Results 191 to 200 of about 127,473 (347)

Allosteric regulation of Senecavirus A 3Cpro proteolytic activity by an endogenous phospholipid. [PDF]

PLoS Pathog, 2023
Zhao HF, Meng L, Geng Z, Gao ZQ, Dong YH, Wang HW, Zhang H.   +6 more
europepmc   +1 more source

Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis [PDF]

, 2005
Jill D. Dombrauckas, Bernard D. Santarsiero, Andrew D. Mesecar   +2 more
openalex   +1 more source

Allosteric Regulation of Glutamate Dehydrogenase [PDF]

Biophysical Journal, 2020
Zoe A. Hoffpauir, Thomas J. Smith, Hong Q. Smith, Eleena Sherman   +3 more
openaire   +2 more sources

Feasibility of Treating Eosinophilic Chronic Rhinosinusitis Using Short‐Chain Fatty Acids

The Laryngoscope, EarlyView.
Epithelial cell‐derived cytokines including thymic stromal lymphopoietin (TSLP) are important in the pathogenesis of chronic rhinosinusitis with nasal polyps. We demonstrate the inhibitory effect of TSLP production in airway epithelial cells and eosinophil survival by short‐chain fatty acids (SCFAs) as a potential new strategy to reduce nasal polyps ...
Rikako Gozawa, Yoshimasa Imoto, Yuki Sonoda, Ayako Maegawa, Anna Shimizu, Masanori Kidoguchi, Keisuke Koyama, Naoto Adachi, Taiyo Morikawa, Yuto Miyazaki, Kyoko Saito, Masafumi Sakashita, Shigeharu Fujieda   +12 more
wiley   +1 more source

Unveiling the molecular basis of lobeline's allosteric regulation of NMDAR: insights from molecular modeling. [PDF]

Sci Rep, 2023
Remya C, Variyar EJ, Omkumar RV, Sadasivan C, Dileep KV.   +4 more
europepmc   +1 more source

Ligand-specific allosteric regulation of coactivator functions of androgen receptor in prostate cancer cells [PDF]

, 2006
Sung Hee Baek, Kenneth A. Ohgi, Charles A. Nelson, Derek S. Welsbie, Charlie Chen, Charles L. Sawyers, David W. Rose, Michael G. Rosenfeld   +7 more
openalex   +1 more source

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu, Zexin Zhu, Lauren Fields, Hua Zhang, Lingjun Li   +4 more
wiley   +1 more source

Molecular‐Informed Network Analysis Unveils Fatigue‐Related Functional Connectivity in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Fatigue in Parkinson's disease (PD) is a prevalent and debilitating non‐motor symptom. Despite its significant impact on quality of life, the underlying neurochemical and network‐based mechanisms remain poorly understood. Objectives This observational study applied a multimodal imaging approach to explore potential links between the
Ilaria Antonella Di Vico, Manuela Moretto, Agnese Tamanti, Giovanni Tomelleri, Giulia Burati, Daniel Martins, Ottavia Dipasquale, Mattia Veronese, Alessandra Bertoldo, Elisa Menini, Angela Sandri, Sarah Ottaviani, Francesca Benedetta Pizzini, Michele Tinazzi, Marco Castellaro   +14 more
wiley   +1 more source

Allosteric regulation of L-lactate dehydrogenase: Beyond effector-mediated tetramerization. [PDF]

Protein Sci
Cai H, Shulami S, Štefanić Z, Hrenar T, Maršavelski A, Fishman A.   +5 more
europepmc   +1 more source

Allosteric Regulation of Glycogen Phosphorylase by Order/Disorder Transition of the 250' and 280s Loops. [PDF]

Biochemistry, 2023
Kish M, Subramanian S, Smith V, Lethbridge N, Cole L, Vollmer F, Bond NJ, Phillips JJ.   +7 more
europepmc   +1 more source