Results 21 to 30 of about 96,199 (216)

Autologous transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia achieves outcomes similar to allogeneic transplantation: results of CALGB Study 10001 (Alliance)

Haematologica, 2014
Allogeneic stem cell transplantation is the standard approach to Philadelphia chromosome positive acute lymphoblastic leukemia. We hypothesized that imatinib plus sequential chemotherapy will result in significant leukemia cell cytoreduction in patients ...
Meir Wetzler, Dorothy Watson, Wendy Stock, Gregory Koval, Flora A. Mulkey, Eva E. Hoke, John M. McCarty, William G. Blum, Bayard L. Powell, Guido Marcucci, Clara D. Bloomfield, Charles A. Linker, Richard A. Larson   +12 more
doaj   +1 more source

Host-directed therapies for tuberculous pericarditis

International Journal of Infectious Diseases, 2015
TB Pericarditis is associated with significant inflammatory and immune responses which can paradoxically cause injury to the pericardium and myocardium. Management with anti-TB therapy alone does not prevent complications or reduce mortality.
Alimuddin Zumla, Markus Maeurer, Guido Moll, Bongani M. Mayosi   +3 more
doaj   +1 more source

Risk factors for relapse after allogeneic transplantation in acute myeloid leukemia

Haematologica, 2016
Acute myeloid leukemia is a clonal neoplasm derived from myeloid progenitor cells with a varying outcome. The initial goal of treatment is the achievement of complete remission, defined for over 40 years by morphology.
Gert J. Ossenkoppele, Jeroen J.W.M. Janssen, Arjan A. van de Loosdrecht   +2 more
doaj   +1 more source

Allogeneic hematopoietic stem cell transplantation in Tunisia [PDF]

Bone Marrow Transplantation, 2008
In 1998, the Tunisian team of the 'Centre National de Greffe de Moelle Osseuse' initiated allogeneic hematopoietic SCT (AHSCT) in Tunisia. As of June 2007, information was collected about 299 patients with a first AHSCT and 12 additional retransplants. The median age was 19 years (range 2-49 years). The main indications were aplastic anemia (n=106, 36%)
T, Ben Othman, L, Torjemane, A, Abdelkefi, A, Lakhal, S, Ladeb, L, Ben Hamed, H, Slama, A, Ben Abdeladhim   +7 more
openaire   +2 more sources

Impact of different post-remission strategies on quality of life in patients with acute myeloid leukemia

Haematologica, 2008
Background The impact on quality of life of allogeneic stem cell transplantation or conventional chemotherapy in patients with acute myeloid leukemia remains unclear, mainly because of a lack of studies with long-term follow-up. The German AML-Intergroup,
Dorle Messerer, Jutta Engel, Joerg Hasford, Markus Schaich, Gerhard Ehninger, Cristina Sauerland, Thomas Büchner, Andrea Schumacher, Rainer Krahl, Dietger Niederwieser, Jürgen Krauter, Arnold Ganser, Ursula Creutzig, Hartmut Döhner, Richard F. Schlenk   +14 more
doaj   +1 more source

Risks and benefits of sex-mismatched hematopoietic cell transplantation differ according to conditioning strategy

Haematologica, 2015
Sex-mismatched hematopoietic cell transplantation is linked to increased graft-versus-host disease and mortality in myeloablative conditioning. Here we evaluated outcomes of 1,041 adult transplant recipients at two centers between 2006 and 2013 and ...
Hideki Nakasone, Mats Remberger, Lu Tian, Petter Brodin, Bita Sahaf, Fang Wu, Jonas Mattsson, Robert Lowsky, Robert Negrin, David B. Miklos, Everett Meyer   +10 more
doaj   +1 more source

Donation and transplantation of allogeneic hematopoietic stem cells [PDF]

Canadian Medical Association Journal, 2011
Only 30% of patients with indications for a transplant have a matched related donor; the remaining 70% seek an unrelated donor on the world’s registry. Nonwhite Canadians have a particularly low likelihood of finding a match.1,2 Appendix 1 lists common indications for transplant (available at ...
Ilana, Kopolovic, Robert, Turner
openaire   +2 more sources

Acellular allogeneic nerve grafting combined with bone marrow mesenchymal stem cell transplantation for the repair of long-segment sciatic nerve defects: biomechanics and validation of mathematical models

Neural Regeneration Research, 2016
We hypothesized that a chemically extracted acellular allogeneic nerve graft used in combination with bone marrow mesenchymal stem cell transplantation would be an effective treatment for long-segment sciatic nerve defects.
Ya-jun Li, Bao-lin Zhao, Hao-ze Lv, Zhi-gang Qin, Min Luo   +4 more
doaj   +1 more source

Evading the Immune System: Immune Modulation and Immune Matching in Cell Replacement Therapies for Parkinson’s Disease

Journal of Parkinson’s Disease, 2021
Stem cell-based therapies for Parkinson’s disease are now being applied clinically. Notably, studies have shown that controlling the graft-induced immune response improves the results.
Asuka Morizane, Jun Takahashi
doaj   +1 more source

Therapeutic choices in patients with Ph-Positive chronic myelogenous leukemia in Mexico in the era of tyrosine kinase inhibitors: stem cell transplantation or tyrosine kinase inhibitors? Fifteen years later

Revista de Investigación Clínica
Background: Chronic myelogenous leukemia is a neoplastic proliferation of the granulocytic series. In Mexico, chronic myelogenous leukemia accounts for approximately 10% of all leukemias.
Max Robles-Nasta, Daniela Sánchez-Bonilla, Moises M. Gallardo-Pérez, Edgar J. Hernández-Flores, Merittzel A. Montes-Robles, María de L. Pastelín-Martínez, Juan C. Olivares-Gazca, Guillermo J. Ruiz-Delgado, Guillermo J. Ruiz-Argüelles   +8 more
doaj   +1 more source