Results 71 to 80 of about 11,297 (212)
Abstract Background Low‐titer O whole blood (LTOWB) is commonly used in the United States for severe bleeding. Our objective was to examine disparities in LTOWB utilization and its association with survival. Study Design and Methods This retrospective analysis included patients receiving at least 1 L of red blood cells (RBC) or LTOWB in the first 4 h ...
Skye Clayton+5 more
wiley +1 more source
Abstract Background Early detection and intervention for fetal hemolytic disease are essential to prevent severe complications. This study evaluates the antenatal and postnatal clinical and laboratory characteristics of newborns who underwent intrauterine intravascular transfusion due to anti‐D‐induced hemolytic disease. Study Design and Methods Twenty
Altay Babacan+3 more
wiley +1 more source
Accuracy of Blood Group Typing in the Management and Prevention of Alloimmunization [PDF]
Blood transfusion is an effective therapeutic approach for several hematological conditions including sickle cell disease (SCD), thalassaemia, myelodysplastic syndrome (MDS), and autoimmune hemolytic anemia. It is also often indicated for transplantation
Rios, Maria+2 more
core +2 more sources
Type 1 Interferon Gene Signature Promotes RBC Alloimmunization in a Lupus Mouse Model
Red blood cell (RBC) transfusion exposes recipients to hundreds of unmatched minor RBC antigens. This exposure can lead to production of alloantibodies that promote clinically significant hemolytic events.
J. Lee+7 more
semanticscholar +1 more source
Abstract figure legend Metabolic stimulation improves bioenergetics, redox state, hydration and hematologic indices of circulating erythrocytes from sickle cell mice. Retained mitochondria in circulating RBCs from sickle mice are a source of RBC ATP as mitochondria function (ETC, electron transport chain) inhibitors [rotenone, a mitochondrial complex I
Luis E. F. Almeida+4 more
wiley +1 more source
Patients with sickle cell disease (SCD) often require red blood cell (RBC) transfusions but alloimmunization remains a significant complication. Alloantibodies can lead to delayed hemolytic transfusion reactions (DHTRs) days to weeks after a RBC ...
Sarita L Coleman+3 more
semanticscholar +1 more source
Role of complement in alloimmunization and hyperhemolysis
Purpose of review The purpose of this review is to summarize the role of complement in regulating the removal of a target alloantigen following an incompatible red blood cell (RBC) transfusion, the formation of alloantibodies following RBC alloantigen ...
S. Chonat+3 more
semanticscholar +1 more source
ABSTRACT Background After the identification of five novel feline erythrocyte antigens (FEAs) and evidence establishing FEA 1's immunogenicity, attempts to sensitize a cat to FEA 4 unexpectedly resulted in the production of alloantibodies directed against an unknown antigen, named FEA 6.
Félix Bajon+2 more
wiley +1 more source
Back to base pairs:What is the genetic risk for red bloodcell alloimmunization? [PDF]
core +3 more sources
Objective: Blood transfusion is a common lifesaving treatment but it is often complicated with alloimmunization. Previously studies in Greece have concentrated on alloimmunization in multiply transfused thalassemic patients or antenatal women.
M. Politou+7 more
semanticscholar +1 more source