Results 51 to 60 of about 218,022 (295)

Enhanced Immune Responses in Mice by Combining the Mpox Virus B6R-Protein and Aluminum Hydroxide-CpG Vaccine Adjuvants

Vaccines
Novel adjuvants and innovative combinations of adjuvants (Adjuvant Systems) have facilitated the development of enhanced and new vaccines against re-emerging and challenging pathogenic microorganisms.
Junli Li, Xiaochi Li, Jiaxin Dong, Jiazheng Wei, Xiaonan Guo, Guozhi Wang, Miao Xu, Aihua Zhao   +7 more
doaj   +1 more source

Sublingual allergen immunotherapy with a liquid birch pollen product in patients with seasonal allergic rhinoconjunctivitis with or without asthma [PDF]

, 2019
Background: Sublingual allergen immunotherapy (SLIT) has been demonstrated to be both clinically efficacious and safe. However, in line with the current regulatory guidance from the European Medicines Agency, allergen immunotherapy (AIT) products must ...
Bachert, Claus, Boot, Johan D, de Kam, Pieter-Jan, Džupinová, Mária, Klimek, Ludger, Kuna, Piotr, Opstelten, Dirk Jan E, Panzner, Petr, Pfaar, Oliver, van Nimwegen, Maroesja J, Yu, Donghui   +10 more
core   +2 more sources

Dosing Interval Extension of Dupilumab in CRSwNP: Five‐Year Real World Outcomes

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent, often Type 2‐mediated inflammatory disease that markedly impairs quality of life. While dupilumab provides rapid improvement, there is limited evidence on long‐term outcomes beyond 2 years, and the clinical impact of dosing‐interval extension remains unclear.
Nicholas J. Campion, Dioni‐Pinelopi Petsiou, Florian C. Fally, Karina Berbalk, Noah F. Melamed, Aldine Tu, Christina Morgenstern, Fana Alem Kidane, Mohammed Zghaebi, Linda Liu, Minghao Pan, Tina J. Bartosik, Victoria Stanek, Katarina Gangl, Julia Eckl‐Dorna, Sven Schneider   +15 more
wiley   +1 more source

Molecular profile of sensitization in subjects with short occupational exposure to latex [PDF]

, 2015
Objectives: We examined the prevalence of latex allergy in subjects with occupational exposure to latex allergens for less than 5 years, determining the disease spectrum in symptomatic workers.
Buonanno, Rosaria, Crispino, Vincenzo, DI CARLO, Angelina, Di Domenico, Marina, Feola, Antonia, Giovane, Giancarlo, Lamberti, Monica, Medici, Nicola, Ritonnaro, Chiara, Sannolo, Nicola   +9 more
core   +3 more sources

Allergic Rhinitis Amplifies Asthma Risk in Patients With Chronic Rhinosinusitis: A Large‐Scale Retrospective Cohort Analysis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and allergic rhinitis (AR) are two highly prevalent airway diseases in the United States. While the coexistence of CRS and asthma is well recognized, less is known about the development of new‐onset asthma in CRS, particularly in the context of comorbid AR. This study assessed the impact of CRS and AR on
Austin J. Lee, Mohamad R. Chaaban
wiley   +1 more source

The Diversity in Dust Fungal Spores Concentration at Four Districts of Al-Najaf Environment and their Potential Correlation with Asthma

Journal of Pure and Applied Microbiology, 2019
Fungal spores are biological molecules that are widespread in the indoor and outdoor air. Several types of the very common fungal spores are known as allergens, with the potential to cause respiratory illnesses by increasing the aggravation of asthma and
Noor I. Nasser, Maysoon K. Al-Hadrawi, Salam A. Oleiwi, Ahmed Abdulhasan Mohsin   +3 more
doaj   +1 more source

Regulation of eosinophilia and allergic airway inflammation by the glycan-binding protein galectin-1 [PDF]

, 2016
Galectin-1 (Gal-1), a glycan-binding protein with broad antiinflammatory activities, functions as a proresolving mediator in autoimmune and chronic inflammatory disorders. However, its role in allergic airway inflammation has not yet been elucidated.
Abramoff, Ada G. Blidner, Amrita Rao, Boehme, Gabriel A. Rabinovich, Ge, Ha, He, Idil Bastan, Matsuura, P. Sriramarao, Rabinovich, Savita P. Rao, Sung Gil Ha, Xiao Na Ge, Yana G. Greenberg   +15 more
core   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

RNA vaccines: The dawn of a new age for tuberculosis?

Human Vaccines & Immunotherapeutics
Since 2019, there has been a growing focus on mRNA vaccines for infectious disease prevention, particularly following the emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
Junli Li, Dong Liu, Xiaochi Li, Jiazheng Wei, Weixin Du, Aihua Zhao, Miao Xu   +6 more
doaj   +1 more source

Cigarette smoke exposure facilitates allergic sensitization in mice [PDF]

, 2006
Background Active and passive smoking are considered as risk factors for asthma development. The mechanisms involved are currently unexplained. Objective The aim of this study was to determine if cigarette smoke exposure could facilitate primary allergic
MD Althuis, P Lange, V Siroux, BW Seymour, KB Moerloose, R Piipari, PG Holt, GF Hoyne, A O'garra, JC Kips, O Zetterstrom, R Rumold, K Bowles, RD Hautamaki, K Vermaelen, KY Vermaelen, AI D'hulst, A Bai, KO De Swert, MR Stampfli, C McMenamin, KG Tournoy, M Lovik, S Kawasaki, EC Cates, CL Hofstra, CJ Corrigan, M Cembrzynska-Nowak, SH Cho   +28 more
core   +2 more sources