Results 191 to 200 of about 130,472 (328)

Allosteric regulation of fibronectin binding by the anti-β1 integrin antibody TS2/16. [PDF]

PNAS Nexus
Ding J, Fantini DA, Dedden D, Schumacher S, Biertümpfel C, Mizuno N.   +5 more
europepmc   +1 more source

Structural basis for the allosteric regulation and dynamic assembly of DNMT3B. [PDF]

Nucleic Acids Res, 2023
Lu J, Fang J, Zhu H, Liang KL, Khudaverdyan N, Song J.   +5 more
europepmc   +1 more source

FimH Forms Catch Bonds That Are Enhanced by Mechanical Force Due to Allosteric Regulation [PDF]

, 2008
Olga Yakovenko, Shivani Sharma, Manu Forero-Shelton, Veronika Tchesnokova, Pavel Aprikian, Brian Kidd, Albert J. Mach, Viola Vogel, Evgeni V. Sokurenko, Wendy E. Thomas   +9 more
openalex   +1 more source

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

ChemistryOpen, EarlyView.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel, Mohammed Al‐zharani, Lina M. Alneghery, Noha A. Ahmed, Faris F. Aba Alkhayl, Al Mokhtar Lamsabhi   +5 more
wiley   +1 more source

Allosteric regulation of prostaglandin endoperoxide H₂ synthases. [PDF]

J Biol Chem
Dong L, Malkowski MG.
europepmc   +1 more source

Identification of a Target Site in Plasminogen Activator Inhibitor-1 That Allows Neutralization of Its Inhibitory Properties Concomitant with an Allosteric Up-regulation of Its Antiadhesive Properties [PDF]

, 2001
Thu-Hoa Ngo, Marc Hoylaerts, Isabelle Knockaert, Els Brouwers, Paul Declerck   +4 more
openalex   +1 more source

Data from: Biochemical, structural and dynamical characterizations of the lactate dehydrogenase from Selenomonas ruminantium provide information about an intermediate evolutionary step prior to complete allosteric regulation acquisition in the super family of lactate and malate dehydrogenases.

, 2023
Quentin Bertrand, Sandrine Coquille, Antonio Iorio, Fabio Sterpone, Dominique Madren   +4 more
openalex   +1 more source

Enzyme Regulation: Allosteric Cosmos [PDF]

Nature, 1970
openaire   +1 more source

Structural mechanisms of allosteric regulation in the human cis-prenyltransferase complex. [PDF]

Nat Commun
Giladi M, Kredi S, Guardiani C, Aviram L, Vaňková P, Gaizinger Y, Man P, Giacomello A, Haitin Y.   +8 more
europepmc   +1 more source

Biophysical Mechanism of Allosteric Regulation of Actin Capping Protein. [PDF]

J Mol Biol, 2023
Mooren OL, Stuchell-Brereton MD, McConnell P, Yan C, Wilkerson EM, Goldfarb D, Cooper JA, Sept D, Soranno A.   +8 more
europepmc   +1 more source