MoleculesNatural products, particularly medicinal plants, are crucial in combating cancer and aiding in the discovery and development of new therapeutic agents owing to their biologically active compounds.
Wamidh H. Talib +7 more
semanticscholar +4 more sources
Thermal degradation, antioxidant and antimicrobial activity of the synthesized allicin and allicin incorporated in gel [PDF]
Hemijska Industrija, 2010 The main carriers of the pharmacological activity of garlic (Allium sativum L.) are organic sulfur compounds, the most important among them being allicin, a sulfenic acid thioester, or allylthiosulfonate.
Ilić Dušica P. +4 more
doaj +2 more sources
S-thioallylation of proteins by the garlic defence substance allicin and its biological effects [PDF]
Free Radical Biology and Medicine, 2019 A single clove of edible garlic (Allium sativum L.) of about 10 g produces up to 5 mg of allicin (diallylthiosulfinate), a thiol-reactive sulfur-containing defence substance that gives injured garlic tissue its characteristic smell.
Antelmann, Haike +5 more
core +4 more sources
Allicin, the Odor of Freshly Crushed Garlic: A Review of Recent Progress in Understanding Allicin’s Effects on Cells [PDF]
Molecules, 2021 The volatile organic sulfur compound allicin (diallyl thiosulfinate) is produced as a defense substance when garlic (Allium sativum) tissues are damaged, for example by the activities of pathogens or pests. Allicin gives crushed garlic its characteristic
Jan Borlinghaus +6 more
semanticscholar +5 more sources
Allicin disrupts cardiac Cav1.2 channels via trafficking [PDF]
Pharmaceutical Biology, 2019 Context: Allicin is a potential antiarrhythmic agent. The antiarrhythmic properties of allicin rely on its blockade of various cardiac ion channels.
Dan Han +5 more
doaj +3 more sources
Allicin Regulates Energy Homeostasis through Brown Adipose Tissue [PDF]
iScience, 2020 Summary: Brown adipose tissue (BAT) is a promising potential therapeutic target for the treatment of obesity and related metabolic diseases. Allicin, a natural product in garlic, has multiple biological and pharmacological functions. However, the role of
Chuanhai Zhang +13 more
doaj +3 more sources
Antifungal Activity and Potential Action Mechanism of Allicin against Trichosporon asahii
Microbiology Spectrum, 2023 Trichosporon asahii is an emerging opportunistic pathogen that causes potentially fatal disseminated trichosporonosis. The global prevalence of coronavirus disease 2019 (COVID-19) poses an increasing fungal infection burden caused by T. asahii.
Xin Yang +9 more
doaj +2 more sources
Allicin, an Antioxidant and Neuroprotective Agent, Ameliorates Cognitive Impairment
Antioxidants, 2021 Allicin (diallylthiosulfinate) is a defense molecule produced by cellular contents of garlic (Allium sativum L.). On tissue damage, the non-proteinogenic amino acid alliin (S-allylcysteine sulfoxide) is converted to allicin in an enzyme-mediated process ...
Muhammad Shahid Nadeem +4 more
doaj +2 more sources
Shelf-Life Extension of Chicken Fillets Using Flaxseed Mucilage Coatings Incorporated With Bixin-Allicin or Bixin-Orange Peel Essential Oil Nanoemulsions. [PDF]
Food Sci NutrFlaxseed mucilage incorporated with bixin‐allicin or bixin‐orange peel oil nanoemulsions significantly extended the shelf‐life and quality of fresh chicken fillets. ABSTRACT This study evaluated the properties of orange peel essential oil (OPE) and allicin emulsions and their efficacy in flaxseed mucilage‐bixin (FM‐B) coating for preserving chicken ...
Hashemi N, Milani E, Koocheki A.
europepmc +2 more sources
Heliyon, 2022 The antitumor effects of allicin have been demonstrated in various cancers. However, whether allicin improves esophageal squamous cell carcinoma (ESCC) has not yet been explored. The present study aimed to explore the function and underlying mechanism of
Zhanfang Guo, Yanjiao Zhang
doaj +1 more source