Results 51 to 60 of about 6,115,227 (208)

Allogeneic Stem Cell Transplantation for Myelofibrosis in 2012 [PDF]

open access: yesBritish Journal of Haematology, 2012
Summary Myelofibrosis ( MF ) is a heterogeneous disease for which long‐term, effective medical therapeutic options are currently limited. The role of allogeneic haematopoietic stem cell transplant ( AHSCT ) in this population, many of ...
McLornan, Donal   +3 more
openaire   +5 more sources

Design and screening of novel endosomal escape compounds that enhance functional delivery of oligonucleotides in vitro

open access: yesMolecular Therapy: Nucleic Acids
Antisense oligonucleotides (ASOs), including splice-switching oligonucleotides (SSOs), are promising therapeutic approaches for targeting genetic defects.
H. Yesid Estupiñán   +12 more
doaj   +1 more source

Allogeneic stem cell transplantation in follicular lymphoma [PDF]

open access: yesBest Practice & Research Clinical Haematology, 2011
Myeloablative allogeneic transplantation in follicular lymphoma has been found to be particularly effective in patients with relapsed disease and an inadequate bone marrow reserve or massive bone marrow involvement. Allogeneic transplantation carries the promise of long-term disease control by graft-versus-lymphoma immunity but is associated with a 30%-
openaire   +2 more sources

Cerebral toxoplasmosis after haematopoietic stem cell transplantation [PDF]

open access: yes, 2017
Toxoplasmosis is an opportunistic infection caused by the parasite Toxoplasma gondii. The infection is severe and difficult to diagnose in patients receiving allogeneic haematopoietic stem cell transplantation (HSCT).
Joanna Dubelt   +8 more
core   +2 more sources

Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation [PDF]

open access: yesJournal of Hematotherapy & Stem Cell Research, 2002
Allogeneic hematopoietic stem cell transplantation (HSCT) is the most effective treatment for selected hematological malignancies. Its curative potential is largely mediated by an immune-mediated destruction of malignant cells by donor lymphocytes termed graft-versus-leukemia (GVL) effect.
Baron, Frédéric, Beguin, Yves
openaire   +3 more sources

Protection of stem cell-derived lymphocytes in a primate AIDS gene therapy model after in vivo selection [PDF]

open access: yes, 2009
Background: There is currently no effective AIDS vaccine, emphasizing the importance of developing alternative therapies. Recently, a patient was successfully transplanted with allogeneic, naturally resistant CCR5-negative (CCR5 delta 32) cells, setting ...
Trobridge, Grant D.   +28 more
core   +2 more sources

Autologous Graft-versus-Tumor Effect: Reality or Fiction?

open access: yesAdvances in Hematology, 2016
In contrast to allogeneic hematopoietic stem cell transplantation, the current dogma is not an evidence of graft-versus-tumor effect in autologous hematopoietic stem cell transplantation; thus, it is assumed that autologous hematopoietic stem cell ...
Luis F. Porrata
doaj   +1 more source

Optimizing peripheral blood stem cells transplantation outcome through amend relapse and graft failure: a review of current literature

open access: yesExperimental Hematology & Oncology, 2017
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) has been considered as a valuable approach in treatment of numerous malignant and none malignant hematologic disorders. However, relapse and poor graft function (PGF) after allo-SCT remain to
Saeed Mohammadi   +8 more
doaj   +1 more source

Allogeneic Stem Cell Transplantation in Myelodysplastic Syndrome

open access: yes, 2020
Objectives:Myelodysplastic syndrome (MDS) is a clonal disease that progresses with cytopenias and has leukemia transformation. Allogeneic Stem Cell Transplantation (ASCT) is a curative treatment in MDS patients.
Osman İlhan   +20 more
core   +1 more source

Donor mesenchymal stem cells trigger chronic graft-versus-host disease following minor antigen-mismatched bone marrow transplantation [PDF]

open access: yes, 2012
Chronic graft-versus-host disease (cGVHD) is a complication after minor antigen mismatched bone marrow transplantation (BMT) characterized by an autoimmune-type reaction in various organs.
Yumi Matsuzaki   +12 more
core  

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