Results 41 to 50 of about 11,297 (212)
Alloimmune T cells in transplantation [PDF]
Journal of Clinical Investigation, 2017 Alloimmune T cells are central mediators of rejection and graft-versus-host disease in both solid organ and hematopoietic stem cell transplantation. Unique among immune responses in terms of its strength and diversity, the T cell alloresponse reflects extensive genetic polymorphisms between allogeneic donors and recipients, most prominently within the ...
Megan Sykes, Susan DeWolf
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Current status of alloimmunity [PDF]
Current Opinion in Nephrology and Hypertension, 2016 The present review aims to highlight the major recent advances in transplantation with regards to basic, translational, and clinical research.We describe new concepts in understanding allorecognition and allospecificity of T cells, and discuss current challenges in targeting memory T cells, including the limitation of rodent disease models.
Naoka Murakami +2 more
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Role of RBC's alloimmunization in multiple transfused thalassaemia patients [PDF]
, 2016 Background: Appropriate and regular red cell transfusion remains the main treatment of choice for a large number of patients with multiple transfusions. This study has been carried out to assess the prevalence of and to provide frequency and distribution
Gamit, Sejal +2 more
core +2 more sources
Frontiers in Medicine, 2021 Patients with sickle cell disease often undergo frequent blood transfusions. This increases their exposure to red blood cell alloantigens of donor units, thus making it more likely that they produce alloantibodies.
Salomé Conrath +5 more
semanticscholar +1 more source
The severity of illness and inflammatory markers cannot predict red blood cell alloimmunization in cancer patients [PDF]
, 2015 38738
Castilho, Lilian
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Allopeptides and the alloimmune response [PDF]
Cellular Immunology, 2007 The inherent ability of the host immune system to distinguish between self- and non-self forms the basis of allorecognition. T lymphocytes constitute the most important effector arm of allorecognition. Here we describe the fundamentals of direct and indirect pathways by which allopeptides are presented to effector T cells.
T. Mohanakumar, Ankit Bharat
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Use of Rituximab in autoimmune hemolytic anemia associated with non-hodgkin lymphomas [PDF]
, 2011 The association between non-Hodgkin lymphomas and autoimmune disorders is a well-known event. Also autoimmune hemolytic anemia (AHA), although much more frequent in patients with chronic lymphocytic leukemia (CLL), has been described in this group of ...
Fozza, Claudio +1 more
core +3 more sources
Main erythrocyte antigens involved in the alloimmunization process [PDF]
, 2020 Erythrocyte alloimmunization occurs when an individual produces antibodies to antigens on the donor's red blood cell, which the immune system identifies as a foreign element to the organism.
de Oliveira, Mário Cézar +1 more
core +2 more sources
Scientific Reports, 2020 The development of hemolytic erythrocyte alloantibodies and autoantibodies complicates transfusion therapy in thalassemia patients. These antibodies ultimately increase the need for blood and intensify transfusion complications. There is a scanty data on
A. El‐Beshlawy +4 more
semanticscholar +1 more source
British Journal of Haematology, 2018 Despite the significance of red blood cell (RBC) alloimmunization, the lack of standardized registries in the US has prevented the completion of large studies.
M. Karafin +9 more
semanticscholar +1 more source