Effect of Dupilumab on Airway Inflammation in Patients With Persistent Asthma
EXPEDITION (NCT02573233) assessed the effects of dupilumab on airway inflammation in patients with persistent asthma using bronchoscopy and gene expression analysis. Dupilumab showed no appreciable effect on inflammatory cell types in biopsies or BALF samples.
Michael E. Wechsler +22 more
wiley +1 more source
Extracellular vesicles derived from lung M2 macrophages enhance group 2 innate lymphoid cells function in allergic airway inflammation. [PDF]
Lv K +6 more
europepmc +1 more source
Differential Effects of Benralizumab and Mepolizumab on Pro‐Resolving Mediators
Allergy, EarlyView.
Jaime Bernaola +14 more
wiley +1 more source
Therapeutic effects of a combination of <i>Chinese quince</i> and <i>Saururus chinensis</i> extract on allergic airway inflammation in an ovalbumin-induced asthma mouse model. [PDF]
Lee HJ +9 more
europepmc +1 more source
Mechanism differences in the start time of sublingual immunotherapy in a mouse allergic airway inflammation model. [PDF]
Saito A +13 more
europepmc +1 more source
Tetraspanin CD53 Promotes Inflammation but Restrains Mucus Production in a Mouse Model of Allergic Airway Inflammation. [PDF]
Hsu AT +16 more
europepmc +1 more source
Heat-killed Akkermansia muciniphila ameliorates allergic airway inflammation in mice. [PDF]
Yoon SA +10 more
europepmc +1 more source
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Several genes, including ADAM33, DPP10, PHF11, GPRA, and TIM-1, have been implicated in the pathogenesis and susceptibility to atopy and asthma. Advances have been made in defining the mechanism for the control of allergic airway inflammation in response to inhaled antigens.
Devendra K, Agrawal, Arpita, Bharadwaj
openaire +2 more sources

