Results 111 to 120 of about 66,158 (349)
BiomedicinesThe use of paclitaxel as a chemotherapeutic drug is limited by the development of dose-dependent paclitaxel-induced neuropathic pain (PINP). Recently, we observed that the combination of indomethacin plus minocycline (IPM) attenuates PINP in a mouse ...
Willias Masocha +3 more
doaj +1 more source
Scientific Reports, 2022 Whisker pad skin incision in infancy causes the prolongation of mechanical allodynia after re-incision in adulthood. A recent study also proposed the importance of sex differences in pain signaling in the spinal cord.
Jo Otsuji +8 more
doaj +1 more source
International Journal of Molecular Medicine, 2018 Primary damage or dysfunction of the nervous system may cause or initiate neuropathic pain. However, it has been difficult to establish an effective treatment for neuropathic pain, as the mechanisms responsible for its pathology remain largely unknown ...
Hongguang Chen +8 more
semanticscholar +1 more source
Role of Gynecologic Findings in Interstitial Cystitis/Bladder Pain Syndrome: A Consensus
Neurourology and Urodynamics, EarlyView.ABSTRACT Objective To evaluate the role of gynecologic findings in Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) by reviewing current international guidelines and identifying relevant gynecologic co‐morbidities. Methods This consensus statement was developed through a systematic four‐phase process: (1) comprehensive literature review across ...
Marie E. Sullivan +5 more
wiley +1 more source
Journal of Pain Research, 2016 RP Lazaro Department of Neurology, Albany Medical College, Albany, NY, USA Objective: The aim of this study was to demonstrate the ramifications of clinical variability of complex regional pain syndrome (CRPS) and how they can affect the various aspects ...
Lazaro RP
doaj
Acute- and late-phase matrix metalloproteinase (MMP)-9 activity is comparable in female and male rats after peripheral nerve injury. [PDF]
, 2018 BACKGROUND:In the peripheral nerve, pro-inflammatory matrix metalloproteinase (MMP)-9 performs essential functions in the acute response to injury. Whether MMP-9 activity contributes to late-phase injury or whether MMP-9 expression or activity after ...
Angert, Mila +6 more
core +2 more sources
Journal of Neuroscience, 2018 Mechanical allodynia, a widespread pain symptom that still lacks effective therapy, is associated with the activation of a dorsally directed polysynaptic circuit within the spinal dorsal horn (SDH) or medullary dorsal horn (MDH), whereby tactile inputs ...
Cristina Alba-Delgado +6 more
semanticscholar +1 more source
physica status solidi (RRL) – Rapid Research Letters, EarlyView.For the advancement of neuromorphic computing and bio‐integrated electronics, a dual‐stacked ITO/IGZO/ZrO2/Ti resistive random access memory (RRAM) device with oxygen vacancy engineering is demonstrated for reliable synaptic and nociceptive behavior. Gradual potentiation and depression, along with biologically inspired spike‐timing‐dependent plasticity
Seo‐Young Jo +4 more
wiley +1 more source
Veterinary Record Case Reports, EarlyView.Abstract A 6‐year‐old, male, entire Jack Russell terrier was referred for noise fear and subsequently diagnosed with underlying musculoskeletal discomfort. Significant improvements in the signs were reported by the clients by initially addressing the underlying discomfort using a combination of analgesia (1.7 mg/kg carprofen once a day), environmental ...
Beverley M. Wilson, Daniel S. Mills
wiley +1 more source
Tissue-type plasminogen activator-primed human iPSC-derived neural progenitor cells promote motor recovery after severe spinal cord injury. [PDF]
, 2019 The goal of stem cell therapy for spinal cord injury (SCI) is to restore motor function without exacerbating pain. Induced pluripotent stem cells (iPSC) may be administered by autologous transplantation, avoiding immunologic challenges.
Brifault, Coralie +11 more
core