Results 31 to 40 of about 6,115,227 (208)

Host-directed therapies for tuberculous pericarditis

International Journal of Infectious Diseases, 2015
TB Pericarditis is associated with significant inflammatory and immune responses which can paradoxically cause injury to the pericardium and myocardium. Management with anti-TB therapy alone does not prevent complications or reduce mortality.
Alimuddin Zumla, Markus Maeurer, Guido Moll, Bongani M. Mayosi   +3 more
doaj   +1 more source

Efficient lysis of rhabdomyosarcoma cells by cytokine-induced killer cells : implications for adoptive immunotherapy after allogeneic stem cell transplantation [PDF]

, 2010
Background: Rhabdomyosarcoma is the most common soft tissue sarcoma in childhood and has a poor prognosis. Here we assessed the capability of ex vivo expanded cytokine-induced killer cells to lyse both alveolar and embryonic rhabdomyosarcoma cell lines ...
H. Kreyenberg, Gerrit Weber, S. Kloss, Bader, Peter, Koscielniak, Ewa, A. Willasch, Selim Kuci, T. Klingebiel, E. Koscielniak, Laer, Dorothee von, Miriam Stais, Willasch, Andre Manfred, D. von Laer, Klingebiel, Thomas, Klöß, Stephan, Stais, Miriam, Kuçi, Selim, Peter Bader, Eva Rettinger, Thomas Klingebiel, B. Voss, Z. Kuci, Kreyenberg, Hermann, Stephan Klöss, G. Weber, Dorothee Von Laer, E. Rettinger, Zyrafete Kuci, Kuçi, Zyrafete, Rettinger, Eva, Bernhard Voss, M. Stais, P. Bader, Hermann Kreyenberg, Weber, Gerrit, Voß, Bernhard, Ewa Koscielniak, Andre Willasch, S. Kuci   +38 more
core   +1 more source

Heme oxygenase-1: Equally important in allogeneic hematopoietic stem cell transplantation and organ transplantation? [PDF]

, 2021
The intracellular enzyme heme oxygenase-1 (HO-1) is responsible for the degradation of cell-free (cf) heme. Cfheme, released upon cell damage and cell death from hemoglobin, mitochondria and myoglobin, functions as a powerful damage-associated molecular ...
Verheij, Myrddin, Zeerleder, Sacha, Voermans, Carlijn, Sacha Zeerleder, Myrddin Verheij, Carlijn Voermans   +5 more
core   +1 more source

Allogeneic hematopoietic stem cell transplantation in Tunisia [PDF]

Bone Marrow Transplantation, 2008
In 1998, the Tunisian team of the 'Centre National de Greffe de Moelle Osseuse' initiated allogeneic hematopoietic SCT (AHSCT) in Tunisia. As of June 2007, information was collected about 299 patients with a first AHSCT and 12 additional retransplants. The median age was 19 years (range 2-49 years). The main indications were aplastic anemia (n=106, 36%)
T, Ben Othman, L, Torjemane, A, Abdelkefi, A, Lakhal, S, Ladeb, L, Ben Hamed, H, Slama, A, Ben Abdeladhim   +7 more
openaire   +2 more sources

Adoptive Immunotherapy in Chimeras with Donor Lymphocytes [PDF]

, 2003
Allogeneic stem cell transplantation has a well-defined indication in the treatment of hematological malignancies. The beneficial immune effect of allogeneic marrow transplantation has long been known, but only recently have methods been developed to ...
Kolb, Hans-Jochem, Roskrow, Marie, Guenther, Wolfgang, Schmid, Christoph, Ledderose, Georg, Weber, Martin, Chen, Xiao, Schleuning, Michael, Woiciechowski, Anja   +8 more
core   +1 more source

Risk factors for relapse after allogeneic transplantation in acute myeloid leukemia

