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2004
Allorecognition refers to detection by the immune system of genetically encoded polymorphisms between members of the same species. Following transplantation of allogeneic tissues, recognition by recipient T lymphocytes of foreign proteins expressed by donor cells (T-cell allorecognition) initiates a cascade of immunological reactions resulting in rapid
Gilles Benichou +4 more
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Allorecognition refers to detection by the immune system of genetically encoded polymorphisms between members of the same species. Following transplantation of allogeneic tissues, recognition by recipient T lymphocytes of foreign proteins expressed by donor cells (T-cell allorecognition) initiates a cascade of immunological reactions resulting in rapid
Gilles Benichou +4 more
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HUMAN HEART ENDOTHELIAL-CELL-RESTRICTED ALLORECOGNITION
Transplantation, 1996We studied the reactivity of cardiac graft-infiltrating cells, cultured from endomyocardial biopsy specimens, toward heart endothelial cells (Hec). In two cases, Hec derived from the specific donor heart or Hec compatible with the donor were lysed, but not the syngeneic B cell line. A vessel-derived endothelial cell line was not lysed.
N H, Jutte +6 more
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Direct and Indirect Allorecognition
2006The design and effectiveness of strategies to promote long-term graft acceptance requires a fundamental understanding of the mechanisms underlying acute and chronic rejection. This chapter discusses the two pathways of allorecognition--direct and indirect--and suggests that the direct pathway plays a major role in the early weeks after transplantation ...
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Allorecognition Between Compound Ascidian Colonies
Zoological Science, 2013The compound ascidian Botryllus schlosseri reproduces asexually, and forms colonies to adhere to matrices such as rocks. This species has developed a mechanism to distinguish between self stem cells and invasive parasitizing nonself cells from other individuals of the same species, probably as a defense against parasitism. It is highly likely that such
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Involvement of the CDw50 molecule in allorecognition
Tissue Antigens, 1990Abstract: The CDw50 differentiation antigen is defined by 101–1D2 and 140–11 monoclonal antibodies (mAb), both produced and characterized in our laboratory. This molecule is broadly expressed on hematopoetic cells but not on other cells. In this report we show that these 2 mAb recognize different epitopes of the same molecule, which are resistant to ...
R, Vilella +5 more
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Allorecognition polymorphism versus parasitic stem cells
Trends in Genetics, 2006Allorecognition--the ability of an individual to distinguish between self and non-self cells and tissues--ultimately depends on the presence of highly polymorphic gene(s). Allorecognition loci are the most diverse ever described, with tens to hundreds of alleles observed in a population.
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Allorecognition in compound ascidians.
The International journal of developmental biology, 1995In botryllids (colonial ascidians), there are two types of allorecognition: colony specificity and colony resorption. Colony specificity is manifested by fusion and rejection between two conspecific colonies. The genetic basis for this colony specificity resides in a single highly polymorphic gene locus (fusibility locus) with codominantly expressed ...
Y, Saito, E, Hirose, H, Watanabe
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T-cell allorecognition of HLA class II
Human Immunology, 1990The present review is meant to summarize and discuss the data available for the T-cell allorecognition of HLA class II. It is shown that the majority of T-cell reactions correlate with the presence of polymorphic sequences on the MHC molecule. The most simple explanation for such reactions would be that the T cells recognize the polymorphic part of the
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The Evolution of Allorecognition Specificity
1988Intraspecific aggression between clonal cnidarians is not random with respect to genotype; instead, agonistic behavior is modified according to the relatedness of contestants such that clonemates and close relatives behave passively, whereas more distant relatives behave aggressively.
Richard K. Grosberg, James F. Quinn
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MECHANISMS OF INDIRECT ALLORECOGNITION
Transplantation, 1998Ana Maria Waaga +6 more
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