Results 41 to 50 of about 1,163,092 (332)
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
IoTThe rapid expansion of the Internet of Things (IoT) has steered in a new generation of connectivity and data-driven decision-making across diverse industrial sectors. As IoT deployments continue to expand, the need for robust and reliable data management
Driss Riane +2 more
doaj +1 more source
TECHNOLOGICAL PROPERTIES OF MILK OF COWS WITH DIFFERENT GENOTYPES OF KAPPA-CASEIN AND BETA-LACTOGLOBULIN [PDF]
Foods and Raw Materials, 2018 The presence of the desirable alleles and genotypes of casein and whey protein genes in the genome of cows affects the milk protein content, quality and technological properties of their milk.
Tyulkin S.V. +5 more
doaj +1 more source
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
Scientific Papers Animal Science and Biotechnologies, 2023 New genetic methods are currently used in selection activities of agricultural animals, based on polymorph genetic determination systems, which, serving as genetic markers, enable studying animal genealogy, alelofon, genotypes.
Manvel Badalyan +2 more
doaj
Polymorphism of KIR2DL4 gene among northern Chinese Han population
Zhongguo shuxue zazhi, 2022 Objective To investigate the polymorphism of KIR2DL4 gene in northern Chinese Han population. Methods A total of 327 DNA samples were isolated by magnetic beads from unrelated individuals of northern Chinese Han population.
Zhichao YANG +4 more
doaj +1 more source
The cis-AB01 Allele Originated From the A105 Allele, and not From the A102 Allele
Annals of Laboratory Medicine, 2015 Researchers in the field of transfusion medicine have a growing interest in the cis-AB blood group, which is characterized by a paradoxical inheritance of the ABO blood group [1]. The cis-AB blood group arises from a glycosyltransferase capable of synthesizing both A and B antigens simultaneously [2]. In addition, affected individuals display more than
Myung-Geun Shin +4 more
openaire +3 more sources
Non-equilibrium theory of the allele frequency spectrum [PDF]
, 2006 A forward diffusion equation describing the evolution of the allele frequency spectrum is presented. The influx of mutations is accounted for by imposing a suitable boundary condition.
Evans, Steven N. +2 more
core +2 more sources
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
Frontiers in Oncology, 2019 Epigenetic information is characterized by its stable transmission during mitotic cell divisions and plasticity during development and differentiation. This duality is in contrast to genetic information, which is stable and identical in all cells in an ...
Maxwell P. Lee
doaj +1 more source