Results 71 to 80 of about 12,433 (252)

Clinical implications of imlifidase interference in antibody screening and transfusion management

Transfusion, EarlyView.
Abstract Background Imlifidase has received conditional approval from the EMA for desensitizing deceased donor kidney transplant recipients. It works by cleaving IgG into F(ab′)2 and Fc fragments, thereby reducing the risk of antibody‐mediated rejection. However, its impact on diagnostic assays remains understudied. Case Report We present the case of a
Zgjim Osmani, Aiko P. J. de Vries, Arjan Albersen   +2 more
wiley   +1 more source

Prevalence and Specificity of RBC Alloantibodies in Indian Patients Attending a Tertiary Care Hospital

Advances in Hematology, 2014
Background. Red blood cell (RBC) alloimmunization results from genetic disparity of RBC antigens between donor and recipients. Data about alloimmunization rate in general patient population is scarce especially from resource limited countries.
Shamsuz Zaman, Rahul Chaurasia, Kabita Chatterjee, Rakesh Mohan Thapliyal   +3 more
doaj   +1 more source

Fucosylation limits ADCC in clinically used anti‐RhD monoclonal antibodies

Transfusion, EarlyView.
Abstract Background Haemolytic disease of the fetus and newborn (HDFN) is caused by maternal alloantibodies, often targeting the D antigen on fetal red blood cells. Maternal immunization is preventable with timely administration of anti‐D polyclonal antibodies (pAbs).
Gabriela Koike, Albert Bondt, Douwe Schulte, Rien Leuvenink, Dirk Jan Mons, Peter C. Ligthart, E. Joanne T. Verweij, AFRICARhE Consortium, Enrico Lopriore, E. J. T. Joanne Verweij, Tienke Vermeiden, Thomas van den Akker, C. Ellen van der Schoot, Derek P. de Winter, Renske van Oever, Abera Kenay Tura, Tadesse Gure, Assefa Desalew, Tewodros Tesfa, Konjit Eshetu, Jeremia Pyuza, Rafiki N. Mjema, Priscus John Mapendo, Jeremiah John Hhera, Bariki Mchome, Patricia Swai, Blandina T. Mmbaga, Aisa Shayo, Peter Moons, Kondwani Kawaza, Luis Gadama, Albert J. R. Heck, C. Ellen van der Schoot, Gestur Vidarsson   +33 more
wiley   +1 more source

EFFECTS OF PROPHYLACTIC RED BLOOD CELL (RBC) TRANSFUSION WITH EXTENDED ANTIGEN MATCHING ON ALLOIMMUNIZATION IN PATIENTS WITH SICKLE CELL DISEASE (SCD)

Hematology, Transfusion and Cell Therapy, 2023
Background and aims: As the alloimmunization remains a major complication associated with RBC transfusions in SCD patients and can be associated with Delayed Hemolytic Transfusion Reactions (DHTRs), this study was undertaken to assess the effects of ...
I Leal, TDD Santos, L Castilho
doaj   +1 more source

Haemolytic Disease Of Foetus And Newborn And Haemolytic Transfusion Reaction Due To Kidd Antibody In Hospital Umum Sarawak [PDF]

, 2017
Penyakit Hemolisis Janin dan Bayi baru lahir (HDFN) dan penyakit Hemolitik Transfusi Darah (HTR) boleh disebabkan oleh antibodi terhadap antigen Kidd.
Mohd Yasin, Irni
core  

Neonatal alloimmune thrombocytopenia

Haematologica, 2008
Neonatal alloimmune thrombocytopenia is the commonest cause of early onset isolated thrombocytopenia in an otherwise healthy neonate.[1][1] This syndrome is comparable to hemolytic disease of the newborn, although it frequently affects the first infant.
openaire   +3 more sources

Red cell alloimmunization in multitransfused hepatobiliary patients at hospital Selayang

