Results 71 to 80 of about 120,561 (245)
Exploring Multi‐Organ Crosstalk via the TissUse HUMIMIC Chip System: Lessons Learnt So Far
ABSTRACT Three‐dimensional (3D) in vitro cell culture models have revolutionized biomedical research by mimicking the complex 3D in vivo environment in the human body. Different types of 3D models have been established, including heterotypic systems such as, organ‐on‐a‐chips which have been further developed into multiorgan‐on‐chip systems that ...
Filsan Ahmed Abokor+5 more
wiley +1 more source
ABSTRACT This article aims to analyze the impact of attention drivers associated with food bottom‐up processes (virtue, vice, and binary choices) on physiological measures (fixation count and fixation duration) of psychological constructs (attention allocation and cognitive processing) of visual attention.
Wagner Junior Ladeira+7 more
wiley +1 more source
Serum levels of Candida-specific IgG(4) antibodies were examined in 66 patients with bronchial asthma, relating to patient age and asthma severity. 1.
Harada, Hideo+7 more
core +1 more source
Enzymatic methodology for truncation of base modified aptamers from 3’‐, 5’‐ or 3’‐ and 5’‐ends suitable also for 5’‐labeling or partially mutated versions, is presented and exemplified on a β‐conglutin aptamer containing indole modifications. A new enzymatic method for truncation of aptamers from 5’‐end has been developed and demonstrated on a newly ...
Marek Ondruš+6 more
wiley +1 more source
Cholesterol-sensing liver X receptors stimulate Th2-driven allergic eosinophilic asthma in mice [PDF]
Introduction: Liver X receptors (LXRs) are nuclear receptors that function as cholesterol sensors and regulate cholesterol homeostasis. High cholesterol has been recognized as a risk factor in asthma; however, the mechanism of this linkage is not known.
De Beuckelaer, Ans+10 more
core +1 more source
RORγt‐APCs: The New Masters of Oral Tolerance
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley +1 more source
Component-Resolved in Vitro Diagnosis in Peach-Allergic Patients [PDF]
BACKGROUND: The in vitro diagnosis of pollen-related food allergy presents low specifi city and reproducibility with many conventional extracts. This can be improved using natural purifi ed allergens, recombinant purifi ed allergens, or both.
Antepara, I.+8 more
core +1 more source
Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model
ABSTRACT The skin constitutes a dynamic interface orchestrating a sophisticated multilayered defense system comprising physical, chemical, immune, and microbial barriers. This review synthesizes current understanding of the structural and functional integration of these barriers, emphasizing their synergistic interactions in maintaining cutaneous ...
Jingjing Xia+4 more
wiley +1 more source
Abstract Gene expression biomarkers have the potential to identify genotoxic and non‐genotoxic carcinogens, providing opportunities for integrated testing and reducing animal use. In August 2022, an International Workshops on Genotoxicity Testing (IWGT) workshop was held to critically review current methods to identify genotoxicants using ...
Roland Froetschl+14 more
wiley +1 more source
Studies of Allergens from Alder Pollen (Alnus Glutinosa). [PDF]
Stig Herbertson+5 more
openalex +1 more source