Background Many infants born at less than 34 weeks of gestational age will require resuscitation in the delivery suite. Yet, different resuscitation techniques are specified in different national guidelines, likely reflecting a limited evidence base. One
Katie A. Hunt +4 more
doaj +1 more source
Toll-Like Receptor Agonists as Adjuvants for Allergen Immunotherapy
Toll-like receptors (TLRs) are essential components of innate immunity and provide defensive inflammatory responses to invading pathogens. Located within the plasma membranes of cells and also intracellular endosomes, TLRs can detect a range of pathogen ...
Max E. Kirtland +6 more
doaj +1 more source
INTRODUCTION: Asthma is a prevalent disease that can cause different clinical features due to various underlying mechanisms. Detecting different types of asthma is important in disease management.
Ali Can
doaj +1 more source
Allergic fetal priming leads to developmental, behavioral and neurobiological changes in mice. [PDF]
The state of the mother's immune system during pregnancy has an important role in fetal development and disruptions in the balance of this system are associated with a range of neurologic, neuropsychiatric and neurodevelopmental disorders ...
Ashwood, P +4 more
core +2 more sources
Recent advances in understanding rhinovirus immunity [version 1; referees: 4 approved]
Rhinoviruses are the most common cause of upper respiratory tract infections. However, they can induce exacerbations of chronic obstructive pulmonary disease and asthma, bronchiolitis in infants, and significant lower respiratory tract infections in ...
Spyridon Makris, Sebastian Johnston
doaj +1 more source
Emerging Roles of Platelets in Allergic Asthma
Allergic asthma is a complex chronic inflammatory disease of the airways, driven by Th2 immune responses and characterized by eosinophilic pulmonary inflammation, airway hyperresponsiveness, excessive mucus production, and airway remodeling. Overwhelming
Ming Yue +4 more
doaj +1 more source
Transcriptional Analysis of the Human IgE-Expressing Plasma Cell Differentiation Pathway
IgE is secreted by plasma cells (PCs) and is central to allergic disease. Using an ex vivo tonsil B cell culture system, which mimics the Th2 responses in vivo, we have recently characterized the development pathway of human IgE-expressing PCs.
Faruk Ramadani +7 more
doaj +1 more source
Prevalence and comorbidity of asthma, allergic rhinitis and eczema among school children in Republic of Srpska: A cross-sectional study [PDF]
Introduction/Objective. The incidence of comorbidity of asthma and allergic rhinitis was one of the reasons for changing guidelines for the treatment of asthma and allergic rhinitis.
Domuz Sanela +2 more
doaj +1 more source
Prevalence of Allergic and Non-allergic Asthma in Kumaun Region of Uttarakhand, India: A Cross-sectional Study [PDF]
Introduction: Asthma is a heterogenic disease, commonly divided into allergic and nonallergic asthma. It affects people of all age group and is associated with impaired lung function.
POONAM KUMARI +2 more
doaj +1 more source
The discovery of potent, selective, and reversible inhibitors of the house dust mite peptidase allergen Der p 1: an innovative approach to the treatment of allergic asthma. [PDF]
Blocking the bioactivity of allergens is conceptually attractive as a small-molecule therapy for allergic diseases but has not been attempted previously.
Anandan C. +56 more
core +2 more sources