Asian Journal of Transfusion Science
BACKGROUND: Transfusion support is vital for the management of patients with hepatobiliary disease. Repeated blood transfusions increase the risk of alloimmunization, i.e., the development of alloantibodies, which might lead to difficulties in blood ...
Prasanthini Nahendran, Siti Balkis Budin, Nur Zakiah Mohd Saat, Mohd Faeiz Yusop, Tengku Norita Tengku Yazid, Nur Najmi Mohamad Anuar   +5 more
doaj   +1 more source

Antenatal risk estimation for exchange transfusions in neonates with hemolytic disease of the fetus and newborn in a changing treatment landscape: A multicenter, retrospective cohort study

Transfusion, EarlyView.
Abstract Background Neonates with hemolytic disease of the fetus and newborn (HDFN) may require exchange transfusions (ET) for severe hyperbilirubinemia. We evaluated if ET in neonates with HDFN was associated with the maximum maternal titer and antibody‐dependent cellular cytotoxicity (ADCC) and we determined the change in the number of hospitals ...
Derek P. de Winter, Masja de Haas, Christian V. Hulzebos, Michaël V. Lukens, Sandra A. Prins, Jasper V. Been, Esther J. d'Haens, Daniël C. Vijlbrief, Sabine L. A. G. Vrancken, Amanda M. P. Trompenaars, Huib Ceelie, Lieke M. J. van Zogchel, Annemiek M. C. P. Joosen, Clemens B. Meijssen, J. L. A. M. van Hillegersberg, Janneke C. Zant, Maaike C. van Rossem, Ron van Beek, Helene G. Stas, Clare E. Counsilman, F. R. Knol, I. A. M. Schiering, Gerdina H. Dubbink‐Verheij, E. J. T. Verweij, Enrico Lopriore, for the WISE investigators, Ron van Beek, A.J. (Adriaan) van Gammeren, Sandra A. Prins, J.H. Klinkspoor, Jasper V. Been, Henk Russcher, Clare E. Counsilman, Sietske Hogenboom, Huib Ceelie, Angelique Hoffmann‐Haringsma, Gerdina H. Dubbink‐Verheij, Jacques J.H. Hens, Esther J. d'Haens, Gijs den Besten, Lieke M.J. van Zogchel, N.C.V. Péquériaux, Derek P. de Winter, E.J.T. (Joanne) Verweij, Masja de Haas, Enrico Lopriore, Helene G. Stas, Floor Weerkamp, Amanda M.P. Trompenaars, Tinta J.F. Lebon, Annemiek M.C.P. Joosen, Peter Andriessen, Clemens B. Meijssen, Karlijn Gijzen, F.R. Knol, Janneke C. Zant, Geert Jan Blok, Sabine L.A.G. Vrancken, Annegeet van den Bos, Maaike C. van Rossem, Jolanda Lamberts, I.A.M. Schiering, Claudia Admiraal, J.L.A.M. van Hillegersberg, Daniël C. Vijlbrief, Karen M.K. De Vooght, Christian V. Hulzebos, Michaël V. Lukens   +67 more
wiley   +1 more source

Platelet Biochemistry and Morphology after Cryopreservation [PDF]

, 2020
Platelet cryopreservation has been investigated for several decades as an alternative to room temperature storage of platelet concentrates. The use of dimethylsulfoxide as a cryoprotectant has improved platelet storage and cryopreserved concentrates can ...
Compernolle, Veerle, Feys, Hendrik, Six, Katrijn   +2 more
core   +1 more source

Novel method for trend change detection and hypothesis generation in hemovigilance: A transfusion‐related immunomodulation and blood production changes study

Transfusion, EarlyView.
Abstract Background Immunomodulatory consequences of transfusion, known as transfusion‐related immune modulation (TRIM), impact patients but are not captured by hemovigilance systems. This study's objective is to explore TRIM impacts of production changes made by the blood supplier. Methods We included all transfused and non‐transfused adult inpatients
S. Ning, N. Li, Y. Liu, D. Kim, J. P. Acker, D. Arnold, M. Hadzi‐Tosev, C. Hillis, A. Kauffman, K. J. Lucier, P. C. Liaw, B. Rochwerg, S. Syed, G. Travis, M. Zeller, N. M. Heddle   +15 more
wiley   +1 more source