Results 211 to 220 of about 130,849 (328)

Allosteric regulation of proteolytic machines unveiled by the synergy between cryo-EM and solution NMR spectroscopy. [PDF]

Biochem J
Turner M, Harkness RW, Ripstein ZA, Huang R, Vahidi S.   +4 more
europepmc   +1 more source

Disease-causing cystathionine β-synthase linker mutations impair allosteric regulation. [PDF]

J Biol Chem, 2023
Roman JV, Mascarenhas R, Ceric K, Ballou DP, Banerjee R.   +4 more
europepmc   +1 more source

Hormonal and Allosteric Regulation of the Luteinizing Hormone/Chorionic Gonadotropin Receptor [PDF]

А. О. Шпаков
openalex   +1 more source

Identification of a Target Site in Plasminogen Activator Inhibitor-1 That Allows Neutralization of Its Inhibitory Properties Concomitant with an Allosteric Up-regulation of Its Antiadhesive Properties [PDF]

, 2001
Thu-Hoa Ngo, Marc Hoylaerts, Isabelle Knockaert, Els Brouwers, Paul Declerck   +4 more
openalex   +1 more source

Allosteric regulation of Senecavirus A 3Cpro proteolytic activity by an endogenous phospholipid. [PDF]

PLoS Pathog, 2023
Zhao HF, Meng L, Geng Z, Gao ZQ, Dong YH, Wang HW, Zhang H.   +6 more
europepmc   +1 more source

Engineering allosteric regulation into the hinge region of a circularly permuted TEM-1 β-lactamase [PDF]

, 2010
Valéry Mathieu, Jacques Fastrez, Patrice Soumillion   +2 more
openalex   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy, Dávid Mező, Kinga K. Nagy, Viktória Perey‐Simon, Judit Tóth, Angéla Békési, Beáta Vértessy, Máté Varga   +7 more
wiley   +1 more source

ATP-Driven Allosteric Regulation of 14-3-3: Positive Modulation of ATP Hydrolysis and Negative Regulation of Peptide Binding. [PDF]

FASEB J
Bagdiya P, Soni N, Jaiswal D, Dalvi S, Kanitkar T, Madhusudhan MS, Venkatraman P.   +6 more
europepmc   +1 more source

Regulation of mitochondrial malate dehydrogenase. Evidence for an allosteric citrate-binding site.

, 1982
Thomas R. Mullinax, Johanna Mock, A. J. McEvily, John Harrison   +3 more
openalex   +1 more source

Artificial intelligence strategies for predicting kinase inhibitor resistance: A comprehensive review of methods, challenges, and future perspectives

Journal of Intelligent Medicine, EarlyView.
Abstract Kinase inhibitors are essential in targeted cancer therapy, yet resistance often emerges through secondary mutations, activation of compensatory signaling pathways, or drug‐efflux mechanisms. Artificial intelligence (AI) provides a workflow‐based strategy rather than a list of unrelated tools for predicting and addressing kinase‐inhibitor ...
Faris Hassan, Mohanad Ali Deifallah, Alaa Zaghloul, Rania Elgohary   +3 more
wiley   +1 more source