Results 111 to 120 of about 307,259 (361)

Poor Outcome in a Mitochondrial Neurogastrointestinal Encephalomyopathy Patient with a Novel TYMP Mutation: The Need for Early Diagnosis. [PDF]

, 2012
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is a devastating autosomal recessive disorder due to mutations in TYMP, which cause loss of function of thymidine phosphorylase (TP), nucleoside accumulation in plasma and tissues and ...
Padovani Alessandro, SCARPELLI, Mauro, Anna Russignan, Padovani, A, PADOVANI, Alessandro, Bereczki, C, Paola Tonin, Bax Bridget E., Buono, R, Filosto Massimiliano, ZAPPINI, Francesca, Filosto M., Russignan, A, Bridget E. Bax, Alessandro Padovani, Zappini, F, Filosto, M, Bereczki Csaba, Bax, BE, Tonin, P, Massimiliano Filosto, Bax B. E., Padovani A., Zombor, M, Tonin Paola, Buono, Romina, Bereczki C., Zombor Melinda, Zombor M., Mauro Scarpelli, Romina Buono, Zappini Francesca, Scarpelli Mauro, Csaba Bereczki, Russignan Anna, Francesca Zappini, RUSSIGNAN, Anna, Buono Romina, TONIN, PAOLA, Melinda Zombor, Scarpelli, M   +40 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Allogeneic Stem Cell Transplantation Experience in Chronic Lymphocytic Leukemia

, 2018
Objective:Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. In pa-tients with poor prognosis, allogeneic stem cell transplantation (ASCT) treatment is an alterna-tive.
Osman İlhan, Günhan Gürman, Selami Koçak Toprak, Sinem Civriz Bozdağ, Muhit Özcan, Önder Arslan, Erden Atilla, Meltem Kurt Yüksel, Gültekin Pekcan, Pervin Topçuoğlu, Pınar Ataca Atilla   +10 more
core   +1 more source

Heme oxygenase-1: Equally important in allogeneic hematopoietic stem cell transplantation and organ transplantation?

, 2021
The intracellular enzyme heme oxygenase-1 (HO-1) is responsible for the degradation of cell-free (cf) heme. Cfheme, released upon cell damage and cell death from hemoglobin, mitochondria and myoglobin, functions as a powerful damage-associated molecular ...
Verheij, Myrddin, Zeerleder, Sacha, Voermans, Carlijn   +2 more
core   +1 more source

O transplante de células-tronco hematopoéticas como opção no tratamento de doenças não hematológicas Hematopoietic stem cell transplant: a therapeutic option for non-hematologic diseases

Revista Brasileira de Hematologia e Hemoterapia, 2009
Nesta revisão são abordadas as doenças em que existem dados e perspectivas do uso de transplante de células-tronco hematopoéticas em suas diversas modalidades.
Milton A. Ruiz, Lilian Piron-Ruiz, Mario R. Lago, Angelo Maset, Adriana B. Santos, Oswaldo T. Greco   +5 more
doaj   +1 more source

Immune Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation

Frontiers in Immunology, 2016
The timely reconstitution and regain of function of a donor-derived immune system is of utmost importance for the recovery and long-term survival of patients after allogeneic hematopoietic stem cell transplantation (HSCT).
J. Ogonek, Mateja Kralj Juric, Sakhila Ghimire, P. Varanasi, E. Holler, H. Greinix, E. Weissinger   +6 more
semanticscholar   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Corrigendum: Phase I trial outcome of amnion cell therapy in patients with ischemic stroke (I-ACT)

Frontiers in Neuroscience, 2023
Thanh G. Phan, Thanh G. Phan, Rebecca Lim, Rebecca Lim, Mirja Krause, Mirja Krause, Siow T. Chan, Siow T. Chan, Hannah McDonald, Hannah McDonald, Poh-Yi Gan, Poh-Yi Gan, Shenpeng R. Zhang, Liz J. Barreto Arce, Jason Vuong, Jason Vuong, Tharani Thirugnanachandran, Tharani Thirugnanachandran, Benjamin Clissold, Benjamin Clissold, John Ly, John Ly, Shaloo Singhal, Shaloo Singhal, Marie Veronic Hervet, Marie Veronic Hervet, Hyun Ah Kim, Grant R. Drummond, Euan M. Wallace, Euan M. Wallace, Henry Ma, Henry Ma, Christopher G. Sobey   +32 more
doaj   +1 more source

Immunoprivileged no more: measuring the immunogenicity of allogeneic adult mesenchymal stem cells

Stem cell research & therapeutics, 2017
BackgroundAutologous and allogeneic adult mesenchymal stem/stromal cells (MSCs) are increasingly being investigated for treating a wide range of clinical diseases. Allogeneic MSCs are especially attractive due to their potential to provide immediate care
A. Berglund, L. Fortier, D. Antczak, L. Schnabel   +3 more
semanticscholar   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source