Results 201 to 210 of about 63,430 (242)

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Proteolytic stabilization of a spider venom peptide results in an orally active bioinsecticide

Pest Management Science, EarlyView.
Selective editing out of an insect gut protease cleavage site renders a spider‐derived insecticidal peptide active by ingestion by insect pests. Abstract BACKGROUND The toxin peptide U1‐AGTX‐Ta1b from the Hobo spider, Eratigena agrestis (Walckenaer, 1802), was studied to determine its potential to serve as a bioinsecticide.
Breck R. Davis, Alexandra M. Haase, Joseph S. Tourtois, Daniel L. Hulbert, Rachel E. Cornell, Brian T. DeVree, Cadence J. Flohrschutz, Lucille M. Bell, Daniel C. Peck, Trang T. Nguyen, Lin Bao, Robert M. Kennedy, Kyle D. Schneider   +12 more
wiley   +1 more source

Cryo-EM structures of the human NaS1 and NaDC1 transporters revealed the elevator transport and allosteric regulation mechanism. [PDF]

Sci Adv
Chi X, Chen Y, Li Y, Dai L, Zhang Y, Shen Y, Chen Y, Shi T, Yang H, Wang Z, Yan R.   +10 more
europepmc   +1 more source

Ligand Recognition and Function of TAARs

Sensory Neuroscience, EarlyView.
The trace amine‐associated receptor (TAAR) family represents a highly conserved group of G protein‐coupled receptors (GPCRs) in vertebrates. TAARs specifically bind to different amine ligands and mediate a variety of physiological and behavioral processes.
Kang‐Ying Qian, Yue Hao, Zheng Wang, Qian Li   +3 more
wiley   +1 more source

Structural Basis for Morpheein-type Allosteric Regulation of Escherichia coli Glucosamine-6-phosphate Synthase

, 2012
Stéphane Mouilleron, Marie‐Ange Badet‐Denisot, Ludovic Pecqueur, Karine Madiona, Nadine Assrir, Bernard Badet, Béatrice Golinelli‐Pimpaneau   +6 more
openalex   +1 more source

Tailored Metal‐Organic Framework‐Based Enzyme Hybrids: Immobilization Strategies, Improved Performance, and Biological Applications

Small Science, EarlyView.
Metal‐organic frameworks (MOFs) offer versatile platforms for enzyme immobilization to overcome their inherent fragility. However, challenges such as restricted conformation and mass transfer limitations remain. Advances in precise MOF design can help overcome these obstacles, expanding their applicability across diverse fields, highlighting the ...
Xiang Xu, Jiacheng Wan, Jun Sun, Lina Wu, Jianping Lei   +4 more
wiley   +1 more source

Structure of an Engineered β-Lactamase Maltose Binding Protein Fusion Protein: Insights into Heterotropic Allosteric Regulation

, 2012
Ke Wei, Abigail H. Laurent, Morgan D. Armstrong, Yuchao Chen, William E. Smith, Jing Liang, Chapman Wright, Marc Ostermeier, Focco van den Akker   +8 more
openalex   +2 more sources

Design, Mechanisms, and Applications of DNA‐Mediated Dynamically Reconfigurable Plasmonic Gold Nanostructures

Small Methods, EarlyView.
This review provides key principles of designing and synthesizing reconfigurable plasmonic gold nanostructures for generating and controlling physical, chemical, and biological properties and functions. The recent advances in the biological and materials applications of dynamically reconfigurable plasmonic gold nanostructures are also summarized ...
So Young Choi, Jieun Kim, Eun Ho Song, Eunhye Park, Jingrui Wu, Juyeon Yoo, Jwa‐Min Nam   +6 more
wiley   +1 more source

Nanozymes in Reactive Oxygen Species‐Dependent Diseases: From Design and Preclinical Studies to Clinical Translation Prospects

Small Structures, EarlyView.
Nanozymes emerge as promising therapeutic agents for reactive oxygen species (ROS)‐dependent diseases, offering advantages over traditional biocatalysts through enhanced stability, tunability, and targeting capabilities. This review explores their mechanisms, design strategies, and clinical progress, emphasizing precision medicine potential.
Lihong Zhou, Jingyu Yan, Chenying Cui, Yurong Xu, Kaifang Zhang, Meijun Du, Zhuowei Zhang, Xiuping Wu, Bing Li   +8 more
wiley   +1 more source

Autonomous Artificial Molecular Motors and Pumps

ChemSystemsChem, EarlyView.
Autonomous energy consumption is the only way to introduce molecular motors into more sophisticated, larger systems, capable of life‐like behavior. We reviewed a selection of the most recent advances in the field molecular motors focusing on those capable of performing continuous and autonomous motion under constant experimental conditions, that is ...
Chiara Taticchi, Massimiliano Curcio, Stefano Corra   +2 more
wiley   +1 more source