Results 101 to 110 of about 193,019 (302)

Development of a sample bank and clinical database for the retrospective analysis of unrelated bone marrow transplants: a pilot study of 138 transplants using RSCA for high resolution HLA matching. [PDF]

, 2005
The Anthony Nolan Register provides donors for allogeneic stem cell transplantation for haematological disorders. A clinical database and sample bank were established for the ongoing analysis of transplants from Register donors.
Pay, A.L.P.
core  

Adoptive transfer of cytomegalovirus-specific CTL to stem cell transplant patients after selection by HLA–peptide tetramers [PDF]

, 2005
Stem cell transplantation is used widely in the management of a range of diseases of the hemopoietic system. Patients are immunosuppressed profoundly in the early posttransplant period, and reactivation of cytomegalovirus (CMV) remains a significant ...
Premini Mahendra, Craddock, Charles., McDonald, D, Billingham, Lucinda, Steward, Colin, Dorothy McDonald, Pourgheysari, Batoul, Eduardo Olavarria, Mahendra, Premini, Assenmacher, Mario., Olavarria, Eduardo, Tauro, Sudhir, Chakraverty, Ronjon., Goldman, John, Cobbold, Mark., Moss, Paul; id_orcid, Steward, Colin., McDonald, Dorothy, Pourgheysari Najafabadi, Batoul, John Goldman, Ronjon Chakraverty, Chakraverty, Ronjon, Crawley, Charles, Colin Steward, Billingham, Lucinda; id_orcid, Craddock, Charles; id_orcid, Assenmacher, Mario, Goldman, J, Pourgheysari, Batoul., Billingham, Lucinda., Tauro, S, Crawley, Charles., Charles Crawley, Osman, H, Batoul Pourgheysari, Naeem Khan, Mario Assenmacher, Osman, Husam, Assenmacher, M, Khan, Naeem, Goldman, John., Craddock, Charles, Mark Cobbold, Steward, C, McDonald, Dorothy., Olavarria, Eduardo., Olavarria, E, Husam Osman, Cobbold, Mark, Crawley, C, Osman, Husam., Mahendra, Premini., Sudhir Tauro, Tauro, Sudhir., Charles Craddock, Moss, Paul A. H., Moss, Paul A H, Khan, Naeem., Lucinda Billingham, Paul A.H. Moss, Moss, Paul A.H.   +60 more
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

allogeneic

Citation: 'allogeneic' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12862 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Cord blood mesenchymal stromal cells combined with hyaluronic acid show symptom-modifying and potential disease-modifying effects in an equine osteoarthritis fetlock chip model

Frontiers in Veterinary Science
IntroductionOsteoarthritis (OA) is a major cause of lameness in horses, and current therapies largely address clinical signs rather than disease progression.
Rodrigo M. Luque, Narman Mortagy, Terence C. McCorkell, Thomas G. Koch, Thomas G. Koch, Sahar Mehrpouyan, Amir Hamed Alizadeh, Keith A. Russell, Janet Beeler-Marfisi, Laurie R. Goodrich, Gabrielle Monteith, Alexander Valverde, Howard Dobson, Alex Zur Linden, Andres F. Giraldo, Judith B. Koenig   +15 more
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Multimodality, multidisciplinary approach to overcome technical challenges in a pediatric stem cell harvest for sickle cell disease with preformed donor-specific antibodies

Asian Journal of Transfusion Science
Sickle cell disease is a group of disorders caused by a mutation in the beta chain of hemoglobin (Hb) leading to a vicious cycle of HbS polymerization, increased adhesion-mediated vaso-occlusion and hemolysis-mediated endothelial dysfunction.
Mohit Chowdhry, S. Minu Lekshmi, Uday Kumar Thakur, Gaurav Kharya, Garima Nirmal   +4 more
doaj   +1 more source