Results 201 to 210 of about 18,841,230 (238)
Some of the next articles are maybe not open access.
Topical application of all-trans-retinoic acid
Graefe's Archive for Clinical and Experimental Ophthalmology, 1988A 0.1% all-trans-retinoic acid in petroleum-base ointment was applied daily in eight normal rabbit eyes. Epithelial samples were collected from the cornea and limbus of six rabbits by impression cytology at 3- to 4-day intervals. Cytological changes were followed for 21 days and the eyes subsequently harvested for histochemical, scanning electron ...
K G, Stonecipher +3 more
openaire +2 more sources
Retinoic Acid, All-trans Retinoic Acid (ATRA), and Tamibarotene
2017Retinoids, all-trans retinoic acid (ATRA), and tamibarotene can induce differentiation of leukemic cells that carry t(15;17) and potentially lead to complete remission (CR) in patients with acute promyelocytic leukemia (APL). Although introduction of ATRA as a differentiating agent has been a major breakthrough in the treatment of APL, ATRA is ...
openaire +1 more source
Nuclear all-trans retinoic acid receptors
Biological Trace Element Research, 1998The present study was undertaken to investigate the effects of selenite (SeIV) and selenate (SeVI) on the all-trans retinoic acid (RA)-nuclear retinoic acid receptor (RAR) complex formation in rat liver. We also present the data on the in vitro effects of SeIV on the RARalpha and the type I iodothyronine 5'-deiodinase gene expression in the GH4C1 rat ...
J, Brtko +4 more
openaire +2 more sources
Tretinoin (all-trans-Retinoic Acid, Vitamin A Acid)
1993Vitamin A and its derivatives have been known for over 40 years to influence keratinization and epithelial differentiation. In 1962, Stuttgen in Dusseldorf and Beer in Basel independently demonstrated the efficacy of topical tretinoin (retinoic acid, vitamin A acid) in various neoplasms of the skin and chronic hyperkeratotic disorders, especially ...
Gerd Plewig, Albert M. Kligman
openaire +1 more source
The Journal of the Association of Physicians of India, 1996
ATRA is extremely effective for inducing clinical remission in APML. The presence of PML/RAR-alpha fusion gene produced as a result of the unique chromosomal translocation in APML is a marker of the sensitivity to ATRA therapy. Further research is needed to elucidate the mechanisms by which the development of the fusion protein in APML leads to the ...
openaire +1 more source
ATRA is extremely effective for inducing clinical remission in APML. The presence of PML/RAR-alpha fusion gene produced as a result of the unique chromosomal translocation in APML is a marker of the sensitivity to ATRA therapy. Further research is needed to elucidate the mechanisms by which the development of the fusion protein in APML leads to the ...
openaire +1 more source
The Journal of Nutritional Biochemistry, 1991
Abstract Increments of levels of both 13-cis- and all-trans-retinoic acid in human plasma were observed after either a physiologic or a pharmacologic oral dose of all-trans-retinyl palmitate. Subjects receiving a physiologic dose showed mean ± SEM plasma rises over baseline as follows: all-trans-retinoic acid = 1.1 ± 0.3 nmol/L and 13-cis-retinoic ...
openaire +1 more source
Abstract Increments of levels of both 13-cis- and all-trans-retinoic acid in human plasma were observed after either a physiologic or a pharmacologic oral dose of all-trans-retinyl palmitate. Subjects receiving a physiologic dose showed mean ± SEM plasma rises over baseline as follows: all-trans-retinoic acid = 1.1 ± 0.3 nmol/L and 13-cis-retinoic ...
openaire +1 more source
[All-trans retinoic acid (Tretinoin)].
Gan to kagaku ryoho. Cancer & chemotherapy, 1997Differentiation therapy with all-trans retinoic acid (ATRA, tretinoin) alone or in combination with chemotherapy induces around 90% complete remission in acute promyelocytic leukemia (APL). By giving non-cross resistant chemotherapy as postremission therapy, more than 50% of APL, especially more than 70% of APL patients of age less than 30, became ...
openaire +1 more source
Retinoids (13-Cis-Retinoic Acid, Isotretinoin, Accutane, All-Trans-Retinoic Acid)
2015Isotretinoin is a synthetic form of vitamin A that has been used in the United States since 1983 mainly for the treatment of severe cystic acne. Long-term therapy with low-dose isotretinoin has also been used for prevention of basal cell carcinoma and treatment of cutaneous T-cell lymphomas, and all-trans-retinoic acid (ATRA) has been used in patients ...
openaire +1 more source
Retinoic acid syndrome associated with all trans retinoic acid
2019[No abstract available]
openaire +1 more source
All-trans retinoic acid in myelogenous leukaemia
The Lancet, 1991R E, Gallagher, P H, Wiernik
openaire +2 more sources