Mini-review: The health benefits and applications of allicin [PDF]
Frontiers in PharmacologyGarlic is a perennial plant with a long history of cultivation and medicinal use. As a valuable food additive and spice, garlic contains many nutrients and chemicals. Allicin is a key bioactive organosulfur metabolite derived from garlic bulbs. In recent
Ke-Qian Chen +3 more
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Allicin: Chemistry and Biological Properties
Molecules, 2014 Allicin (diallylthiosulfinate) is a defence molecule from garlic (Allium sativum L.) with a broad range of biological activities. Allicin is produced upon tissue damage from the non-proteinogenic amino acid alliin (S-allylcysteine sulfoxide) in a ...
Jan Borlinghaus +2 more
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International Journal of Medical Microbiology, 2020 Allicin (diallylthiosulfinate) is a potent antimicrobial substance, produced by garlic tissues upon wounding as a defence against pathogens and pests.
Lars Ingo Ole Leichert
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Computational study of the therapeutic properties of allicin and its nanocomplexes using DFT and molecular docking techniques [PDF]
Scientific ReportsThis study investigated the anti-inflammatory, anticancer, antiviral, and antibacterial effects of allicin and its complexes (Allicin/C₂₄, Allicin/B₁₂N₁₂, and Allicin/Al₁₂N₁₂) using advanced computational techniques such as Density Functional Theory (DFT)
E. S. Mozafari +2 more
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Allicin-loaded hydrogel enhances the viability of multiterritory perforator flap [PDF]
Materials Today BioThe multiterritory perforator flap has gained increasing clinical adoption in limb reconstruction and wound repair due to its procedural simplicity and distinct clinical advantages.
Xuankuai Chen +11 more
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Evaluate the stability of synthesized allicin and its reactivity with endogenous compounds in garlic [PDF]
npj Science of FoodThe study aimed to prepare allicin in large quantities and evaluate the effects of different conditions and endogenous substances (polyphenols and free amino acids) in garlic on its stability. The optimized synthesis conditions of allicin (DADS:HAc = 2:9,
Shanshan Zhou +7 more
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Allicin ameliorates acute myocardial infarction in rats by modulating calcium homeostasis in cardiomyocytes through the induction of hydrogen sulfide production [PDF]
Frontiers in PharmacologyBackgroundAcute myocardial infarction (AMI) is a common cardiovascular disease with high morbidity and mortality rates. Allicin, the primary active component of traditional Chinese herbs garlic, has multiple cardiovascular effects.
Weiyu Liu +10 more
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Molecules, 2017 Garlic (Allium sativum) has potent antimicrobial activity due to allicin (diallylthiosulfinate) synthesized by enzyme catalysis in damaged garlic tissues. Allicin gives crushed garlic its characteristic odor and its volatility makes it potentially useful
Mark van der Linden +2 more
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Allicin enhances urea-N conversion to microbial-N by inhibiting urease activity and modulating the rumen microbiome in cattle [PDF]
MicrobiomeBackground Urea serves as a vital nonprotein nitrogen source in ruminant nutrition, but its efficient utilization is often hampered due to rapid urease activity in the rumen.
Shiqi Zhang +3 more
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Allicin induced AMPK signaling attenuated Smad3 pathway mediated lung fibrosis [PDF]
Scientific ReportsAllicin, a natural compound derived from garlic, protects against oxidative stress-mediated tissue inflammation and vascular remodeling. Although these are key processes in lung fibrosis, the effects of allicin on this disease have never been evaluated ...
Shun Nakazawa +15 more
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