Results 21 to 30 of about 66,158 (349)

Vitamin D, Chronic Migraine, and Extracranial Pain: Is There a Link? Data From an Observational Study

Frontiers in Neurology, 2021
Several studies focused on the role of vitamin D (vitD) in pain chronification. This study focused on vitD level and pain chronification and extension in headache disorders.
Valentina Rebecchi, Daniela Gallo, Daniela Gallo, Lucia Princiotta Cariddi, Lucia Princiotta Cariddi, Eliana Piantanida, Eliana Piantanida, Payam Tabaee Damavandi, Payam Tabaee Damavandi, Federico Carimati, Marco Gallazzi, Alessandro Clemenzi, Paola Banfi, Elisa Candeloro, Maria Laura Tanda, Maria Laura Tanda, Marco Mauri, Marco Mauri, Maurizio Versino, Maurizio Versino   +19 more
doaj   +1 more source

Nociceptive neuropeptide increases and periorbital allodynia in a model of traumatic brain injury. [PDF]

, 2012
OBJECTIVE: This study tests the hypothesis that injury to the somatosensory cortex is associated with periorbital allodynia and increases in nociceptive neuropeptides in the brainstem in a mouse model of controlled cortical impact (CCI) injury.
Amenta, Peter S., Awe, Olatilewa, Elliott, Melanie B., Jallo, Jack I., Oshinsky, Michael L.   +4 more
core   +2 more sources

Nrf2 activation ameliorates mechanical allodynia in paclitaxel-induced neuropathic pain

Acta Pharmacologica Sinica, 2020
Paclitaxel-induced neuropathic pain (PINP) is refractory to currently used analgesics. Previous studies show a pivotal role of oxidative stress in PINP.
Ya-Qun Zhou, Dai-Qiang Liu, Shu-ping Chen, Nan Chen, Jia Sun, Xiao-mei Wang, Fei Cao, Yu‐ke Tian, D. Ye   +8 more
semanticscholar   +1 more source

Induction of chronic migraine phenotypes in a rat model after environmental irritant exposure [PDF]

, 2017
Air pollution is linked to increased emergency department visits for headache and migraine patients frequently cite chemicals or odors as headache triggers, but the association between air pollutants and headache is not well understood.
Hurley, Joyce Harts, Johnson, Philip Lee, Kunkler, Phillip Edward, Oxford, Gerry Stephen, Zhang, LuJuan   +4 more
core   +1 more source

Electroacupuncture Ameliorates Mechanical Allodynia of a Rat Model of CRPS-I via Suppressing NLRP3 Inflammasome Activation in Spinal Cord Dorsal Horn Neurons

Frontiers in Cellular Neuroscience, 2022
Complex regional pain syndrome type-I (CRPS-I) is a chronic neurological disorder that results in severe pain and affects patients' life quality. Conventional therapies usually lack effectiveness.
Yunwen Zhang, Ruixiang Chen, Ruixiang Chen, Qimiao Hu, Jie Wang, Huimin Nie, Chengyu Yin, Yuanyuan Li, Huina Wei, Boyu Liu, Yan Tai, Junfan Fang, Xiaomei Shao, Xiaoqing Jin, Jianqiao Fang, Boyi Liu   +15 more
doaj   +1 more source

Multicenter assessment of quantitative sensory testing (QST) for the detection of neuropathic-like pain responses using the topical capsaicin model [PDF]

, 2018
Background: The use of quantitative sensory testing (QST) in multicenter studies has been quite limited, due in part to lack of standardized procedures among centers. Aim: The aim of this study was to assess the application of the capsaicin pain model
Bushnell, M. Catherine, Chouchou, Florian, Ferland, Catherine E., Gandhi, Wiebke, Jackson, Philip L., Lavigne, Gilles, Ma, My-Linh, Marchand, Serge, Michon, Pierre-Emmanuel, Parent, Alexandre J., Rainville, Pierre, Schweinhardt, Petra, Villemure, Chantal, Ware, Mark A.   +13 more
core   +1 more source

Resveratrol mediates mechanical allodynia through modulating inflammatory response via the TREM2-autophagy axis in SNI rat model

Journal of Neuroinflammation, 2020
Background Neuropathic pain (NeuP) is a chronic and challenging clinical problem, with little effective treatment. Resveratrol has shown neuroprotection by inhibiting inflammatory response in NeuP.
Yaping Wang, Yu Shi, Yong-quan Huang, Wei Liu, Guiyuan Cai, Shimin Huang, Yanyan Zeng, Siqiang Ren, Hongrui Zhan, Wen Wu   +9 more
semanticscholar   +1 more source

Temporal changes in the expression of the translocator protein TSPO and the steroidogenic enzyme 5a-reductase in the dorsal spinal cord of animals with neuropathic pain: effects of progesterone administration [PDF]

, 2016
Neuropathic pain is a frequent complication of spinal cord injury (SCI), still refractory to conventional treatment. The presence and biological activity of steroidogenic regulatory proteins and enzymes in the spinal cord suggests that neurosteroids ...
Adler, Natalia Sol, Coronel, Maria Florencia, de Nicola, Alejandro Federico, Gonzalez, Susana Laura, Labombarda, Maria Florencia, Raggio, María Celeste, Sánchez Granel, María Luz   +6 more
core   +2 more sources

Effects of Goshajinkigan, Hachimijiogan, and Rokumigan on Mechanical Allodynia Induced by Paclitaxel in Mice

Journal of Traditional and Complementary Medicine, 2014
Peripheral neuropathy is a major dose-limiting side effect of the chemotherapeutic agent paclitaxel. This study examined whether the three related traditional herbal formulations, goshajinkigan (GJG; 牛車腎氣丸 Niú Chē Shèn Qì Wán), hachimijiogan (HJG; 八味地黃丸 ...
Tsugunobu Andoh, Ryo Kitamura, Hirotoshi Fushimi, Katsuko Komatsu, Naotoshi Shibahara, Yasushi Kuraishi   +5 more
doaj   +1 more source

Peedanil Gold, Herbo-Mineral Formulation, Moderates Cytokine Levels and Attenuates Pathophysiology in Monosodium Iodoacetate Induced Osteoarthritis in SD Rat Model

Frontiers in Pharmacology, 2022
The inflammatory cartilaginous degeneration of the articular joints, mostly those of knee, hips and hands, is osteoarthritis (OA). The available treatment strategies for osteoarthritis are designed for pain relief, molecular targeting, cartilage ...
Acharya Balkrishna, Acharya Balkrishna, Sandeep Sinha, Shadrak Karumuri, Jyotish Srivastava, Swati Haldar, Anurag Varshney, Anurag Varshney, Anurag Varshney   +8 more
doaj   +1 more source