Stable dose cannabinoid medicine (Sativex®, THC+CBD) can provide sustained efficacy in the treatment of refractory painful diabetic neuropathy or other peripheral neuropathic pain associated with allodynia [poster] [PDF]
, 2008 No abstract ...
Hoggart, B. +3 more
core
Current and Future Issues in the Development of Spinal Agents for the Management of Pain. [PDF]
, 2017 Targeting analgesic drugs for spinal delivery reflects the fact that while the conscious experience of pain is mediated supraspinally, input initiated by high intensity stimuli, tissue injury and/or nerve injury is encoded at the level of the spinal ...
Fisher, Casey J +3 more
core +2 more sources
Burning Mouth Syndrome Underlying Factors: A Roadmap From a Network Perspective
Oral Diseases, EarlyView.ABSTRACT Objective To investigate the relationship between biological, psychological, and social factors underlying Burning Mouth Syndrome (BMS). Subjects and Methods A case (n = 40) and control (n = 42) study containing 80 variables was examined using two network models based on regularized partial correlations (n = 82).
Oscar Gabriel Castaño‐Joaqui +3 more
wiley +1 more source
Co-Localization of p-CREB and p-NR1 in Spinothalamic Neurons in a Chronic Muscle Pain Model [PDF]
, 2007 Activation of the cAMP pathway is an important mediator of chronic muscle pain. This study examined phosphorylation of the transcription factor cAMP-response-element-binding protein (p-CREB) and the NR1 subunit of the NMDA receptor (p-NR1) in the spinal ...
Bement, Marie K. Hoeger +1 more
core +2 more sources
Journal of Pain Research, 2018 Liandong Li,1 Yawei Han,2 Tengshuai Li,1 Jiaming Zhou,1 Chao Sun,3,4 Yuan Xue1 1Department of Orthopaedics Surgery, Tianjin Medical University General Hospital, Tianjin, China; 2Department of Histology and Embryology, School of Basic Medical Sciences ...
Li L, Han Y, Li T, Zhou J, Sun C, Xue Y
doaj
The Sympathetic Nervous System Contributes to Capsaicin-Evoked Mechanical Allodynia But Not Pinprick Hyperalgesia in Humans [PDF]
, 1996 Maywin Liu +4 more
openalex +1 more source
Serum Biomarkers and Their Clinical Correlates in Traumatic Trigeminal Neuropathy: A Pilot Study
Oral Diseases, EarlyView.ABSTRACT Objectives This study aims to investigate the serum biomarker levels in patients with painful post‐traumatic trigeminal neuropathy (PPTTN) and explore the associations between these biomarkers and the clinical and psychological characteristics of the patients. Materials and Methods A total of 32 patients with PPTTN were included.
Hye‐Kyoung Kim +2 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Transient receptor potential ankyrin 1 (TRPA1) and melastatin 3 (TRPM3) activation regulate pre‐ and postsynaptic Ca2+ concentrations and synaptic activity in the dorsal horn of the spinal cord. Left: a model that describes how activation of TRPA1 and TRPM3 channels induces an influx of Ca2+ in the central terminals of sensory ...
Yaroslav E. Andrianov +10 more
wiley +1 more source
Current status and future directions of botulinum neurotoxins for targeting pain processing. [PDF]
, 2015 Current evidence suggests that botulinum neurotoxins (BoNTs) A1 and B1, given locally into peripheral tissues such as skin, muscles, and joints, alter nociceptive processing otherwise initiated by inflammation or nerve injury in animal models and humans.
Pellett, Sabine +2 more
core +2 more sources
Allodynia in cluster headache: a review
Headache Medicine, 2011 Allodynia is defined as the experience of pain due to nonpainful stimuli, and occurs in several clinical contexts, including primary headaches. Cluster headache is a primary cephalalgia which is more common in males, characterized by excruciating pain, and autonomic trigeminal dysfunction.
Marcelo Moraes Valença +2 more
openaire +2 more sources