Results 51 to 60 of about 6,115,227 (208)
Allogeneic Stem Cell Transplantation for Myelofibrosis in 2012 [PDF]
Summary Myelofibrosis ( MF ) is a heterogeneous disease for which long‐term, effective medical therapeutic options are currently limited. The role of allogeneic haematopoietic stem cell transplant ( AHSCT ) in this population, many of ...
McLornan, Donal +3 more
openaire +5 more sources
Antisense oligonucleotides (ASOs), including splice-switching oligonucleotides (SSOs), are promising therapeutic approaches for targeting genetic defects.
H. Yesid Estupiñán +12 more
doaj +1 more source
Allogeneic stem cell transplantation in follicular lymphoma [PDF]
Myeloablative allogeneic transplantation in follicular lymphoma has been found to be particularly effective in patients with relapsed disease and an inadequate bone marrow reserve or massive bone marrow involvement. Allogeneic transplantation carries the promise of long-term disease control by graft-versus-lymphoma immunity but is associated with a 30%-
openaire +2 more sources
Cerebral toxoplasmosis after haematopoietic stem cell transplantation [PDF]
Toxoplasmosis is an opportunistic infection caused by the parasite Toxoplasma gondii. The infection is severe and difficult to diagnose in patients receiving allogeneic haematopoietic stem cell transplantation (HSCT).
Joanna Dubelt +8 more
core +2 more sources
Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation [PDF]
Allogeneic hematopoietic stem cell transplantation (HSCT) is the most effective treatment for selected hematological malignancies. Its curative potential is largely mediated by an immune-mediated destruction of malignant cells by donor lymphocytes termed graft-versus-leukemia (GVL) effect.
Baron, Frédéric, Beguin, Yves
openaire +3 more sources
Protection of stem cell-derived lymphocytes in a primate AIDS gene therapy model after in vivo selection [PDF]
Background: There is currently no effective AIDS vaccine, emphasizing the importance of developing alternative therapies. Recently, a patient was successfully transplanted with allogeneic, naturally resistant CCR5-negative (CCR5 delta 32) cells, setting ...
Trobridge, Grant D. +28 more
core +2 more sources
Autologous Graft-versus-Tumor Effect: Reality or Fiction?
In contrast to allogeneic hematopoietic stem cell transplantation, the current dogma is not an evidence of graft-versus-tumor effect in autologous hematopoietic stem cell transplantation; thus, it is assumed that autologous hematopoietic stem cell ...
Luis F. Porrata
doaj +1 more source
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) has been considered as a valuable approach in treatment of numerous malignant and none malignant hematologic disorders. However, relapse and poor graft function (PGF) after allo-SCT remain to
Saeed Mohammadi +8 more
doaj +1 more source
Allogeneic Stem Cell Transplantation in Myelodysplastic Syndrome
Objectives:Myelodysplastic syndrome (MDS) is a clonal disease that progresses with cytopenias and has leukemia transformation. Allogeneic Stem Cell Transplantation (ASCT) is a curative treatment in MDS patients.
Osman İlhan +20 more
core +1 more source
Donor mesenchymal stem cells trigger chronic graft-versus-host disease following minor antigen-mismatched bone marrow transplantation [PDF]
Chronic graft-versus-host disease (cGVHD) is a complication after minor antigen mismatched bone marrow transplantation (BMT) characterized by an autoimmune-type reaction in various organs.
Yumi Matsuzaki +12 more
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