Haematologica, 2016
Acute myeloid leukemia is a clonal neoplasm derived from myeloid progenitor cells with a varying outcome. The initial goal of treatment is the achievement of complete remission, defined for over 40 years by morphology.
Gert J. Ossenkoppele, Jeroen J.W.M. Janssen, Arjan A. van de Loosdrecht   +2 more
doaj   +1 more source

Alemtuzumab in allogeneic hematopoetic stem cell transplantation [PDF]

Expert Opinion on Biological Therapy, 2011
With the use of reduced-intensity conditioning (RIC), early toxicity of allogeneic stem cell transplantation (SCT) has been much reduced. Graft-versus-host disease (GvHD) causes morbidities and mortality. Alemtuzumab is a mAb directed against CD52. When administered prior to transplant, it leads to T-cell depletion.
Xavier, Poiré, Koen, van Besien
openaire   +2 more sources

Adoptive transfer of cytomegalovirus-specific CTL to stem cell transplant patients after selection by HLA–peptide tetramers [PDF]

, 2005
Stem cell transplantation is used widely in the management of a range of diseases of the hemopoietic system. Patients are immunosuppressed profoundly in the early posttransplant period, and reactivation of cytomegalovirus (CMV) remains a significant ...
Premini Mahendra, Craddock, Charles., McDonald, D, Billingham, Lucinda, Steward, Colin, Dorothy McDonald, Pourgheysari, Batoul, Eduardo Olavarria, Mahendra, Premini, Assenmacher, Mario., Olavarria, Eduardo, Tauro, Sudhir, Chakraverty, Ronjon., Goldman, John, Cobbold, Mark., Moss, Paul; id_orcid, Steward, Colin., McDonald, Dorothy, Pourgheysari Najafabadi, Batoul, John Goldman, Ronjon Chakraverty, Chakraverty, Ronjon, Crawley, Charles, Colin Steward, Billingham, Lucinda; id_orcid, Craddock, Charles; id_orcid, Assenmacher, Mario, Goldman, J, Pourgheysari, Batoul., Billingham, Lucinda., Tauro, S, Crawley, Charles., Charles Crawley, Osman, H, Batoul Pourgheysari, Naeem Khan, Mario Assenmacher, Osman, Husam, Assenmacher, M, Khan, Naeem, Goldman, John., Craddock, Charles, Mark Cobbold, Steward, C, McDonald, Dorothy., Olavarria, Eduardo., Olavarria, E, Husam Osman, Cobbold, Mark, Crawley, C, Osman, Husam., Mahendra, Premini., Sudhir Tauro, Tauro, Sudhir., Charles Craddock, Moss, Paul A. H., Moss, Paul A H, Khan, Naeem., Lucinda Billingham, Paul A.H. Moss, Moss, Paul A.H.   +60 more
core   +1 more source

Impact of different post-remission strategies on quality of life in patients with acute myeloid leukemia

Haematologica, 2008
Background The impact on quality of life of allogeneic stem cell transplantation or conventional chemotherapy in patients with acute myeloid leukemia remains unclear, mainly because of a lack of studies with long-term follow-up. The German AML-Intergroup,
Dorle Messerer, Jutta Engel, Joerg Hasford, Markus Schaich, Gerhard Ehninger, Cristina Sauerland, Thomas Büchner, Andrea Schumacher, Rainer Krahl, Dietger Niederwieser, Jürgen Krauter, Arnold Ganser, Ursula Creutzig, Hartmut Döhner, Richard F. Schlenk   +14 more
doaj   +1 more source

Risks and benefits of sex-mismatched hematopoietic cell transplantation differ according to conditioning strategy

Haematologica, 2015
Sex-mismatched hematopoietic cell transplantation is linked to increased graft-versus-host disease and mortality in myeloablative conditioning. Here we evaluated outcomes of 1,041 adult transplant recipients at two centers between 2006 and 2013 and ...
Hideki Nakasone, Mats Remberger, Lu Tian, Petter Brodin, Bita Sahaf, Fang Wu, Jonas Mattsson, Robert Lowsky, Robert Negrin, David B. Miklos, Everett Meyer   +10 more
doaj   +1 more source