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Allergen immunotherapy: past, present and future
Nature Reviews Immunology, 2022 Durham and Shamji review the history and future of allergen immunotherapy for established IgE-mediated hypersensitivity to common allergens. They describe the mechanisms of immunotherapy-induced tolerance and the new strategies being explored to achieve ...
Stephen Durham
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The role of allergen‐specific IgE, IgG and IgA in allergic disease
Allergy: European Journal of Allergy and Clinical Immunology, 2021 Immunoglobulin E (IgE)‐mediated allergy is the most common hypersensitivity disease affecting more than 30% of the population. Exposure to even minute quantities of allergens can lead to the production of IgE antibodies in atopic individuals.
Mohamed Shamji +2 more
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Allergen-Specific Antibodies Regulate Secondary Allergen-Specific Immune Responses
Frontiers in Immunology, 2019 Immunoglobulin E (IgE)-associated allergy is the most common immunologically-mediated hypersensensitivity disease. It is based on the production of IgE antibodies and T cell responses against per se innocuous antigens (i.e., allergens) and subsequent ...
Julia Eckl-Dorna +9 more
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Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement
Nature Communications, 2018 Acute allergic symptoms are caused by allergen-induced crosslinking of allergen-specific immunoglobulin E (IgE) bound to Fc-epsilon receptors on effector cells.
Andrew J Murphy
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EAACI Guidelines on Allergen Immunotherapy: Allergic rhinoconjunctivitis
Allergy: European Journal of Allergy and Clinical Immunology, 2018 Graham C Roberts, Oliver Pfaar
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Allergen immunotherapy for IgE‐mediated food allergy: a systematic review and meta‐analysis
Allergy: European Journal of Allergy and Clinical Immunology, 2017 Sangeeta Dhami +2 more
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Allergen immunotherapy for allergic asthma: A systematic review and meta‐analysis
Allergy: European Journal of Allergy and Clinical Immunology, 2017 Sangeeta Dhami +2 more
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Vaccines, 2023 To achieve maximum efficacy, vaccines, such as subunit, recombinant, and conjugate vaccines, necessitate the incorporation of immunostimulators/adjuvants.
Junli Li +7 more
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Vaccines, 2022 Both adaptive and innate immunity responses are necessary for the efficient elimination of different pathogens. However, the magnitude, quality and desired type of immune response specific to the co-administered antigen is largely determined by adjuvants.
Junli Li +6 more
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Vaccines, 2022 Herpes zoster (HZ) is one of two distinct syndromes caused by Varicella-zoster virus (VZV). A primary infection with VZV causes varicella in susceptible young children.
Junli Li +4 more
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