Morphological Sinus Features and Chronic Rhinosinusitis Risk: A Radiomics Study
ABSTRACT Objectives Anatomical factors of the sinuses significantly impact the progression of chronic rhinosinusitis (CRS). This study aims to investigate the correlation between morphological sinus features and the risk of CRS onset to provide evidence‐based support for clinical management.
Song Luo +4 more
wiley +1 more source
Inflammatory Shift in Chronic Rhinosinusitis Amidst Guangzhou's Urbanization (2000–2018)
ABSTRACT Background Chronic rhinosinusitis (CRS) exhibits temporal and geographic diversity in pathological endotypes with progressive eosinophilic infiltration, while the underlying causes remain unclear. Current pathological endotypes determination relies on mean cell count per high‐power field, requiring accuracy optimization.
Ning Kang +16 more
wiley +1 more source
Corrigendum to "PPAR-γ suppresses macrophage senescence and allergic airway inflammation through controlling lipid metabolic pathways" [EBioMedicine 126 (2026) 106226]. [PDF]
Gu W +8 more
europepmc +1 more source
ABSTRACT Background The prevalence of allergic rhinitis (AR) and asthma (AS) comorbidity (AR + AS) is increasing and is associated with severe allergic symptoms. The impact of cat dander sensitization on AR + AS remains unclear. Methods In this retrospective study, 1154 patients with AR alone and 213 patients with AR + AS were enrolled at the Third ...
Wei‐Hao Wang +5 more
wiley +1 more source
PPAR-γ suppresses macrophage senescence and allergic airway inflammation through controlling lipid metabolic pathways. [PDF]
Gu W +8 more
europepmc +1 more source
ABSTRACT Objective Budesonide is a corticosteroid with unique pharmacokinetic and pharmacodynamic properties that has been a frontline treatment for patients with allergic rhinitis (AR) and chronic rhinosinusitis (CRS) since the 1990s. As research on budesonide continues to produce new insights, our aim was to synthesize recent investigations and ...
David W. Kennedy +2 more
wiley +1 more source
Subcutaneous immunotherapy-induced IgG1 suppresses allergic airway inflammation through FcγRIIb-mediated inhibition of group 2 innate lymphoid cell proliferation. [PDF]
Matsuda M +8 more
europepmc +1 more source
Immune Clues to Sinus Blues: Linking Biomarkers to Radiologic Score of Rhinosinusitis
ABSTRACT Background Chronic rhinosinusitis (CRS) is a prolonged inflammatory condition of the nasal and paranasal sinuses that significantly affects quality of life. This study examines the relationship between CRS severity (based on Lund‐Mackay [LM] scores), osteitis, and systemic inflammatory markers, including neutrophil‐to‐lymphocyte ratio (NLR ...
Lubna Khreesha +10 more
wiley +1 more source
Investigations of immune responses in different mouse models of allergic asthma [PDF]
Kirstein, Frank
core +1 more source

