Use of allele scores as instrumental variables for Mendelian randomization
International Journal of Epidemiology, 2013 Background An allele score is a single variable summarizing multiple genetic variants associated with a risk factor. It is calculated as the total number of risk factor-increasing alleles for an individual (unweighted score), or the sum of weights for ...
S. Burgess, S. Thompson
semanticscholar +1 more source
IoTThe rapid expansion of the Internet of Things (IoT) has steered in a new generation of connectivity and data-driven decision-making across diverse industrial sectors. As IoT deployments continue to expand, the need for robust and reliable data management
Driss Riane +2 more
doaj +1 more source
Revista Brasileira de Reumatologia, 2010 INTRODUÇÃO: A artrite reumatoide (AR) é uma doença inflamatória crônica sistêmica autoimune que provém de uma desordem incapacitante. Até hoje, a etiologia da AR é desconhecida. No entanto, já se cogitou a existência de indivíduos geneticamente passíveis
María Verónica Aguirre Arias +5 more
doaj +1 more source
RNA Levels and Activity of \u3cem\u3eFLOWERING LOCUS C\u3c/em\u3e are Modified in Mixed Genetic Backgrounds of \u3cem\u3eArabidopsis Thaliana\u3c/em\u3e [PDF]
, 2001 Flowering time and FLOWERING LOCUS C (FLC) RNA levels were analyzed in different accessions of Arabidopsis thaliana and in mixed genetic backgrounds resulting from crosses between accessions.
Schläppi, Michael
core +1 more source
Allele-sharing models: LOD scores and accurate linkage tests.
American Journal of Human Genetics, 1997 Starting with a test statistic for linkage analysis based on allele sharing, we propose an associated one-parameter model. Under general missing-data patterns, this model allows exact calculation of likelihood ratios and LOD scores and has been ...
A. Kong, A. Kong, N. Cox
semanticscholar +1 more source
On Wild-Type Iso-Alleles in Drosophila Melanogaster [PDF]
, 1943 Curt Stern, Elizabeth White Schaeffer
openalex +1 more source
An Engineered Nonsense \u3cem\u3eURA3\u3c/em\u3e Allele Provides a Versatile System to Detect the Presence, Absence and Appearance of the [em\u3ePSI\u3c/em\u3e\u3csup\u3e+\u3c/sup\u3e] Prion in \u3cem\u3eSaccharomyces cerevisiae\u3c/em\u3e [PDF]
, 2006 Common methods to identify yeast cells containing the prion form of the Sup35 translation termination factor, [PSI+], involve a nonsense suppressor phenotype. Decreased function of Sup35p in [PSI+] cells leads to readthrough of certain nonsense mutations
Kirkland, Kathryn T. +2 more
core +1 more source
VARIATION IN THE HOODED PATTERN OF RATS, AND A NEW ALLELE OF HOODED [PDF]
, 1951 W. E. Castle
openalex +1 more source
High-Complexity Plasmodium falciparum Infections, North Central Nigeria, 2015–2018
Emerging Infectious Diseases, 2019 The mass migration that occurred during 2009–2013 and after the insurgency in northeastern Nigeria could have increased malaria incidence and Plasmodium falciparum genetic diversity in North Central Nigeria. To determine P.
Bitrus Yakubu +4 more
doaj +1 more source
The Effect of Olanzapine on Craving and Alcohol Consumption
, 2006 Previous studies have indicated that olanzapine decreases craving after a priming dose of alcohol, that craving after a priming dose of alcohol is greater among individuals with the seven-repeat allele of the DRD4 variable number of tandem repeats (VNTR)
Davidson, Dena +6 more
core