Results 41 to 50 of about 1,121,623 (279)

Polymorphism of Blood Serum Protein- Transferrin, Ceruloplasmin, Albumin- in Sheep of Karabakh Breed and the Relationship with the Natural Resistance Towards Epizootic Aphtae

Scientific Papers Animal Science and Biotechnologies, 2023
New genetic methods are currently used in selection activities of agricultural animals, based on polymorph genetic determination systems, which, serving as genetic markers, enable studying animal genealogy, alelofon, genotypes.
Manvel Badalyan, Gayane Marmaryan, Yuri Marmaryan   +2 more
doaj  

High-Throughput MICA/B Genotyping of Over Two Million Samples: Workflow and Allele Frequencies

Frontiers in Immunology, 2020
MICA and MICB are ligands of the NKG2D receptor and thereby influence NK and T cell activity. MICA/B gene polymorphisms, expression levels and the amount of soluble MICA/B in the serum have been linked to autoimmune diseases, infections, and cancer.
Anja Klussmeier, Carolin Massalski, Kathrin Putke, Gesine Schäfer, Jürgen Sauter, Daniel Schefzyk, Jens Pruschke, Jan Hofmann, Daniel Fürst, Daniel Fürst, Raphael Carapito, Seiamak Bahram, Alexander H. Schmidt, Alexander H. Schmidt, Vinzenz Lange   +14 more
doaj   +1 more source

Monitoring for the genetic structure of Mezen breed of horses in terms of DNA microsatellites

Вавиловский журнал генетики и селекции, 2021
Mezenskaya horse (Mezenka) is Russia’s aboriginal breed. It is a domestic selection in the northern territories of Arkhangelsk region. The breed is perfectly adapted to the conditions of the Far North, and has a number of valuable economic and biological
N. V. Vdovina, I. B. Yuryeva
doaj   +1 more source

Exome sequencing identifies nonsegregating nonsense ATM and PALB2 variants in familial pancreatic cancer. [PDF]

, 2013
We sequenced 11 germline exomes from five families with familial pancreatic cancer (FPC). One proband had a germline nonsense variant in ATM with somatic loss of the variant allele. Another proband had a nonsense variant in PALB2 with somatic loss of the
Al-Sukhni, Wigdan, Borgida, Ayelet E, Gallinger, Steven, Grant, Robert C, Holter, Spring, Kanji, Zaheer S, McPherson, John D, McPherson, Treasa, Peltekova, Vanya, Serra, Stefano, Stein, Lincoln D, Trinh, Quang M, Whelan, Emily   +12 more
core   +3 more sources

Impact of the CACNA1G rs757415 polymorphism on grey matter volume in patients with bipolar disorder

Sichuan jingshen weisheng
BackgroundBipolar disorder is a severe mental disorder characterized by cycling between mania/hypomania and depression， yet its underlying pathophysiological mechanism remains unclear.
Cheng Xiaofei, Yang Qian, Nie Yirou, Zhang Mengmeng, Xie Yi, Li Mingli   +5 more
doaj   +1 more source

Novel Schizophrenia Risk Gene TCF4 Influences Verbal Learning and Memory Functioning in Schizophrenia Patients [PDF]

, 2011
Background: Recently, a role of the transcription factor 4 (TCF4) gene in schizophrenia has been reported in a large genome-wide association study. It has been hypothesized that TCF4 affects normal brain development and TCF4 has been related to different
Aleman A, Anna Schuhmacher, Bogerts B, Dan Rujescu, Hans-Jürgen Möller, Heinz Häfner, Ingo Frommann, Leonhard Lennertz, Martin W. Landsberg, Michael Wagner, Petra Franke, Pitt D, Rainald Mössner, Saykin AJ, Stefánsson H, Svenja Schulze-Rauschenbach, Whyte MC, Wolfgang Gaebel, Wolfgang Maier, Wolfgang Wölwer, Wright IC   +20 more
core   +1 more source

HLA-A and -B alleles and haplotypes in hemochromatosis probands with HFE C282Y homozygosity in central Alabama

BMC Medical Genetics, 2002
Background We wanted to quantify HLA-A and -B allele and haplotype frequencies in Alabama hemochromatosis probands with HFE C282Y homozygosity and controls, and to compare results to those in other populations.
Barton James C, Acton Ronald T
doaj   +1 more source

Allele-Specific Isothermal Amplification Method Using Unmodified Self-Stabilizing Competitive Primers. [PDF]

, 2018
Rapid and specific detection of single nucleotide polymorphisms (SNPs) related to drug resistance in infectious diseases is crucial for accurate prognostics, therapeutics and disease management at point-of-care.
Baum, Jake, Chotivanich, Kesinee, Delves, Michael J, Georgiou, Pantelis, Malpartida-Cardenas, Kenny, Nguon, Chea, Rodriguez-Manzano, Jesus, Yu, Ling-Shan   +7 more
core   +2 more sources

Cognitive Functioning in Vorinostat‐Treated Pediatric and Young Adult Patients Over the First 180 Days After Hematopoietic Stem Cell Transplant

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Cognitive and psychological difficulties could negatively interfere with treatment adherence and quality of life before and after hematopoietic stem cell transplant (HSCT). Methods to mitigate these changes may have positive effects on treatment success.
Kristen L. Votruba, Michelle Rozwadowski, Thomas Braun, April Rahrig, Edward Peres, Kirsten M. Williams, Vanessa Fabrizio, Julie‐An Talano, Carrie L. Kitko, Nicolas Parnell, Pavan Reddy, Sung Won Choi   +11 more
wiley   +1 more source

Artificial escape from XCI by DNA methylation editing of the CDKL5 gene. [PDF]

, 2020
A significant number of X-linked genes escape from X chromosome inactivation and are associated with a distinct epigenetic signature. One epigenetic modification that strongly correlates with X-escape is reduced DNA methylation in promoter regions. Here,
Anderson, Johnathon D, Buchanan, Fiona KB, Cameron, David, Carter, Jasmine L, Coggins, Nicole B, Deng, Peter, Fink, Kyle D, Gonzalez, Casiana E, Halmai, Julian ANM, Halmai, Julian ANM, Lock, Samantha R, Nolta, Jan, O'Geen, Henriette, Segal, David J, Waldo, Jennifer J   +14 more
core   +1 more source