Results 1 to 10 of about 250,033 (360)

Comparison of the Immune Responses to Different Formulations of BC02-Adjuvanted HPV Types 16 and 18 Bivalent Vaccines in Mice

Vaccines, 2023
To achieve maximum efficacy, vaccines, such as subunit, recombinant, and conjugate vaccines, necessitate the incorporation of immunostimulators/adjuvants.
Junli Li, Huicong Xie, Lili Fu, Xiaonan Guo, Jiaxin Dong, Miao Xu, Guozhi Wang, Aihua Zhao   +7 more
doaj   +1 more source

Novel BC02 Compound Adjuvant Enhances Adaptive and Innate Immunity Induced by Recombinant Glycoprotein E of Varicella-Zoster Virus

Vaccines, 2022
Both adaptive and innate immunity responses are necessary for the efficient elimination of different pathogens. However, the magnitude, quality and desired type of immune response specific to the co-administered antigen is largely determined by adjuvants.
Junli Li, Lili Fu, Xiaonan Guo, Yang Yang, Jiaxin Dong, Guozhi Wang, Aihua Zhao   +6 more
doaj   +1 more source

Enhanced Potency and Persistence of Immunity to Varicella-Zoster Virus Glycoprotein E in Mice by Addition of a Novel BC02 Compound Adjuvant

Vaccines, 2022
Herpes zoster (HZ) is one of two distinct syndromes caused by Varicella-zoster virus (VZV). A primary infection with VZV causes varicella in susceptible young children.
Junli Li, Lili Fu, Yang Yang, Guozhi Wang, Aihua Zhao   +4 more
doaj   +1 more source

Past, Present and Future of Bacillus Calmette-Guérin Vaccine Use in China

Vaccines, 2022
The BCG vaccine is prepared from a weakened strain of Mycobacterium bovis (M. bovis), a bacterium closely related to Mycobacterium tuberculosis (MTB), which causes tuberculosis (TB).
Junli Li, Jinbiao Lu, Guozhi Wang, Aihua Zhao, Miao Xu   +4 more
doaj   +1 more source

Is peanut causing food allergy in Cuba? Preliminary assessment of allergic sensitization and IgE specificity profile to peanut allergens in Cuban allergic patients

World Allergy Organization Journal, 2017
Background Peanut allergy is increasing at an alarming pace in developed countries. Peanut (Arachis hypogaea) is a common food in Cuba. Nevertheless, reported values of sensitization and symptom severity are usually low.
Mayteé Mateo-Morejón, Alexis Labrada-Rosado, Damaris Torralba-Averoff, Rayza Cruz-Jimenez, Yunia Oliva-Díaz, Mirta Álvarez-Castelló, Alexander Ciria-Martín, Marlene Jiménez-Frandín, Mary Carmen Reyes-Zamora, Raúl Lázaro Castro-Almarales, Beatriz Tamargo-García   +10 more
doaj   +3 more sources

The Subunit AEC/BC02 Vaccine Combined with Antibiotics Provides Protection in Mycobacterium tuberculosis-Infected Guinea Pigs

Vaccines, 2022
A latent tuberculosis infection (LTBI) is a major source of active tuberculosis, and addressing an LTBI is crucial for the elimination of tuberculosis.
Xiaonan Guo, Jinbiao Lu, Junli Li, Weixin Du, Xiaobing Shen, Cheng Su, Yongge Wu, Aihua Zhao, Miao Xu   +8 more
doaj   +1 more source

Pollen allergen products: current standardisation issues

Биопрепараты: Профилактика, диагностика, лечение, 2023
Scientific relevance. Pollen allergen medicines are in high demand, and their therapeutic benefits directly correlate with their standardisation. Better diagnosis and treatment of allergic diseases require state-of-the-art procedures for assessing the ...
E. I. Sakanyan, M. A. Yasnaya, V. F. Vul, R. A. Bubenchikov, N. V. Vinokurova, E. S. Yurtaeva   +5 more
doaj   +1 more source

Therapeutic Effect of Subunit Vaccine AEC/BC02 on Mycobacterium tuberculosis Post-Chemotherapy Relapse Using a Latent Infection Murine Model

Vaccines, 2022
Tuberculosis (TB), caused by the human pathogen Mycobacterium tuberculosis (Mtb), is an infectious disease that presents a major threat to human health.
Jinbiao Lu, Xiaonan Guo, Chunhua Wang, Weixin Du, Xiaobing Shen, Cheng Su, Yongge Wu, Miao Xu   +7 more
doaj   +1 more source

Cytokine profile in childhood asthma

Journal of Medical Science, 2022
Childhood asthma is a chronic airway disease, which pathogenesis is markedly heterogeneous–with multiple phenotypes defining visible characteristics and endotypes defining molecular mechanisms.
Joanna Matysiak, Kacper Packi, Sylwia Klimczak, Patrycja Bukowska, Eliza Matuszewska, Agnieszka Klupczyńska-Gabryszak, Anna Bręborowicz, Jan Matysiak   +7 more
doaj   +1 more source

Airway responses and inflammation in subjects with asthma after four days of repeated high-single-dose allergen challenge [PDF]

, 2012
Background: Both standard and low-dose allergen provocations are an established tool in asthma research to improve our understanding of the pathophysiological mechanism of allergic asthma.
Rose, Markus A., Schubert, Ralf, Schulze, Johannes, Voss, Sandra, Zielen, Stefan, Zissler, Ulrich   +5 more
core   +2 more sources