 more source
CITP SOP: all-trans retinoic acid
Standard operating procedure for all-trans retinoic acid stock solution and plate treatment from the Caenorhabditis Intervention Testing Program (CITP) manuscript: Survey of anti-aging computational predictions identifies all-trans retinoic acid modulation of conserved longevity pathways in genetically diverse Caenorhabditis ...
openaire +1 more source
Nanoparticle delivery and combination therapy of gambogic acid and all-trans retinoic acid
International Journal of Nanomedicine, 2014 Jing Yao, Yuanke Li, Xiaojing Sun, Fatima Zohra Dahmani, Hongpan Liu, Jianping Zhou State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, People’s Republic of China Abstract: In order to enhance the in vivo ...
Yao J +5 more
doaj
Treatment of adult patients with acute promyelocytic leukemia according to the AIDA protocol
Терапевтический архив, 2013 AIM: To give the results of an investigation conducted at the Hematology Research Center (HRC), Ministry of Health of the Russian Federation (MHRF), to treat adult patients with acute promyelocytic leukemia (APL) according to the AIDA protocol elaborated
E N Parovichnikova +8 more
doaj