Results 151 to 160 of about 60,310 (258)

Exposome-driven molecular sensitization signatures in pediatric rhinitis and asthma across Spanish regions. [PDF]

Pediatr Allergy Immunol
Álvaro-Lozano M, Martínez-Cañavate AM, Carballada F, Mesa-Del-Castillo M, Arceo JÁP, Magán CG, Valero CB, Blasco JL, Niño JAM, Pastor GU, González PF, López LM, López-Rodríguez R, Hernández PV, Solano-Galán P, Fernández AEF, González EA, Mazas YA, Martínez MJM, Galán-Díez T, Tortajada-Girbés M, Rivas-Juesas C, de la Losa FP.   +22 more
europepmc   +1 more source

Molecular Allergen Sensitization Profiling in a Large Cohort of Dogs Suspected of Allergic Diseases in the USA: Prevalence and Unsupervised IgE Clustering (2024-2025). [PDF]

Animals (Basel)
Olivry T, Mas-Fontao A.
europepmc   +1 more source

Microarrayed Allergen Molecules Distinguish IgE Sensitisation to Blomia tropicalis and Dermatophagoides pteronyssinus

Allergy, EarlyView.
This study established a microarray containing a representative panel of purified Blo t and Der p allergens for the identification of patients sensitised to Blo t and/or Der p. Results indicate that the microarray based on Blo t and Der p allergens is a useful tool for the identification of Blo t‐ and/or Der p‐sensitised patients. The microarray may be
Nishelle Dsouza, Siratcha Phanthong, Huey‐Jy Huang, Milena Weber, Eszter Sarzsinszky, Petra Zieglmayer, Gabrielle Pauli, Margarete Focke‐Tejkl, Mikhail Tulaev, Nikolina Todorovic, Walter Keller, Thomas Schlederer, Luis Caraballo, Anchalee Tungtrongchitr, Rudolf Valenta, Pongsakorn Tantilipikorn, Susanne Vrtala   +16 more
wiley   +1 more source

Control first, tolerance second: biologics as enablers of allergen immunotherapy in severe allergic asthma. [PDF]

Front Allergy
Jentzsch B, Hoheisel A, Gashynova K, Fähndrich S, Frye BC, Alvarado Castillo JA, Müller S, Cherrez-Ojeda I, Stolz D.   +8 more
europepmc   +1 more source

Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells

Allergy, EarlyView.
We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller, Julia Hambach, Alessa Zoe Schaffrath, Thomas Eden, Sophia Cichutek, Anna Josephine Gebhardt, Natalie Tode, Ronald Maitschke‐Rajasekharan, Philipp Lewe, Sharon Qi, Susanne Witt, Marie Eggers, Nicola M. Tomas, Friedrich Haag, Friedrich Koch‐Nolte, Boris Fehse, Kristoffer Riecken   +16 more
wiley   +1 more source

A Fully Automated Chemiluminescent Immunoassay for Component-Resolved Diagnosis of Pollen Allergy: Validation of Six CHORUS CLIA Assays. [PDF]

Diagnostics (Basel)
Cerutti H, Bianciardi S, Barberini G, Soldatini C, Cartocci A, Bandini T, Tesi G, Brogi A.   +7 more
europepmc   +1 more source

Elevated CO2 and Temperature Alter Grass Pollen's Ability to Modify Transcriptome and Function of the Nasal Epithelium

Allergy, EarlyView.
We exposed human nasal epithelial tissues to pollen from grasses grown under different climate treatments (temperature and CO2). Pollen weakened epithelial tight junctions and altered cytokine‐related gene expression, with similar protein‐level effects.
Tarleena Tossavainen, Tanja Turunen, Maria‐Viola Martikainen, Miisa Kankaanpää, Marjo Malinen, Marjut Roponen   +5 more
wiley   +1 more source

Allergic Rhinitis: From Pathology to Novel Therapeutic Approaches. [PDF]

Biomedicines
Tan S, Yu S.
europepmc   +1 more source

Autosomal Dominant Hyper‐IgE Syndrome Patients Retain IL10‐Producing preTh17‐Cells That Are Activated by Opportunistic Pathogens and Support IgE Production

Allergy, EarlyView.
IL‐10 producing CCR6+Th‐cells are central memory T‐cells that express ROR‐γt and differentiate to Th17‐cells via an autocrine loop of STAT3‐activating cytokines (preTh17). STAT3‐deficient AD‐HIES patients lack Th17‐ and Tfh17‐cells but retain preTh17‐ and Th1/17‐cells.
Giorgia Moschetti, Chiara Vasco, Francesca Clemente, Paola Larghi, Sara Maioli, Edoardo Scarpa, Elena Carelli, Nadia Pulvirenti, Maria Lucia Sarnicola, Mariacristina Crosti, Manal Bel Imam, Willem van de Veen, Loris Rizzello, Sergio Abrignani, Lucia A. Baselli, Rosa Maria Dellepiane, Maria Carrabba, Giovanna Fabio, Jens Geginat   +18 more
wiley   +1 more source

Common Ragweed Allergy Under Global Change Linking Invasion-Driven Aeroallergen Exposure with Molecular Sensitization and Allergic Airway Disease. [PDF]

Life (Basel)
Ferencz-Iepan MA, Ștef L, Lele SF, Morariu FE, Corcionivoschi N, McCleery D, Balta I, Peț I.   +7 more
europepmc   +1 more source