Results 41 to 50 of about 6,115,227 (208)

The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor [PDF]

open access: yes, 2013
Mobilized blood has supplanted bone marrow (BM) as the primary source of hematopoietic stem cells for autologous and allogeneic stem cell transplantation.
Dembowsky, K.   +38 more
core   +1 more source

Haematopoietic cell transplantation in Switzerland, changes and results over 20 years: a report from the Swiss Blood Stem Cell Transplantation Working Group for Blood and Marrow Transplantation registry 1997-2016 [PDF]

open access: yes, 2018
In 1997, the Swiss Blood Stem Cell Transplantation Group (SBST) initiated a mandatory national registry for all haematopoietic stem cell transplants (HCTs) in Switzerland.
Bargetzi, M.   +94 more
core   +2 more sources

Therapeutic choices in patients with Ph-Positive chronic myelogenous leukemia in Mexico in the era of tyrosine kinase inhibitors: stem cell transplantation or tyrosine kinase inhibitors? Fifteen years later

open access: yesRevista de Investigación Clínica
Background: Chronic myelogenous leukemia is a neoplastic proliferation of the granulocytic series. In Mexico, chronic myelogenous leukemia accounts for approximately 10% of all leukemias.
Max Robles-Nasta   +8 more
doaj   +1 more source

Acellular allogeneic nerve grafting combined with bone marrow mesenchymal stem cell transplantation for the repair of long-segment sciatic nerve defects: biomechanics and validation of mathematical models

open access: yesNeural Regeneration Research, 2016
We hypothesized that a chemically extracted acellular allogeneic nerve graft used in combination with bone marrow mesenchymal stem cell transplantation would be an effective treatment for long-segment sciatic nerve defects.
Ya-jun Li   +4 more
doaj   +1 more source

CD4+CD25+FOXP3+ T regulatory cells reconstitute and accumulate in the bone marrow of patients with multiple myeloma following allogeneic stem cell transplantation

open access: yesHaematologica, 2008
Background Very little is known about the number and function of immunosuppressive CD4+CD25+FOXP3+ T regulatory cells (Treg) in the human bone marrow and it is unclear whether bone marrow-residing Treg are capable of regenerating following allogeneic ...
Djordje Atanackovic   +12 more
doaj   +1 more source

Evading the Immune System: Immune Modulation and Immune Matching in Cell Replacement Therapies for Parkinson’s Disease

open access: yesJournal of Parkinson’s Disease, 2021
Stem cell-based therapies for Parkinson’s disease are now being applied clinically. Notably, studies have shown that controlling the graft-induced immune response improves the results.
Asuka Morizane, Jun Takahashi
doaj   +1 more source

Allogeneic stem cell transplantation for thalassemia major

open access: yesHaematologica, 2008
Allogeneic hemopoietic stem cell (HSC) transplantation in thalassemia major has been a cornerstone of the development of cell-based therapies[1][1] and a matter of passionate debate during the ‘80s and early ‘90s.[2][2] The aim of HSC transplantation in thalassemia is to replace the ...
Emanuele Angelucci, Donatella Baronciani
openaire   +3 more sources

Donation and transplantation of allogeneic hematopoietic stem cells [PDF]

open access: yesCanadian Medical Association Journal, 2011
Only 30% of patients with indications for a transplant have a matched related donor; the remaining 70% seek an unrelated donor on the world’s registry. Nonwhite Canadians have a particularly low likelihood of finding a match.1,2 Appendix 1 lists common indications for transplant (available at ...
Ilana, Kopolovic, Robert, Turner
openaire   +2 more sources

Haematopoietic stem cell transplantation: activity in Switzerland compared with surrounding European countries [PDF]

open access: yes, 2013
Haematopoietic stem cell transplantation (HSCT) is a highly specialised procedure used to treat malignancies of the lymphohaematopoietic system as well as some acquired and inherited disorders of the blood.
Gratwohl, A   +70 more
core   +1 more source

Allogeneic Stem Cell Transplantation for Aplastic Anemia

open access: yesBiology of Blood and Marrow Transplantation, 2007
Aplastic anemia encompasses a heterogeneous group of diseases with distinct pathophysiologies and a common clinical endpoint of marrow failure. Patients with severe aplastic anemia can be treated with immunosuppressive therapy (IST) or hematopoietic stem cell transplantation (HSCT).
Armand, Philippe, Antin, Joseph H.
openaire   +2 more sources

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