Results 261 to 270 of about 256,449 (346)

Circulating Type 2 Memory B Cell Frequency Is a Biomarker for Allergen Immunotherapy Efficacy in Patients With Allergic Rhinitis

Allergy, EarlyView.
Yue Ma, Shuying Li, Lei Ye, Lin Qiu, Jiayu Wu, Jiaying Li, Xian Feng, Wei Qian, Xiangping Yang, Huabin Li, Hongfei Lou   +10 more
wiley   +1 more source

Structural Basis for Trivalent Cross‐Linking of a Patient‐Derived IgE Antibody by the Major Peanut Allergen Ara h 2.0201

Allergy, EarlyView.
Graphical The crystal structure of a major peanut allergen Ara h 2.0201 in a complex with a human‐derived IgE Fab fragment has been determined. The immunocomplex shows the trivalent binding of Fabs, creating a cross‐linked structure effective in the formation of large complexes on the surface of effector cells. Hydroxylation of proline has implications
Tarja Parkkinen, Heidi Heiniluoto, Janne Jänis, Kristiina Takkinen, Juha Rouvinen   +4 more
wiley   +1 more source

The Relation Between Diet and Allergen Concentrations in Breast Milk ; Ovalbumin Concentrations and Lactoferrin Levels in Breast Milk

, 2013
M. Hara, Shunji Hasegawa, Tomoyo Matsubara, Koichi Yamaguchi, Nozomi Momose, Susumu Furukawa   +5 more
openalex   +1 more source

Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema

Allergy, EarlyView.
This study performed an unbiased molecular profiling of CHE patients across diverse etiologies to identify shared pathogenic drivers and evaluate the impact of IL‐4Rα blockade via dupilumab over 16 weeks. CHE shows a mixed immune signature involving type 1, 2, and 3 pathways with features of atopic dermatitis and psoriasis.
Perrine Gery, Rüçhan Ekren, Emilie Bérard, Aurélie Du‐Thanh, Hugo Rimet, Fatma Jendoubi, Vanina Lenief, Nadia Raison‐Peyron, Amel Bouznad, Maria P. Konstantinou, Jonathan Rioual, Lilian Basso, Juliette Mouiren, Manon Boussier, Brigitte Milpied, Cristina Bulai Livideanu, Louise Jaulent, Florence Hacard, Marine A. Lefevre, Audrey Nosbaum, Julien Seneschal, Marc Vocanson, Carle Paul, Nicolas Gaudenzio, Marie Tauber, on behalf of the French Atopic Dermatitis Network from de GREAT Research group   +25 more
wiley   +1 more source

Eosinophilic esophagitis in Colombian children: relationship between food allergens, symptoms and endoscopic findings. [PDF]

BMJ Paediatr Open
Higuera Carrillo M, Carias Domínguez AM, Gonzalez Rozo N, Vera Chamorro JF, Riveros López JP, Ortiz-Piedrahita C, Cuadros Mendoza CA, Peña Hernández S, Velez-Tirado N, Moreno Serrano CA, Calderón-Guerrero OG, Medina Monroy FA, Prada Rey A, Higuera J, Contreras Ramirez MM, Timossi CM, Vasquez-Hoyos P, Camacho-Cruz J, Daza-Carreño W.   +18 more
europepmc   +1 more source

A One‐Strength Dose Escalation Regimen for Birch Pollen SCIT Is Safe and Tolerable in Children, Adolescents, and Adults

Allergy, EarlyView.
This study evaluated safety and tolerability of birch pollen SCIT during dose escalation with a new One‐Strength regimen (3 injections, Strength B) compared to the Standard regimen (7 injections, Strengths A and B) in patients aged 5–65 years. Safety and tolerability were comparable between the two regimens in adults, adolescents, and adolescents, as ...
Marek Jutel, Ludger Klimek, Michael Gerstlauer, Dana Troyke, Kristina Duwensee, Christian Vogelberg   +5 more
wiley   +1 more source

Bioengineering Interventions to Enhance the Capacity of the Gut Microbiota in Controlling Food Allergies. [PDF]

Life (Basel)
Kumar M, Nalla S, Tripathy JN, Shakya AK.   +3 more
europepmc   +1 more source

Autosomal Dominant Hyper‐IgE Syndrome Patients Retain IL10‐Producing preTh17‐Cells That Are Activated by Opportunistic Pathogens and Support IgE Production

Allergy, EarlyView.
IL‐10 producing CCR6+Th‐cells are central memory T‐cells that express ROR‐γt and differentiate to Th17‐cells via an autocrine loop of STAT3‐activating cytokines (preTh17). STAT3‐deficient AD‐HIES patients lack Th17‐ and Tfh17‐cells but retain preTh17‐ and Th1/17‐cells.
Giorgia Moschetti, Chiara Vasco, Francesca Clemente, Paola Larghi, Sara Maioli, Edoardo Scarpa, Elena Carelli, Nadia Pulvirenti, Maria Lucia Sarnicola, Mariacristina Crosti, Manal Bel Imam, Willem van de Veen, Loris Rizzello, Sergio Abrignani, Lucia A. Baselli, Rosa Maria Dellepiane, Maria Carrabba, Giovanna Fabio, Jens Geginat   +18 more
wiley   +1 more source

Identifying microbial protease allergens through protein language model-guided homology. [PDF]

Cell Syst
Thurimella K, Wu E, Li C, Graham DB, Owens RM, Plichta DR, Sokol CL, Xavier RJ, Bacallado S.   +8 more
europepmc   +1 more source

Algorithms in Allergy: Molecular Allergology in the Context of Animal Allergy

Allergy, EarlyView.
Christiane Hilger, Bulent E. Sekerel, Marianne van Hage, Wolfgang Hemmer, Jon R. Konradsen   +4 more
wiley   +1 more source