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What Makes an Allergen an Allergen [PDF]

open access: bronzeAllergy, 1978
In the vocabulary of daily life the term allergen is most often used to indicate the whole substance able to initiate an allergic reaction, such as certain pollens, moulds, house dust mites, animal dander, cow's milk and other inhalants or food items known to trigger immediate or late, hypersensitivity reactions.
Kjell Aas
openalex   +4 more sources

Allergen nomenclature* [PDF]

open access: bronzeJournal of Allergy and Clinical Immunology, 1988
SummaryThis article presents a nomenclature system for allergens which has been officially recommended by the International Union of Immunological Societies (IUIS). The nomenclature is based on proposals of the IUIS Sub‐Committee for Allergen Nomenclature and is applicable to highly purified, well‐characterized allergens and to non‐purified or ...
David G. Marsh   +4 more
openalex   +4 more sources

Allergen-Specific Antibodies Regulate Secondary Allergen-Specific Immune Responses

open access: yesFrontiers in Immunology, 2019
Immunoglobulin E (IgE)-associated allergy is the most common immunologically-mediated hypersensensitivity disease. It is based on the production of IgE antibodies and T cell responses against per se innocuous antigens (i.e., allergens) and subsequent ...
Julia Eckl-Dorna   +9 more
doaj   +2 more sources

A systematic review and economic evaluation of subcutaneous and sublingual allergen immunotherapy in adults and children with seasonal allergic rhinitis [PDF]

open access: yesHealth Technology Assessment, 2013
Background: Severe allergic rhinitis uncontrolled by conventional medication can substantially affect quality of life. Immunotherapy involves administering increasing doses of a specific allergen, with the aim of reducing sensitivity and symptomatic ...
A Meadows   +7 more
doaj   +2 more sources

Comparison of the Immune Responses to Different Formulations of BC02-Adjuvanted HPV Types 16 and 18 Bivalent Vaccines in Mice

open access: yesVaccines, 2023
To achieve maximum efficacy, vaccines, such as subunit, recombinant, and conjugate vaccines, necessitate the incorporation of immunostimulators/adjuvants.
Junli Li   +7 more
doaj   +1 more source

Novel BC02 Compound Adjuvant Enhances Adaptive and Innate Immunity Induced by Recombinant Glycoprotein E of Varicella-Zoster Virus

open access: yesVaccines, 2022
Both adaptive and innate immunity responses are necessary for the efficient elimination of different pathogens. However, the magnitude, quality and desired type of immune response specific to the co-administered antigen is largely determined by adjuvants.
Junli Li   +6 more
doaj   +1 more source

Impact of oligomerization on the allergenicity of allergens

open access: yesClinical and Molecular Allergy, 2022
AbstractType I hypersensitivity (allergic reaction) is an unsuitable or overreactive immune response to an allergen due to cross-link immunoglobulin E (IgE) antibodies bound to its high-affinity IgE receptors (FcεRIs) on effector cells. It is needless to say that at least two epitopes on allergens are required to the successful and effective cross ...
Amin Moradi Hasan-Abad   +5 more
openaire   +3 more sources

The role of allergen‐specific IgE, IgG and IgA in allergic disease

open access: yesAllergy. European Journal of Allergy and Clinical Immunology, 2021
Immunoglobulin E (IgE)‐mediated allergy is the most common hypersensitivity disease affecting more than 30% of the population. Exposure to even minute quantities of allergens can lead to the production of IgE antibodies in atopic individuals.
M. Shamji   +6 more
semanticscholar   +1 more source

Enhanced Potency and Persistence of Immunity to Varicella-Zoster Virus Glycoprotein E in Mice by Addition of a Novel BC02 Compound Adjuvant

open access: yesVaccines, 2022
Herpes zoster (HZ) is one of two distinct syndromes caused by Varicella-zoster virus (VZV). A primary infection with VZV causes varicella in susceptible young children.
Junli Li   +4 more
doaj   +1 more source

Past, Present and Future of Bacillus Calmette-Guérin Vaccine Use in China

open access: yesVaccines, 2022
The BCG vaccine is prepared from a weakened strain of Mycobacterium bovis (M. bovis), a bacterium closely related to Mycobacterium tuberculosis (MTB), which causes tuberculosis (TB).
Junli Li   +4 more
doaj   +1 more source

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