The discovery of potent, selective, and reversible inhibitors of the house dust mite peptidase allergen Der p 1: an innovative approach to the treatment of allergic asthma. [PDF]
Blocking the bioactivity of allergens is conceptually attractive as a small-molecule therapy for allergic diseases but has not been attempted previously.
Anandan C.+56 more
core +2 more sources
Drug and xenobiotic biotransformation in the blood-brain barrier: A neglected issue.
Drug biotransformation is a crucial mechanism for facilitating the elimination of chemicals from the organism and for decreasing their pharmacological activity.
José A.G. Agúndez+5 more
doaj +1 more source
Tus-Ter-lock immuno-PCR assays for the sensitive detection of tropomyosin-specific IgE antibodies [PDF]
Background: The increasing prevalence of food allergies requires development of specific and sensitive tests capable of identifying the allergen responsible for the disease. The development of serologic tests that can detect specific IgE antibodies to allergenic proteins would therefore be highly received.
arxiv +1 more source
Development of a Sandwich ELISA to Measure Exposure to Occupational Cow Hair Allergens [PDF]
Background: Cow hair and dander are important inducers of occupational allergies in cattle-exposed farmers. To estimate allergen exposure in farming environments, a sensitive enzyme immunoassay was developed to measure cow hair allergens.
Angelika Flagge+36 more
core +1 more source
Allergen Peptides, Recombinant Allergens and Hypoallergens for Allergen-Specific Immunotherapy [PDF]
Allergic diseases are among the most common health issues worldwide. Specific immunotherapy has remained the only disease-modifying treatment, but it is not effective in all patients and may cause side effects. Over the last 25 years, allergen molecules from most prevalent allergen sources have been isolated and produced as recombinant proteins.
Christian Lupinek+4 more
openaire +3 more sources
Evaluation of Suspected Cosmetic Induced Facial Dermatoses with the Use of Indian Standard Series and Cosmetic Series Patch Test [PDF]
Introduction: Awareness about skin beauty or cosmetic elegance has received worldwide attention in the present day youth oriented society. Along with careful detailed history and thorough examination patch test is considered cornerstone in diagnosis ...
Madhur Kant Rastogi+4 more
doaj +1 more source
Bee pollen is consumed for its nutritional and pharmacological benefits, but it also contains hazardous allergens which have not been identified. Here, we identified two potential allergens, glutaredoxin and oleosin-B2, in Brassica napus bee pollen using
Shuting Yin+8 more
doaj +1 more source
Predefined domain specific embeddings of food concepts and recipes: A case study on heterogeneous recipe datasets [PDF]
Although recipe data are very easy to come by nowadays, it is really hard to find a complete recipe dataset - with a list of ingredients, nutrient values per ingredient, and per recipe, allergens, etc. Recipe datasets are usually collected from social media websites where users post and publish recipes.
arxiv +1 more source
Allergic Disorders in Africa and Africans: Is it Primarily a Priority? [PDF]
In Africa, the burden of some diseases has been a problem for centuries. The spectrum of African diseases includes allergies, infections, nutritional deficiencies, and natural disasters.
Adams+80 more
core +1 more source
The protein/peptide composition of five beer kinds, including two experimental beer-like products brewed with einkorn (Triticum monococcum), a beer labeled as “gluten-free,” a traditional all-barley malt and a wheat (T.
Valentina Spada+6 more
doaj +1 more source