Results 91 to 100 of about 4,990 (168)

Post-transfusion purpura in an African-American man due to human platelet antigen-5b alloantibody: a case report [PDF]

, 2012
Introduction Post-transfusion purpura is a rare immunohematological disorder characterized by severe thrombocytopenia following transfusion of blood components and induced by an alloantibody against a donor platelet antigen.
Alcorn Kirsten, Filipa Lynce, Yin Fang, Lynce Filipa, Yin, Fang, Malkovska, Vera, Fang Yin, Lynce, F, Yin, F, Alcorn, K, Malkovska, V, Alcorn, Kirsten, Malkovska Vera, Lynce, Filipa, Vera Malkovska, Kirsten Alcorn   +15 more
core   +2 more sources

Red cell alloimmunization among haemato-oncologic patients in a teaching hospital in Malaysia

Sri Lanka Journal of Medicine, 2019
Background: The aim of the study is to estimate the prevalence and specificity of red blood cell alloantibody among haemato-oncologic patients and to correlate the association of antibody development with other factors such as age, gender, race, number ...
Noor Haslina Mohd Noor, norahninzu arifin, mohd nazri hassan, rapiaah mustaffa   +3 more
doaj   +1 more source

Delayed Cytotoxic T Lymphocyte–Associated Protein 4–Immunoglobulin Treatment Reverses Ongoing Alloantibody Responses and Rescues Allografts From Acute Rejection [PDF]

, 2016
Antibody-mediated rejection has emerged as the leading cause of late graft loss in kidney transplant recipients, and inhibition of donor-specific antibody production should lead to improved transplant outcomes.
Miller, ML, Vu, V, Chen, J, Chong, AS, Sciammas, R, Alegre, M-L, Tian, C, Young, JS, Moon, JJ   +8 more
core   +1 more source

Characterization of hemolytic transfusion reactions induced by anti-E antibodies

Zhongguo shuxue zazhi
[Objective] To investigate the causes and characteristics of immune hemolytic transfusion reactions (HTRs) triggered by anti-E antibodies, so as to provide a scientific reference for guaranteeing clinical blood transfusion safety. [Methods] Five patients
HUANG Huali, LI Hao, WEI Yuerong, LUO Ruixian, HUANG Huini, XIE Huiqiong, LI Hailan, YANG Ziji, MO Zhuning   +8 more
doaj   +1 more source

Higher prevalence of anti-S and anti-M in South India: A single-center cross-sectional analytical study

Asian Journal of Transfusion Science
INTRODUCTION: Alloimmunization, a dreadful complication of blood transfusion, varies between populations and geographical regions. The antibody prevalence of the South Indian population was studied as the data were scarce.
P. Sriraman, Dibyajyoti Sahoo, Abhishekh Basavarajegowda, Esha Toora   +3 more
doaj   +1 more source

Transfusion management in two patients with anti-f antibodies – A case report and review of the literature

Asian Journal of Transfusion Science
The anti-f antibody is rarely encountered in the immunohematology laboratory. It is against the compound antigen “ce” or “f.” The “f-“antigen is only expressed when both c and e alleles are present in the cis position on the same haplotype.
Debapriya Basu, Durba Biswas, Ayesha Sinha, Najla Haneefa Basheela, Ritam Chakrabarty, Suvro Sankha Datta   +5 more
doaj   +1 more source

Red blood cell alloantibodies in patients with thalassemia major referred to the blood transfusion center of Golestan province, Iran [PDF]

Medical Laboratory Journal
Background: One of the major complications in thalassemia patients is alloimmunization, which occurs when the patient produces antibodies against transfused Red Blood Cells (RBCs). In the present study, the frequency of alloantibodies was investigated in
Seyed Sadegh Baniaghil, Fardin Balochi, Ereste Kazzak   +2 more
doaj  

Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01

, 2019
Our understanding of the conformational and electrostatic determinants that underlie targeting of human leukocyte antigens (HLA) by anti-HLA alloantibodies is principally based upon in silico modelling.
Gascoigne, Nicholas R. J., Purushotorman, Kiren, Lescar, Julien, Yap, Jiawei, Vathsala, Anantharaman, Wong, Yee Hwa, El Sahili, Abbas, Chan, Conrad E. Z., Teo, Rachel Z. C., Hanson, Brendon J., Goh, Angeline T. H., MacAry, Paul A., Gu, Yue, Liew, Chong Wai, Wood, Kathryn J., Hamidinia, Maryam, Murali, Tanusya M., Too, Chien Tei   +17 more
core   +1 more source

Clinical Significance Of An Alloantibody Against The Kell Blood Group Glycoprotein

, 2017
Kell null (K-0) individuals can produce anti-Ku, an antibody against many epitopes in the Kell glycoprotein, after transfusion and/or pregnancy. Since sensitized K-0 patients are rare, little is known about anti-Ku clinical relevance and in particular ...
Nestor; Silvia Biondi, Claudia; Castilho, Claudia; Trucco Boggione, Carolina; Lujan Brajovich, Melina Eliana; Trejo, Andrea; Zani, Carine; Cespedes, Stella; Arnoni, Rosario; Nonaka, Lilian; Miguel Cotorruelo, Maris Mattaloni, Carlos   +11 more
core   +1 more source

Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans

, 2012
Chronic GVHD (cGVHD) poses a significant risk for HSCT patients. Preclinical development of new therapeutic modalities has been hindered by models with pathologic findings that may not simulate the development of human cGVHD.
Ryan Flynn, Jeffrey L. Browning, Bruce R. Blazar, William J. Murphy, Andrew Price, Patricia A. Taylor, Joseph H. Antin, Jerome Ritz, Angela Panoskaltsis-Mortari, Leo Luznik, Ann Ranger, Mark J. Shlomchik, Mathangi Srinivasan   +12 more
core   +1 more source