Results 41 to 50 of about 12,433 (252)

Hemolytic Disease of the Fetus and Newborn due to Intravenous Drug Use

American Journal of Perinatology Reports, 2016
Objectives The objective is to present a pregnancy complication associated with intravenous drug use, namely, that of red blood cell alloimmunization and hemolytic disease of the fetus and newborn.
Kara B. Markham, Scott R. Scrape, Mona Prasad, Karen Q. Rossi, Richard W. O'Shaughnessy   +4 more
doaj   +1 more source

Red Blood Cell Alloimmunization in Pediatric group with Beta Thalassemia: A Five-Year Experience

Global Pediatric Health, 2022
Beta-thalassemia is one of the most frequently occurring hematological disorders in [Removed for blinded peer-review]. Regular blood transfusion is required in almost all cases for management.
Kiran Minhas MBBS FCPS, Muzamil Shabana Ejaz MBBS MCPS DCH FCPS, Alaa Tukruna MD, Maryam Haider MBBS FCPS, Aabiya Arif MBBS, Sameer Saleem Tebha MBBS   +5 more
doaj   +1 more source

The adverse impact on liver transplantation of using positive cytotoxic crossmatch donors [PDF]

, 1992
Because of the liver graft's ability to resist cytotoxic antibody-mediated rejection, it has become dogma that the conventional transplant crossmatch used to avoid hyperacute rejection of other organs is irrelevant to the liver.
Abu-Elmagd, K, Bronsther, O, Demetris, AJ, Fung, JJ, Iwaki, Y, Kobayashi, M, Nakamura, K, Starzl, TE, Takaya, S, Todo, S, Tzakis, AG, Yagihashi, A   +11 more
core   +1 more source

Altered type 1 interferon responses in alloimmunized and nonalloimmunized patients with sickle cell disease

eJHaem, 2021
Patients with sickle cell disease (SCD) have a high prevalence of RBC alloimmunization. However, underlying mechanisms are poorly understood. Given that proinflammatory type 1 interferons (IFNα/β) and interferon stimulated genes (ISGs) promote ...
Emaan Madany, June Lee, Chelsea Halprin, Jina Seo, Nicole Baca, Fataneh Majlessipour, Jeanne E. Hendrickson, Samuel H. Pepkowitz, Chelsea Hayes, Ellen Klapper, David R. Gibb   +10 more
doaj   +1 more source

Routine Fetal Rhd Genotyping with Maternal Plasma: A Four-Year Experience in Belgium [PDF]

, 2008
peer reviewedBACKGROUND: The objective was to evaluate the diagnostic value of RHD fetal genotyping from the plasma of D- mothers as soon as 10 weeks' gestation in a routine clinical practice in Belgium.
Bianchi DW, Colin Y, Cortey A, Daniels G, Flegel WA, Flegel WA, Grootkerk MG, Judd WJ, Legler J, Mannessier L, Minon JM, Moise KJ, Moise KJ, Singleton BK, Wagner FF, Wagner FF   +15 more
core   +1 more source

Neonatal alloimmune thrombocytopenia

BMJ, 2003
Neonatal alloimmune thrombocytopenia—caused by movement of maternal alloantibodies directed against fetal platelet antigens across the placenta—is the most common cause of severe neonatal thrombocytopenia.1 These alloantibodies cause thrombocytopenia, which may result in intracranial haemorrhage.2 3 Most cases arise unexpectedly, and prompt diagnosis ...
R, Rayment, J, Birchall, H, Yarranton, J, Hewertson, D, Allen, M F, Murphy, D J, Roberts   +6 more
openaire   +3 more sources

Treatments for hematologic malignancies in contrast to those for solid cancers are associated with reduced red cell alloimmunization

Haematologica, 2017
Red cell alloimmunization may induce severe hemolytic side effects. Identification of risk-modifying conditions will help tailor preventative strategies.
Dorothea Evers, Jaap Jan Zwaginga, Janneke Tijmensen, Rutger A. Middelburg, Masja de Haas, Karen M.K. de Vooght, Daan van de Kerkhof, Otto Visser, Nathalie C.V. Péquériaux, Francisca Hudig, Johanna G. van der Bom   +10 more
doaj   +1 more source

Alloimmunization in multitransfused liver disease patients: Impact of underlying disease

Asian Journal of Transfusion Science, 2016
Introduction: Transfusion support is vital to the management of patients with liver diseases. Repeated transfusions are associated with many risks such as transfusion-transmitted infection, transfusion immunomodulation, and alloimmunization.
Meenu Bajpai, Shruti Gupta, Priyanka Jain   +2 more
doaj   +1 more source

TRANSFUSION PRACTICE, POST-TRANSFUSION COMPLICATIONS AND RISK FACTORS IN SICKLE CELL DISEASE IN SENEGAL, WEST AFRICA.

Mediterranean Journal of Hematology and Infectious Diseases, 2022
Context and Objectives: Blood transfusions (BT) remain a mainstay of therapy for patients with sickle cell disease (SCD), but pose significant clinical challenges. We aim to assess infectious markers, red cell alloimmunization and iron overload secondary
Moussa Seck, Alioune Badara Senghor, Mossane Loum, Sokhna Aissatou Touré, Blaise Félix Faye, Alioune Badara Diallo, Mohamed Keita, Elimane Seydi Bousso, Sérigne Mourtalla Guèye, Macoura Gadji, Abibatou Sall, Awa Oumar Touré, Saliou Diop   +12 more
doaj   +1 more source

Prenatal Exome Sequencing Identifies Dual Maternal‐Fetal Diagnosis of HbF Mission Bay, a Novel HBG2 Variant Associated With Methemoglobinemia, Hypoxia and Hemolytic Anemia

Prenatal Diagnosis, EarlyView.
ABSTRACT Prenatal exome sequencing (ES) can establish rare genetic diagnoses in a fetus but may also lead to occult genetic diagnosis in a biological parent. We present a case of dual fetal and maternal diagnosis by prenatal ES, in a fetus with unexplained anemia and in a pregnant patient with sickle cell disease (SCD) and recurrent unexplained hypoxia.
Matthew A. Shear, Billie Lianoglou, Ugur Hodoglugil, W. Patrick Devine, Ashutosh Lal, Juan Gonzalez, Teresa N. Sparks   +6 more
wiley   +1 more source