Results 81 to 90 of about 55,599 (275)

RNA Sequencing Dataset of Drosophila Nociceptor Translatomic Response to Injury

Data
To prepare to address the mechanisms of injury-induced nociceptor sensitization, we sequenced the translatome of the nociceptors of injured Drosophila larvae and those of uninjured larvae.
Christine M. Hale, Kyle J. Beauchemin, Courtney L. Brann, Julie K. Moulton, Ramaz Geguchadze, Benjamin J. Harrison, Geoffrey K. Ganter   +6 more
doaj   +1 more source

Activation of peripheral NOP receptors reduces periorbital mechanical allodynia evoked by CGRP in mice

British Journal of Pharmacology, EarlyView.
Background and Purpose Migraine is a neurovascular disorder largely mediated by calcitonin gene‐related peptide (CGRP). This study explores the role of the nociceptin/orphanin FQ (N/OFQ)–N/OFQ receptor (NOP) system in CGRP‐induced periorbital mechanical allodynia (PMA) in mice.
Chiara Sturaro, Pietro Pola, Michela Argentieri, Alessia Frezza, Matilde Marini, Francesco De Logu, Valentina Albanese, Marie Soukupova, Davide Malfacini, Nurulain T. Zaveri, Romina Nassini, Dane D. Jensen, Pierangelo Geppetti, Girolamo Calò, Chiara Ruzza   +14 more
wiley   +1 more source

Piezo2 in Mechanosensory Biology: From Physiological Homeostasis to Disease‐Promoting Mechanisms

Cell Proliferation, EarlyView.
Piezo2 channels are essential mechanotransducers regulating touch, proprioception and visceral mechanosensation across physiological systems, emerging as therapeutic targets for pathological mechanical hypersensitivity and neurogenic disorders. ABSTRACT Piezo2, a mechanically activated ion channel, serves as the key molecular transducer for touch ...
Zhebin Cheng, Zuping Wu, Mengjie Wu, Liang Xie, Qianming Chen   +4 more
wiley   +1 more source

Antiallodynic Effects of Bee Venom in an Animal Model of Complex Regional Pain Syndrome Type 1 (CRPS-I)

Toxins, 2017
Neuropathic pain in a chronic post-ischaemic pain (CPIP) model mimics the symptoms of complex regional pain syndrome type I (CRPS I). The administration of bee venom (BV) has been utilized in Eastern medicine to treat chronic inflammatory diseases ...
Sung Hyun Lee, Jae Min Lee, Yun Hong Kim, Jung Hyun Choi, Seung Hwan Jeon, Dong Kyu Kim, Hyeon Do Jeong, You Jung Lee, Hue Jung Park   +8 more
doaj   +1 more source

Trigeminal‐mediated headshaking in horses

Equine Veterinary Education, EarlyView.
Summary This clinical commentary is accompanying the manuscript on quantitative sensory testing and trigemino‐cervical thresholds in a Warmblood gelding affected by trigeminal‐mediated headshaking by Käfer‐Karrer et al. This new diagnostic method is promising for diagnosing a devastating disease which has an enormous impact on the horses welfare.
A. May, V. Franzen
wiley   +1 more source

The analgesic effect of intravenous methylprednisolone on acute neuropathic pain with allodynia due to central cord syndrome: a retrospective study

Journal of Pain Research, 2018
Liandong Li,1 Yawei Han,2 Tengshuai Li,1 Jiaming Zhou,1 Chao Sun,3,4 Yuan Xue1 1Department of Orthopaedics Surgery, Tianjin Medical University General Hospital, Tianjin, China; 2Department of Histology and Embryology, School of Basic Medical Sciences ...
Li L, Han Y, Li T, Zhou J, Sun C, Xue Y
doaj  

Lack of evidence for sprouting of Aβ afferents into the superficial laminas of the spinal cord dorsal horn after nerve section [PDF]

, 2003
The central arborizations of large myelinated cutaneous afferents normally extend as far dorsally as the ventral part of lamina II in rat spinal cord. Woolf et al. (1992) reported that after nerve injury some of these afferents sprouted into lamina I and
Hughes, D.I., Riddell, J.S., Scott, D.T., Todd, A.J.   +3 more
core   +1 more source

Subacute Painful Axonal Polyneuropathy Associated with Foslevodopa/Foscarbidopa Subcutaneous Infusion in Advanced Parkinson's Disease

Movement Disorders, EarlyView.
Aukusti Valli, Filip Scheperjans
wiley   +1 more source

The potential role of sleep quality in the relationship between glymphatic function and migraine frequency: Insights from a cross‐sectional study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study aimed to explore the association between glymphatic function, as assessed by the diffusion tensor imaging along perivascular space (DTI‐ALPS) index, and headache frequency in individuals with migraine. Additionally, it evaluated whether sleep quality modulates this relationship.
Raffaele Ornello, Federico Salfi, Maria Grazia Vittorini, Antonio Innocenzi, Federico De Santis, Federico Bruno, Francesca Pistoia, Michele Ferrara, Alessandra Splendiani, Simona Sacco   +9 more
wiley   +1 more source

Evaluating associations of migraine‐related vertigo

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective We set out to examine detailed phenotypic data from our clinic for associations of vertigo in chronic migraine. Background Vertigo is a non‐canonical, common symptom of migraine. Little is known about its associations with other symptoms within the migraine phenotype.
Nazia Karsan, Nicolas Vandenbussche, Robyn Jenia‐Wilcha, Pubudu Amarasena, Pannathat Soontrapa, Karthik Nagaraj, Carlo Lastarria Perez, Peter J. Goadsby   +7 more
wiley   +1 more source