Results 111 to 120 of about 32,744 (263)

Trigeminal‐mediated headshaking in horses

Equine Veterinary Education, Volume 37, Issue 12, Page 619-621, December 2025.
Summary This clinical commentary is accompanying the manuscript on quantitative sensory testing and trigemino‐cervical thresholds in a Warmblood gelding affected by trigeminal‐mediated headshaking by Käfer‐Karrer et al. This new diagnostic method is promising for diagnosing a devastating disease which has an enormous impact on the horses welfare.
A. May, V. Franzen
wiley   +1 more source

A peroxynitrite decomposition catalyst prevents mechanical allodynia and NMDA receptor activation in the hind-paw ischemia reperfusion injury rats

, 2013
Kyung Hwa Kwak, Hoon Jung, Jun Mo Park, Jinseok Yeo, Hyunjee Kim, Hyung‐Chul Lee, Sung Hye Byun, Jong-Chan Kim, Sung-Sik Park, Dong Gun Lim   +9 more
openalex   +2 more sources

Oral KDS2010, a Monoamine Oxidase‐B (MAO‐B) Inhibitor, Slows the Deterioration of Motor Coordination in Genetic SCA1 Models by Inhibiting Astrocytic MAO‐B‐Mediated Inflammation

Journal of Neurochemistry, Volume 169, Issue 12, December 2025.
Astrocytes play a critical role in neurodegenerative disease pathology by modulating inflammatory responses and clearing toxic protein aggregates. In this study, we evaluated the therapeutic potential of KDS2010, a reversible and selective MAO‐B inhibitor, in a mouse model of spinocerebellar ataxia type 1 (SCA1).
Dong Ho Woo, Ju‐Hyun Jeon, Hye‐Jin Ryu, Gyeong Min Lee, Hye‐Won Lim, Ki Duk Park, Kwang Lae Hoe, Sang Dal Rhee   +7 more
wiley   +1 more source

Characterization of nociceptin-induced allodynia and hyperalgesia

, 1998
Toshiaki Minami, Emiko Okuda‐Ashitaka, Hidemaro Mori, Kenji Sakimura, Masayoshi Mishina, Seiji Ito   +5 more
openalex   +1 more source

Peripherally administered cannabinoid receptor 2 (CB2R) agonists lose anti-allodynic effects in TRPV1 knockout mice, while intrathecal administration leads to anti-allodynia and reduced GFAP, CCL2 and TRPV1 expression in the dorsal spinal cord and DRG [PDF]

, 2021
Jenny L. Wilkerson, Lauren B. Alberti, Ganesh A. Thakur, Alexandros Makriyannis, Erin D. Milligan   +4 more
openalex   +1 more source

Dopamine and prolactin in migraine: Mechanisms and potential therapeutic targets

Journal of Neuroendocrinology, Volume 37, Issue 12, December 2025.
Prolactin and dopamine modulate migraine‐relevant trigeminal pathways. Hyperprolactinemia is associated with migraine‐like headache, and preclinical studies show that prolactin enhances trigeminal excitability, particularly in females. Dopamine inhibits prolactin release and may also directly suppress trigeminovascular activity via D2 receptors in the ...
Astrid Johannesson Hjelholt, Randi Maria Hanghøj Tei, Hans Christoph Diener, Jens Otto Lunde Jørgensen   +3 more
wiley   +1 more source

Molecular Characterization of Oxaliplatin‐Induced Peripheral Neurotoxicity: The Complex Spectrum of Painful Manifestations

Journal of the Peripheral Nervous System, Volume 30, Issue 4, December 2025.
ABSTRACT Background and Aims Oxaliplatin (OHP) induced peripheral neurotoxicity (OIPN) is a complex spectrum comprising an acute and a chronic form. Acute OIPN leads to unpleasant transient sensations in the 24–72 h after chemotherapy, due to a temporary dysfunction in ion channels (i.e., axonal hyperexcitability in the absence of anatomical damage ...
Eleonora Pozzi, Maria Pina Serra, Marianna Boi, Annalisa Canta, Alessia Chiorazzi, Chiara Capelli, Chiara Invernizzi, Elisa Ballarini, Virginia Rodriguez‐Menendez, Margherita Francesca Kraus, Marina Quartu, Guido Cavaletti, Paola Alberti   +12 more
wiley   +1 more source

Antiallodynic and antihyperalgesic activities of zerumbone via the suppression of IL-1β, IL-6, and TNF-α in a mouse model of neuropathic pain

Journal of Pain Research, 2017
Banulata Gopalsamy, Ahmad Akira Omar Farouk, Tengku Azam Shah Tengku Mohamad, Mohd Roslan Sulaiman, Enoch Kumar Perimal Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang ...
Gopalsamy B, Farouk AAO, Tengku Mohamad TAS, Sulaiman MR, Perimal EK   +4 more
doaj  

Blood 1‐Deoxysphingolipid Levels Are Associated With Epidermal Denervation in Small Fiber Neuropathy

Journal of the Peripheral Nervous System, Volume 30, Issue 4, December 2025.
ABSTRACT Background and Aims Dysfunctional sphingolipid metabolism leads to nerve fiber degeneration, particularly of small caliber Aδ and C fibers, in hereditary sensory and autonomic neuropathies. We aimed to investigate the association of blood 1‐deoxysphingolipid (1‐deoxySL) profiles and skin denervation in idiopathic small fiber neuropathy (SFN ...
Luisa Kreß, Caren Meyer zu Altenschildesche, Nadine Egenolf, Claudia Sommer, Thorsten Hornemann, Nurcan Üçeyler   +5 more
wiley   +1 more source

Targeting the endogenous cannabinoid system to treat chronic neuropathic pain

Frontiers in Pharmacology, 2014
Benjamin K Lau, Christopher W Vaughan
doaj   +1 more source