Results 81 to 90 of about 13,427 (242)

Characterization of Human Group 9 Innate Lymphoid Cells in Response to Allergen Immunotherapy in Patients With Allergic Rhinitis

open access: yesAllergy, EarlyView.
We aimed to report the existence and profile of group 9 innate lymphoid cells (ILC9s). Overall, ILC9 proportions in AR patients show differences compared to healthy subjects and responder SCIT patients. IL‐9 expression decreases after siRNA inhibition of Bach2 suggesting Bach2 could display as a transcription factor of ILC9.
Ya‐Qi Peng   +11 more
wiley   +1 more source

Component-resolved evaluation of the content of major allergens in therapeutic extracts for specific immunotherapy of honeybee venom allergy

open access: yesHuman Vaccines & Immunotherapeutics, 2017
Allergen-specific immunotherapy is the only curative treatment of honeybee venom (HBV) allergy, which is able to protect against further anaphylactic sting reactions.
Simon Blank   +10 more
doaj   +1 more source

Autoclaved Peanuts Exhibit Reduced Immunoglobulin E Binding and Improved Oral Tolerability

open access: yesAllergy, EarlyView.
This study evaluates the effects of heat and pressure autoclaving on peanut proteins, IgE binding, and oral tolerability. Heat and pressure autoclaving breaks down peanut proteins and allergens, contributing to reduced peanut‐specific IgE binding. Autoclaved peanuts are associated with decreased skin test reactivity and greater oral tolerability in ...
Casey G. Cohen   +17 more
wiley   +1 more source

Early Risk Assessment and Recognition of Allergies in Children: Rationale, Methodology, and Proposed Algorithms

open access: yesAllergy, EarlyView.
ABSTRACT Background Atopic diseases—including atopic dermatitis (AD), food allergy (FA), allergic rhinitis (AR), and asthma—are the most common chronic conditions in childhood and adolescence, affecting up to 30% of the global population. In Germany alone, more than 2.1 million children and adolescents are affected.
E. Hamelmann   +13 more
wiley   +1 more source

Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side

open access: yesAllergy, EarlyView.
ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm   +9 more
wiley   +1 more source

Expert consensus on hypodermic care for allergen-specific immunotherapy

open access: yesAllergy Medicine
Objective: To develop an expert consensus on subcutaneous injection for allergen-specific immunotherapy. Methods: Relevant domestic and international literature was reviewed, and nursing experts experienced in subcutaneous injection of allergen-specific ...
Wang Qing   +9 more
doaj   +1 more source

Microarrayed Allergen Molecules Distinguish IgE Sensitisation to Blomia tropicalis and Dermatophagoides pteronyssinus

open access: yesAllergy, EarlyView.
This study established a microarray containing a representative panel of purified Blo t and Der p allergens for the identification of patients sensitised to Blo t and/or Der p. Results indicate that the microarray based on Blo t and Der p allergens is a useful tool for the identification of Blo t‐ and/or Der p‐sensitised patients. The microarray may be
Nishelle Dsouza   +16 more
wiley   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

open access: yesAllergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter   +20 more
wiley   +1 more source

Allergen specific immunotherapy attenuates allergic rhinitis clinical manifestations

open access: yesМедицинская иммунология
The prevalence of allergic diseases, including rhinitis and allergic asthma, is increasing in the modern world based on the Hygiene theory. Avoidance of allergens and using drugs to relieve clinical symptoms in these patients are not sufficient and ...
S. A. Hashemi Moghaddam   +4 more
doaj   +1 more source

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