Results 71 to 80 of about 221,385 (308)

The effectiveness of target therapy in patients with severe allergic asthma [PDF]

Терапевтический архив, 2019
The purpose of study was to analyze own clinical experience and assess the effectiveness in treatment of severe very poorly controlled allergic asthma patients with omalizumab.
O V Skorokhodkina, A R Valeeva, A V Luntsov, V A Pozdnyak   +3 more
doaj   +1 more source

Evaluation of the role of rs2227983 polymorphism of EGFR gene in the development of allergic asthma

Туберкулез и болезни лёгких, 2022
The objective of the study: to study rs2227983 polymorphism of EGFR gene in patients with allergic asthma and healthy individuals.Subjects and Methods. 179 patients suffering from allergic asthma were included in the study.
A. B. Аveryanov, I. I. Cherkashina, S. Yu. Nikulina, E. Yu. Kuznetsova, V. N. Maksimov   +4 more
doaj   +1 more source

Interactions between mast cells and smooth muscle in asthma models [PDF]

, 2014
Allergic asthma is the major phenotype of asthma and is characterized by specific responses to allergens as well as airway hyperresponsiveness (AHR), inflammation and remodelling.
Sjöberg, Lisa
core   +1 more source

CRISPLD2 Attenuates Intervertebral Disc Degeneration by Suppressing Oxidative Stress‐Induced Ferroptosis through the miR‐548I‐IL17A Axis

Advanced Science, EarlyView.
This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi, Fudong Li, Tianyi Zhao, Kaiqiang Sun, Danying Zhang, Chen Yan, Ximing Xu, Jingchuang Sun, Xulin Hu, Xin Yong, Jiangang Shi, Yuan Wang   +11 more
wiley   +1 more source

Leptin, Obesity and IgE in patients with Asthma and Allergic Rhinitis

Diyala Journal of Medicine, 2019
Background: Asthma is a chronic inflammatory disease of the respiratory airways with a worldwide prevalence. This study was performed to evaluate the role of leptin on asthma and /or allergic rhinitis, and to study asthma-obesity-leptin relationship.
Adnan Hasan Alwan , Amina Hamed Ahmed Alobaidi , Abdulghani Mohamed Alsamarai   +2 more
doaj   +2 more sources

Transcriptomic analysis reveals diverse gene expression changes in airway macrophages during experimental allergic airway disease [version 1; peer review: 2 approved]

Wellcome Open Research, 2020
Background: Airway macrophages (AMs) are the most abundant leukocytes in the healthy airway lumen and have a highly specialised but plastic phenotype that is governed by signals in the local microenvironment.
William J. Branchett, Anne O'Garra, Clare M. Lloyd   +2 more
doaj   +1 more source

Allergic Disorders in Africa and Africans: Is it Primarily a Priority? [PDF]

, 2010
In Africa, the burden of some diseases has been a problem for centuries. The spectrum of African diseases includes allergies, infections, nutritional deficiencies, and natural disasters.
Adams, Araujo, Araujo, Asmah, Breman, Brugman, Butler, Carvalho, Chaisson, Cooper, Cooper, Cooper, Cullinan, Dagoye, Dagoye, Du Toit, Erasto Vitus Mbugi, Estmbale, Gadermaier, Grant, Jaffu Othniel Chilongola, Jeannin, Jeebhay, Jeebhay, Kamradt, Linneberg, Linneberg, Lopata, Lynch, Lynch, Madsen, Marshall, Matricardi, Matricardi, Mercer, Modjarrad, Moore, Motala, Ndiaye, Nicolaou, Nyan, Obeng, Obihara, Obihara, Obihara, Obihara, Obihara, Obihara, Okano, Pacifico, Palyvos, Pawankar, Platts-Mills, Potter, Potter, Potter, Potter, Rauter, Riedler, Scrivener, Sibanda, Sibanda, Steinman, Thyssen, Tohon, van den Biggelaar, van den Biggelaar, van den Biggelaar, van der Kleij, van Niekerk, Van Niekerk, Veien, Veien, Vergara, Weinberg, Westritschnig, Wuthrich, Yazdanbakhsh, Yazdanbakhsh, Yazdanbakhsh, Zar   +80 more
core   +1 more source

Antibody‐Empowered Nanomedicine for Precise Biomedical Applications

Advanced Science, EarlyView.
This review explores strategies for functionalizing nanoparticles with antibodies to construct antibody‐empowered nanomedicine. It discusses the classification of these nanomedicines based on antibody structure, with a specific focus on their biomedical applications in diagnostics, bioimaging, and therapeutics for various diseases.
Chen Chen, Xinglin Chen, Zhenhao Gao, Meng Sun, Yaozong Yu, Fang Lv, Qiujun Wang, Jinfeng Zhang   +7 more
wiley   +1 more source

Domestic exposure to irritant cleaning agents and asthma in women

Environment International, 2020
An adverse role of frequent domestic use of cleaning agents, especially in spray form, on asthma has been reported. However, sparse studies have investigated respiratory health effects of chronic domestic exposure to irritant cleaning agents.
Pierre Lemire, Orianne Dumas, Sébastien Chanoine, Sofia Temam, Gianluca Severi, Marie-Christine Boutron-Ruault, Jan-Paul Zock, Valérie Siroux, Raphaëlle Varraso, Nicole Le Moual   +9 more
doaj   +1 more source

A systematic review and economic evaluation of subcutaneous and sublingual allergen immunotherapy in adults and children with seasonal allergic rhinitis [PDF]

, 2013
© Queen’s Printer and Controller of HMSO 2013Severe allergic rhinitis uncontrolled by conventional medication can substantially affect quality of life. Immunotherapy involves administering increasing doses of a specific allergen, with the aim of reducing
Barton, P, Dretzke, J, Fry-Smith, A, Huissoon, A, Kaambwa, B, Meadows, A, Meads, C, Novielli, N   +7 more
core   +1 more source