Results 71 to 80 of about 11,297 (212)

Sex‐based disparities in low‐titer O whole blood utilization and mortality among severely injured trauma patients

open access: yesTransfusion, EarlyView.
Abstract Background Low‐titer O whole blood (LTOWB) is commonly used in the United States for severe bleeding. Our objective was to examine disparities in LTOWB utilization and its association with survival. Study Design and Methods This retrospective analysis included patients receiving at least 1 L of red blood cells (RBC) or LTOWB in the first 4 h ...
Skye Clayton   +5 more
wiley   +1 more source

Several features of newborns following intrauterine intravascular blood transfusion for fetal hemolytic disease caused by anti‐D alloimmunization

open access: yesTransfusion, EarlyView.
Abstract Background Early detection and intervention for fetal hemolytic disease are essential to prevent severe complications. This study evaluates the antenatal and postnatal clinical and laboratory characteristics of newborns who underwent intrauterine intravascular transfusion due to anti‐D‐induced hemolytic disease. Study Design and Methods Twenty
Altay Babacan   +3 more
wiley   +1 more source

Accuracy of Blood Group Typing in the Management and Prevention of Alloimmunization [PDF]

open access: yes, 2019
Blood transfusion is an effective therapeutic approach for several hematological conditions including sickle cell disease (SCD), thalassaemia, myelodysplastic syndrome (MDS), and autoimmune hemolytic anemia. It is also often indicated for transplantation
Rios, Maria   +2 more
core   +2 more sources

Type 1 Interferon Gene Signature Promotes RBC Alloimmunization in a Lupus Mouse Model

open access: yesFrontiers in Immunology, 2020
Red blood cell (RBC) transfusion exposes recipients to hundreds of unmatched minor RBC antigens. This exposure can lead to production of alloantibodies that promote clinically significant hemolytic events.
J. Lee   +7 more
semanticscholar   +1 more source

Metabolic stimulation improves bioenergetics and haematologic indices of circulating erythrocytes from sickle cell mice

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Metabolic stimulation improves bioenergetics, redox state, hydration and hematologic indices of circulating erythrocytes from sickle cell mice. Retained mitochondria in circulating RBCs from sickle mice are a source of RBC ATP as mitochondria function (ETC, electron transport chain) inhibitors [rotenone, a mitochondrial complex I
Luis E. F. Almeida   +4 more
wiley   +1 more source

Alloimmunization in patients with sickle cell disease and underrecognition of accompanying delayed hemolytic transfusion reactions

open access: yesTransfusion, 2019
Patients with sickle cell disease (SCD) often require red blood cell (RBC) transfusions but alloimmunization remains a significant complication. Alloantibodies can lead to delayed hemolytic transfusion reactions (DHTRs) days to weeks after a RBC ...
Sarita L Coleman   +3 more
semanticscholar   +1 more source

Role of complement in alloimmunization and hyperhemolysis

open access: yesCurrent opinion in hematology, 2020
Purpose of review The purpose of this review is to summarize the role of complement in regulating the removal of a target alloantigen following an incompatible red blood cell (RBC) transfusion, the formation of alloantibodies following RBC alloantigen ...
S. Chonat   +3 more
semanticscholar   +1 more source

Prevalence of a Novel Immunogenic Feline Erythrocyte Antigen (FEA 6) and Expression Patterns Between FEAs

open access: yesJournal of Veterinary Internal Medicine, Volume 39, Issue 3, May/June 2025.
ABSTRACT Background After the identification of five novel feline erythrocyte antigens (FEAs) and evidence establishing FEA 1's immunogenicity, attempts to sensitize a cat to FEA 4 unexpectedly resulted in the production of alloantibodies directed against an unknown antigen, named FEA 6.
Félix Bajon   +2 more
wiley   +1 more source

Retrospective Study on Prevalence, Specificity, Sex, and Age Distribution of Alloimmunization in Two General Hospitals in Athens

open access: yesTurkish journal of haematology : official journal of Turkish Society of Haematology, 2020
Objective: Blood transfusion is a common lifesaving treatment but it is often complicated with alloimmunization. Previously studies in Greece have concentrated on alloimmunization in multiply transfused thalassemic patients or antenatal women.
M. Politou   +7 more
semanticscholar   +1 more source

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