Results 11 to 20 of about 66,158 (349)

Cutaneous allodynia in the migraine population [PDF]

Annals of Neurology, 2007
AbstractObjectiveTo develop and validate a questionnaire for assessing cutaneous allodynia (CA), and to estimate the prevalence and severity of CA in the migraine population.MethodsMigraineurs (n = 11,388) completed the Allodynia Symptom Checklist, assessing the frequency of allodynia symptoms during headache. Response options were never (0), rarely (0)
Richard B. Lipton, Marcelo E. Bigal, Sait Ashina, Rami Burstein, Stephen D. Silberstein, Michael L. Reed, Daniel Serrano, Walter F. Stewart   +7 more
openalex   +4 more sources

Mechanical allodynia [PDF]

Pflügers Archiv - European Journal of Physiology, 2014
Mechanical allodynia (other pain) is a painful sensation caused by innocuous stimuli like light touch. Unlike inflammatory hyperalgesia that has a protective role, allodynia has no obvious biological utility. Allodynia is associated with nerve damage in conditions such as diabetes, and is likely to become an increasing clinical problem.
Lolignier, Stéphane, Eijkelkamp, Niels, Wood, John   +2 more
openaire   +6 more sources

Ictal and interictal brain activation in episodic migraine: Neural basis for extent of allodynia.

PLoS ONE, 2021
In some patients, migraine attacks are associated with symptoms of allodynia which can be localized (cephalic) or generalized (extracephalic). Using functional neuroimaging and cutaneous thermal stimulation, we aimed to investigate the differences in ...
Nasim Maleki, E. Szabó, L. Becerra, E. Moulton, S. Scrivani, R. Burstein, D. Borsook   +6 more
semanticscholar   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

The interaction of intrathecal neostigmine and N-cyclohexyladenosine on anti-allodynic effects in rats with a nerve ligation injury [PDF]

Korean Journal of Anesthesiology, 2010
BackgroundNerve ligation injury in rats produces a pain syndrome that includes mechanical allodynia. Intrathecal administration of cholinesterase inhibitors or adenosine receptor agonists have anti-allodynic effects in this model.
Dae Kee Choi, Seong Soo Choi, Jai Hyun Hwang   +2 more
doaj   +1 more source

Ultrasound-Guided combined greater occipital nerve block at the C2 level with trapezius trigger point injection and supraorbital-Supratrochlear nerve block: More effective on allodynia and disability in chronic migraine

Annals of Indian Academy of Neurology, 2023
Background: Chronic migraine (CM) patients with cutaneous allodynia (CA) show a poor response to treatment. Long-term studies have yet to be conducted to demonstrate the efficacy of blocks on CA.
Suna Aşkın Turan, şenay Aydın, Melih G Gözükara, Murat Çabalar   +3 more
doaj   +1 more source

BDNF promotes activation of astrocytes and microglia contributing to neuroinflammation and mechanical allodynia in cyclophosphamide-induced cystitis

Journal of Neuroinflammation, 2020
Patients with interstitial cystitis/bladder pain syndrome (IC/BPS) often grieve over a low quality of life brought about by chronic pain. In our previous studies, we determined that neuroinflammation of the spinal dorsal horn (SDH) was associated with ...
Honglu Ding, Jialiang Chen, Minzhi Su, Zhijun Lin, H. Zhan, Fei Yang, Wen-biao Li, Juncong Xie, Yong Huang, Xian-Guo Liu, Bolong Liu, Xiangfu Zhou   +11 more
semanticscholar   +1 more source

Frequent mild head injury promotes trigeminal sensitivity concomitant with microglial proliferation, astrocytosis, and increased neuropeptide levels in the trigeminal pain system. [PDF]

, 2017
BACKGROUND: Frequent mild head injuries or concussion along with the presence of headache may contribute to the persistence of concussion symptoms. METHODS: In this study, the acute effects of recovery between mild head injuries and the frequency of ...
Assari, Soroush, Cheng, Lan, Darvish, Kurosh, Elliott, Melanie B, Tyburski, Ashley L.   +4 more
core   +2 more sources

Recent advances in our understanding of the organization of dorsal horn neuron populations and their contribution to cutaneous mechanical allodynia

Journal of neural transmission, 2020
The dorsal horns of the spinal cord and the trigeminal nuclei in the brainstem contain neuron populations that are critical to process sensory information.
Cedric Peirs, R. Dallel, A. Todd
semanticscholar   +1 more source

Favorable outcome of early treatment of new onset child and adolescent migraine-implications for disease modification. [PDF]

, 2009
There is evidence that the prevalence of migraine in children and adolescents may be increasing. Current theories of migraine pathophysiology in adults suggest activation of central cortical and brainstem pathways in conjunction with the peripheral ...
A Ferrari, A Fox, A Hershey, A Hershey, AI Scher, AI Scher, Alan M. Rapoport, B Bille, B. L. Peterlin, C Waeber, C Wober, D D’Amico, D Loder, D Marcus, DC Haas, Fred D. Sheftell, G Fuller, HF Boardman, I Abu-Arefeh, JA Charles, JA Charles, James A. Charles, JF Fries, JL Brandes, K Ahoen, KMA Welch, L Pageler, L Peterlin, M Fanicullace, MA Kabbouche, Marielle A. Kabbouche, MC Kruit, ME Bigal, NH Raskin, NT Mathew, NT Mathew, P Winner, R Burstein, R Burstein, R Hering-Hanit, R Lipton, R Monastero, R Petrella, S Solomon, SD Silberstein, SD Silberstein, SL Linder, SL Linder, SL Linder, Steven L. Linder, W Split, WF Stewart, WF Stewart   +52 more
core   +1 more source