Results 191 to 200 of about 67,162 (289)

Unveiling the molecular basis of lobeline's allosteric regulation of NMDAR: insights from molecular modeling. [PDF]

Sci Rep, 2023
Remya C, Variyar EJ, Omkumar RV, Sadasivan C, Dileep KV.   +4 more
europepmc   +1 more source

Allosteric regulation of a ribozyme activity through ligand-induced conformational change [PDF]

, 1998
Michihiro Araki, Yasushi Okuno, Yukari Hara, Y. SUGIURA   +3 more
openalex   +1 more source

Pharmacological Inhibition of APT2 by Solasonine Promotes Ferroptosis Through Palmitoylation Modulation in Gallbladder Cancer

Phytotherapy Research, EarlyView.
Schematic illustration of SS‐induced ferroptosis through targeting APT2‐mediated STAT3 palmitoylation in GBC cells. ABSTRACT Gallbladder cancer (GBC), the most prevalent and lethal biliary tract malignancy, lacks effective therapeutic strategies. Solasonine (SS), a bioactive steroidal alkaloid derived from Solanum nigrum L, exhibits antitumor activity ...
Liu‐qing Shi, Jing‐wei Zhao, Jia‐yun Zhu, Cheng Zhao, Zi‐yi Yang, Li‐jia Pan, Ben Ma, Zheng‐yu Chen, Zi‐ying Wang, Chun‐jie Li, Shi‐lei Liu, Jia‐wei Mei, Ping Dong   +12 more
wiley   +1 more source

Crystal Structures of the Global Regulator DasR from Streptomyces coelicolor: Implications for the Allosteric Regulation of GntR/HutC Repressors

, 2016
S.B. Fillenberg, Mario D. Friess, С. Körner, Rainer A. Böckmann, Yves A. Muller   +4 more
openalex   +1 more source

Flexoelectric Polarization‐Enhanced Gd‐Based Nanoflowers for Efficient Phosphatase‐Mimicking Dephosphorylation

Small Structures, EarlyView.
Flexoelectric polarization is harnessed to dynamically enhance phosphatase‐mimicking catalysis in Gd‐based nanoflowers, enabling ultrasound‐responsive and efficient biophosphate ester hydrolysis through strain‐induced electronic modulation. Phosphatase‐mimicking nanozymes provide highly stable enzyme‐like activity but remain limited by their static ...
Linjing Su, Jingyan Xu, Rong Huang, Jinlan Liao, Lixue Zhao, Ling Li, Zhi Zhang, Yuhao Xiong   +7 more
wiley   +1 more source

Author response: Domain coupling in allosteric regulation of SthK measured using time-resolved transition metal ion FRET

Pierce Eggan, Sharona E. Gordon, William N. Zagotta   +2 more
openalex   +1 more source

A Longitudinal Assessment of Endometriosis Patients Prescribed Cannabis‐Based Medicinal Products: A Case Series From the UK Medical Cannabis Registry

Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT Background Although there is growing evidence supporting the use of cannabis‐based medicinal products (CBMPs) for the management of chronic pain, there is a paucity of data on their effect on endometriosis‐associated chronic pain. Aims This study aimed to perform an analysis of pain‐specific and general health‐related quality of life (HRQoL ...
Sara Getter, Simon Erridge, John Warner‐Levy, Evonne Clarke, Katy McLachlan, Ross Coomber, Shelley Barnes, Alia Darweish Medniuk, Rahul Guru, Wendy Holden, Mohammed Sajad, Robert Searle, Azfer Usmani, Sanjay Varma, James J. Rucker, Michael Platt, Mikael H. Sodergren   +16 more
wiley   +1 more source

Intradomain Allosteric Regulation of Soluble Epoxide Hydrolase by Its Substrates. [PDF]

Int J Mol Sci
Matsumura S, Shida A, Tsuchii M, Wada M, Charneau J, Tsuji M, Hasumi K, Suzuki E.   +7 more
europepmc   +1 more source

Supplementary Data from Allosteric Regulation of Switch-II Domain Controls KRAS Oncogenicity

Moon Hee Yang, Timothy H. Tran, Bethany Hunt, Rebecca Agnor, Christian W. Johnson, Bing Shui, Timothy J. Waybright, Jonathan A. Nowak, Andrew G. Stephen, Dhirendra K. Simanshu, Kevin M. Haigis   +10 more
openalex   +1 more source

A Solution NMR and Crystallographic Study of the Role of the Quaternary Shift in the Allosteric Regulation of Phosphofructokinase from B. stearothermophilus [PDF]

, 2009
Rockann Mosser, Manchi Reddy, James C. Sacchettini, Tatyana I. Igumenova, Gregory D. Reinhart   +4 more
openalex   +1 more source