Cytokine profile in childhood asthma
Journal of Medical Science, 2022 Childhood asthma is a chronic airway disease, which pathogenesis is markedly heterogeneous–with multiple phenotypes defining visible characteristics and endotypes defining molecular mechanisms.
Joanna Matysiak +7 more
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Airway responses and inflammation in subjects with asthma after four days of repeated high-single-dose allergen challenge [PDF]
, 2012 Background: Both standard and low-dose allergen provocations are an established tool in asthma research to improve our understanding of the pathophysiological mechanism of allergic asthma.
Rose, Markus A. +5 more
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The future outlook on allergen immunotherapy in children: 2018 and beyond. [PDF]
, 2018 Allergen immunotherapy (AIT) is the only currently available immune-modifying and aetiological treatment for patients suffering from IgE-mediated diseases.
Arasi S, Corsello G, Pajno GB, Villani A
core +2 more sources
Effect of the Strawberry Genotype, Cultivation and Processing on the Fra a 1 Allergen Content [PDF]
, 2018 Birch pollen allergic patients show cross-reactivity to vegetables and fruits, including strawberries (Fragaria × ananassa). The objective of this study was to quantify the level of the Fra a 1 protein, a Bet v 1-homologous protein in strawberry fruits
Kock, V. +4 more
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Development of a Sandwich ELISA to Measure Exposure to Occupational Cow Hair Allergens [PDF]
, 2011 Background: Cow hair and dander are important inducers of occupational allergies in cattle-exposed farmers. To estimate allergen exposure in farming environments, a sensitive enzyme immunoassay was developed to measure cow hair allergens.
Angelika Flagge +36 more
core +1 more source
Climate change, aeroallergens, and the aeroexposome
Environmental Research Letters, 2021 Allergic diseases are a major public health problem globally and are increasing. The impacts of climate change on aeroallergens such as pollen and fungal spores and allergic respiratory diseases such as allergic asthma and allergic rhinitis have been ...
Paul J Beggs
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Frontiers in Genetics, 2021 Environmental exposures have been linked to increased asthma risk, particularly during pregnancy and in early life. Here we use a mouse model of allergic lung disease to examine the effects of pre- and perinatal house dust mite (HDM) allergen exposure on
Jairus C. Pulczinski +8 more
doaj +1 more source
Sensitization profiles to purified plant food allergens among pediatric patients with allergy to banana. [PDF]
, 2011 Banana fruit allergy is well known, but neither immunoglobulin E recognition patterns to purified plant food allergens nor true prevalences of putative banana allergens have been established. This study aimed to characterize β-1,3-glucanase and thaumatin-
Bobolea, Irina +7 more
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Regulation and directed inhibition of ECP production by human neutrophils
Frontiers in Immunology, 2022 BackgroundNeutrophils are involved in the pathophysiology of allergic asthma, where the Eosinophil Cationic Protein (ECP) is a critical inflammatory mediator.
Antonio Vega-Rioja +18 more
doaj +1 more source
Long-term effects of allergen sensitization and exposure in adult asthma: a prospective study. [PDF]
, 2009 BACKGROUND: : We investigated the effects of sensitization and exposure to common domestic allergens on longitudinal changes in lung function and bronchial hyperresponsiveness. METHODS: : Subjects attended 2 visits that were 4 years apart.
Adnan Custovic +30 more
core +1 more source