Results 1 to 10 of about 135,884 (265)

Therapeutic Effect of Subunit Vaccine AEC/BC02 on Mycobacterium tuberculosis Post-Chemotherapy Relapse Using a Latent Infection Murine Model

open access: yesVaccines, 2022
Tuberculosis (TB), caused by the human pathogen Mycobacterium tuberculosis (Mtb), is an infectious disease that presents a major threat to human health.
Jinbiao Lu   +7 more
doaj   +1 more source

Cytokine profile in childhood asthma

open access: yesJournal of Medical Science, 2022
Childhood asthma is a chronic airway disease, which pathogenesis is markedly heterogeneous–with multiple phenotypes defining visible characteristics and endotypes defining molecular mechanisms.
Joanna Matysiak   +7 more
doaj   +1 more source

A Review of Honeybee Venom Allergens and Allergenicity [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
Honeybee venom is a source of proteins with allergenic properties which can result in in various symptoms, ranging from local reactions through to systematic life-threatening anaphylaxis, or even death. According to the World Allergy Organization (WAO), honeybee venom allergy is one of the most common causes of anaphylaxis.
Marta Burzyńska   +1 more
openaire   +2 more sources

The Fate of IgE Epitopes and Coeliac Toxic Motifs during Simulated Gastrointestinal Digestion of Pizza Base

open access: yesFoods, 2022
Understanding how food processing may modify allergen bioaccessibility and the evolution of immunologically active peptides in the gastrointestinal tract is essential if knowledge-based approaches to reducing the allergenicity of food are to be realised.
Matthew E. Daly   +8 more
doaj   +1 more source

Japanese Society of Allergology task force report on standardization of house dust mite allergen vaccines – Secondary publication

open access: yesAllergology International, 2015
Background: In the 1990s, the Japanese Society of Allergology (JSA) standardized Japanese cedar pollen allergen vaccines. In the present study, the task force for house dust mite (HDM) allergen standardization of the Committee for Allergens and ...
Toshiro Takai   +8 more
doaj   +1 more source

What Makes an Allergen an Allergen [PDF]

open access: yesAllergy, 1978
In the vocabulary of daily life the term allergen is most often used to indicate the whole substance able to initiate an allergic reaction, such as certain pollens, moulds, house dust mites, animal dander, cow's milk and other inhalants or food items known to trigger immediate or late, hypersensitivity reactions.
openaire   +2 more sources

Climate change, aeroallergens, and the aeroexposome

open access: yesEnvironmental Research Letters, 2021
Allergic diseases are a major public health problem globally and are increasing. The impacts of climate change on aeroallergens such as pollen and fungal spores and allergic respiratory diseases such as allergic asthma and allergic rhinitis have been ...
Paul J Beggs
doaj   +1 more source

Multigenerational Epigenetic Regulation of Allergic Diseases: Utilizing an Experimental Dust Mite-Induced Asthma Model

open access: yesFrontiers in Genetics, 2021
Environmental exposures have been linked to increased asthma risk, particularly during pregnancy and in early life. Here we use a mouse model of allergic lung disease to examine the effects of pre- and perinatal house dust mite (HDM) allergen exposure on
Jairus C. Pulczinski   +8 more
doaj   +1 more source

Regulation and directed inhibition of ECP production by human neutrophils

open access: yesFrontiers in Immunology, 2022
BackgroundNeutrophils are involved in the pathophysiology of allergic asthma, where the Eosinophil Cationic Protein (ECP) is a critical inflammatory mediator.
Antonio Vega-Rioja   +18 more
doaj   +1 more source

Allergen Peptides, Recombinant Allergens and Hypoallergens for Allergen-Specific Immunotherapy [PDF]

open access: yesCurrent Treatment Options in Allergy, 2014
Allergic diseases are among the most common health issues worldwide. Specific immunotherapy has remained the only disease-modifying treatment, but it is not effective in all patients and may cause side effects. Over the last 25 years, allergen molecules from most prevalent allergen sources have been isolated and produced as recombinant proteins.
Marth, Katharina   +4 more
openaire   +2 more sources

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