Results 201 to 210 of about 130,849 (328)

A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation. [PDF]

Nat Commun
Nguyen BV, Özden C, Dong K, Koc OC, Torres-Ocampo AP, Dziedzic N, Flaherty D, Huang J, Sankara S, Abromson NL, Tomchick DR, Fissore RA, Chen J, Garman SC, Stratton MM.   +14 more
europepmc   +1 more source

Supplementary Data from Allosteric Regulation of Switch-II Domain Controls KRAS Oncogenicity

Moon Hee Yang, Timothy H. Tran, Bethany Hunt, Rebecca Agnor, Christian W. Johnson, Bing Shui, Timothy J. Waybright, Jonathan A. Nowak, Andrew G. Stephen, Dhirendra K. Simanshu, Kevin M. Haigis   +10 more
openalex   +1 more source

High Km soluble 5′-nucleotidase from human placenta. Properties and allosteric regulation by IMP and ATP.

, 1988
Jarosław Spychała, Vicente Madrid‐Marina, I. H. Fox   +2 more
openalex   +1 more source

Vanillin Modulates the Sedative Effect of Diazepam, Possibly Through GABAergic Interaction Pathways in Thiopental Sodium‐Induced Sleeping Mice

Food Safety and Health, EarlyView.
Vanillin showed moderate sedative and modulatory synergistic activities on diazepam in thiopental sodium‐induced sleeping mice. These effects are implicated with GABAergic intervention. ABSTRACT Insomnia is a common sleep disorder affecting approximately 10% of adults.
Salehin Sheikh, Md. Shimul Bhuia, Raihan Chowdhury, Md. Sakib Al Hasan, Most. Israt Jahan Oni, Imam Hossen Rakib, Mir Imran Alim, Jakia Sultana, Muhammad Torequl Islam   +8 more
wiley   +1 more source

Allosteric regulation of BH3-in-groove interactions by tail anchors of BCL-xL complexes limits BH3 mimetic antagonism. [PDF]

Nat Commun
Maillet L, Fétiveau A, Lalier L, Martin N, Barillé-Nion S, Guette C, Gautier F, Téletchéa S, Juin PP.   +8 more
europepmc   +1 more source

Allosteric regulation and inhibition of protein kinases. [PDF]

Biochem Soc Trans, 2023
Mingione VR, Paung Y, Outhwaite IR, Seeliger MA.   +3 more
europepmc   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Allosteric regulation of the Golgi-localized PPM1H phosphatase by Rab GTPases modulates LRRK2 substrate dephosphorylation in Parkinson's disease. [PDF]

J Biol Chem
Adhikari A, Tripathi A, Chiang CY, Sherpa P, Pfeffer SR.   +4 more
europepmc   +1 more source

A Conserved Allosteric Pathway in Tyrosine Kinase Regulation [PDF]

, 2019
William M. Marsiglia, Joseph Katigbak, Sijin Zheng, Moosa Mohammadi, Yingkai Zhang, Nathaniel J. Traaseth   +5 more
openalex   +1 more source

Regulation of pyruvate dehydrogenase complex: Dancing to different drums in cancer

International Journal of Cancer, EarlyView.
Abstract Mechanisms governing the regulation of pyruvate dehydrogenase complex (PDC) are markedly modified in cancer cells compared to normal cells. PDC activity in normal cells is controlled by the reversible phosphorylation of three serine residues by dedicated kinases and phosphatases.
Mulchand S. Patel, Todd C. Rideout
wiley   +1 more source