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What Makes an Allergen an Allergen [PDF]
In the vocabulary of daily life the term allergen is most often used to indicate the whole substance able to initiate an allergic reaction, such as certain pollens, moulds, house dust mites, animal dander, cow's milk and other inhalants or food items known to trigger immediate or late, hypersensitivity reactions.
Kjell Aas
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SummaryThis article presents a nomenclature system for allergens which has been officially recommended by the International Union of Immunological Societies (IUIS). The nomenclature is based on proposals of the IUIS Sub‐Committee for Allergen Nomenclature and is applicable to highly purified, well‐characterized allergens and to non‐purified or ...
David G. Marsh+4 more
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Allergen-Specific Antibodies Regulate Secondary Allergen-Specific Immune Responses
Immunoglobulin E (IgE)-associated allergy is the most common immunologically-mediated hypersensensitivity disease. It is based on the production of IgE antibodies and T cell responses against per se innocuous antigens (i.e., allergens) and subsequent ...
Julia Eckl-Dorna+9 more
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A systematic review and economic evaluation of subcutaneous and sublingual allergen immunotherapy in adults and children with seasonal allergic rhinitis [PDF]
Background: Severe allergic rhinitis uncontrolled by conventional medication can substantially affect quality of life. Immunotherapy involves administering increasing doses of a specific allergen, with the aim of reducing sensitivity and symptomatic ...
A Meadows+7 more
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To achieve maximum efficacy, vaccines, such as subunit, recombinant, and conjugate vaccines, necessitate the incorporation of immunostimulators/adjuvants.
Junli Li+7 more
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Both adaptive and innate immunity responses are necessary for the efficient elimination of different pathogens. However, the magnitude, quality and desired type of immune response specific to the co-administered antigen is largely determined by adjuvants.
Junli Li+6 more
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Impact of oligomerization on the allergenicity of allergens
AbstractType I hypersensitivity (allergic reaction) is an unsuitable or overreactive immune response to an allergen due to cross-link immunoglobulin E (IgE) antibodies bound to its high-affinity IgE receptors (FcεRIs) on effector cells. It is needless to say that at least two epitopes on allergens are required to the successful and effective cross ...
Amin Moradi Hasan-Abad+5 more
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The role of allergen‐specific IgE, IgG and IgA in allergic disease
Immunoglobulin E (IgE)‐mediated allergy is the most common hypersensitivity disease affecting more than 30% of the population. Exposure to even minute quantities of allergens can lead to the production of IgE antibodies in atopic individuals.
M. Shamji+6 more
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Herpes zoster (HZ) is one of two distinct syndromes caused by Varicella-zoster virus (VZV). A primary infection with VZV causes varicella in susceptible young children.
Junli Li+4 more
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Past, Present and Future of Bacillus Calmette-Guérin Vaccine Use in China
The BCG vaccine is prepared from a weakened strain of Mycobacterium bovis (M. bovis), a bacterium closely related to Mycobacterium tuberculosis (MTB), which causes tuberculosis (TB).
Junli Li+4 more
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