Results 71 to 80 of about 251,522 (310)

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

open access: yesAdvanced Science, EarlyView.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen   +5 more
wiley   +1 more source

Evolution of standardization of therapeutic and diagnostic allergens produced in Russia

open access: yesАллергология и Иммунология в Педиатрии
Allergen-specific immunotherapy is based on the development of induced tolerance in patients. Natural extracts are most often used as therapeutic allergens worldwide.The article presents new approaches to biological standardization of subcutaneous ...
S. S. Masalskiy   +2 more
doaj   +1 more source

Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma. [PDF]

open access: yes, 2009
The innate immune response of airway epithelial cells to airborne allergens initiates the development of T cell responses that are central to allergic inflammation.
Angkasekwinai, Pornpimon   +14 more
core  

Selective PAR2 Inhibition Attenuates HDM‐Induced Th1/Th2 Responses in Human Epithelial and Murine Models of Allergic Rhinitis and Asthma

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Allergic rhinitis (AR) and asthma are involved in complex interactions between Th1 and Th2 inflammatory pathways. House dust mite (HDM) activates protease‐activated receptor 2 (PAR2) to trigger inflammatory responses, but current treatments often provide inadequate control.
Miran Kang   +8 more
wiley   +1 more source

Gluten Detection by Real-Time PCR: an Alternative for Tracking Processed Foods [PDF]

open access: yesBrazilian Archives of Biology and Technology
This work reports a real-time PCR assay to specifically detect the presence of gluten in complex food matrices and to carry out an in-silico prospection of primers used in scientific research.
Wemerson de Castro Oliveira   +2 more
doaj   +1 more source

The clinical meaning of histamine skin reactivity [PDF]

open access: yes, 2015
The definition of the “atopic state”, i.e. subjects presenting at least one skin wheal with a minimum diameter of 3 mm induced by an allergen skin-prick test (ASPT), is based on the assumption that wheal size depends entirely on the amount of histamine
BARRETO, Mario, RONCHETTI, ROBERTO
core   +1 more source

Cadherin‐26 Facilitates Transepithelial Migration of Eosinophils in Eosinophilic Chronic Rhinosinusitis

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP) is characterized by persistent sinonasal inflammation and marked eosinophilic infiltration. Although the relationship between eosinophils and NP formation has been extensively studied, the mechanisms governing eosinophil transepithelial migration into the nasal mucosa ...
Yeong‐In Jo   +7 more
wiley   +1 more source

Deallergisation trials of pure celery juice and apple-celery juice mixture by oxidation

open access: yesCzech Journal of Food Sciences, 2011
This work aimed to determine if it was possible to eliminate or reduce the content of the Api g1 allergen in celery juice by oxidation, utilising its natural polyphenol oxidase (PPO) content.
Pavla Novotná   +9 more
doaj   +1 more source

Comparison of techno-functional and sensory properties of sponge cakes made with egg powder and different quality of powdered blood products for substituting egg allergen and developing functional food [PDF]

open access: gold, 2022
Tamás Csurka   +8 more
openalex   +1 more source

Development of Artificial Intelligence for Quantitative Assessment of Nasal Inflammatory Cytology in Chronic Rhinitis by Whole‐Slide Images

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinitis (CR) is currently recognized as a syndrome that manifests in different phenotypes. We aimed to establish an artificial intelligence system (quantitative assessment of nasal inflammatory cytology, QANIC) on the basis of whole‐slide images (WSIs) to enable quantitative assessment of nasal inflammatory cells.
Xu Zhang   +9 more
wiley   +1 more source

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