Results 11 to 20 of about 163,346 (259)

Short-Chain Fatty Acids Calibrate RARα Activity Regulating Food Sensitization

open access: yesFrontiers in Immunology, 2021
Gut-microbiota dysbiosis links to allergic diseases. The mechanism of the exacerbation of food allergy caused by gut-microbiota dysbiosis remains unknown. Regulation of retinoic acid receptor alpha (RARα) signaling is critical for gut immune homeostasis.
Xiefang Yuan   +9 more
doaj   +1 more source

Persistent Airway Hyperresponsiveness Following Recovery from Infection with Pneumonia Virus of Mice

open access: yesViruses, 2021
Respiratory virus infections can have long-term effects on lung function that persist even after the acute responses have resolved. Numerous studies have linked severe early childhood infection with respiratory syncytial virus (RSV) to the development of
Ajinkya R. Limkar   +4 more
doaj   +1 more source

Respiratory Epithelial Cells Respond to Lactobacillus plantarum but Provide No Cross-Protection against Virus-Induced Inflammation

open access: yesViruses, 2020
Virus-induced inflammation plays a critical role in determining the clinical outcome of an acute respiratory virus infection. We have shown previously that the administration of immunobiotic Lactobacillus plantarum (Lp) directly to the respiratory tract ...
Eric Mai   +5 more
doaj   +1 more source

Autophagy Modulators From Chinese Herbal Medicines: Mechanisms and Therapeutic Potentials for Asthma

open access: yesFrontiers in Pharmacology, 2021
Asthma has become a global health issue, suffering more than 300 million people in the world, which is a heterogeneous disease, usually characterized by chronic airway inflammation and airway hyperreactivity.
Yun Zhang   +13 more
doaj   +1 more source

Recent advances in mast cell activation and regulation [version 1; peer review: 2 approved]

open access: yesF1000Research, 2020
Mast cells are innate immune cells that intersect with the adaptive immunity and play a crucial role in the initiation of allergic reactions and the host defense against certain parasites and venoms.
Hwan Soo Kim   +3 more
doaj   +1 more source

Immunoglobulin E-Dependent Activation of Immune Cells in Rhinovirus-Induced Asthma Exacerbation

open access: yesFrontiers in Allergy, 2022
Acute exacerbation is the major cause of asthma morbidity, mortality, and health-care costs. Respiratory viral infections, particularly rhinovirus (RV) infections, are associated with the majority of asthma exacerbations. The risk for bronchoconstriction
Toshiaki Kawakami   +4 more
doaj   +1 more source

Basophils and allergic inflammation [PDF]

open access: yesJournal of Allergy and Clinical Immunology, 2013
Basophils were discovered by Paul Ehrlich in 1879 and represent the least abundant granulocyte population in mammals. The relative rarity of basophils and their phenotypic similarities with mast cells resulted in this cell lineage being historically overlooked, both clinically and experimentally.
Mark C, Siracusa   +3 more
openaire   +2 more sources

The development of allergic inflammation [PDF]

open access: yesNature, 2008
Allergic disorders, such as anaphylaxis, hay fever, eczema and asthma, now afflict roughly 25% of people in the developed world. In allergic subjects, persistent or repetitive exposure to allergens, which typically are intrinsically innocuous substances common in the environment, results in chronic allergic inflammation. This in turn produces long-term
Stephen J, Galli   +2 more
openaire   +2 more sources

Cadmium induces apoptosis of human granulosa cell line KGN via mitochondrial dysfunction-mediated pathways

open access: yesEcotoxicology and Environmental Safety, 2021
Cadmium (Cd) is an important industrial and environmental pollutant, which is closely correlated with female infertility. Although Cd-induced developmental disorders of human ovarian follicles have been widely reported, the underlying mechanisms remain ...
Guofeng Xu   +4 more
doaj   +1 more source

Bacterial Quorum Sensing Molecules Promote Allergic Airway Inflammation by Activating the Retinoic Acid Response

open access: yesiScience, 2020
Summary: IgE and IgG1 production in the type 2 immune response is the characteristic feature of an allergic reaction. However, whether bacterial molecules modulate IgE and IgG1 production remains obscure.
Renlan Wu   +8 more
doaj   +1 more source

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