Results 231 to 240 of about 68,403 (252)
Some of the next articles are maybe not open access.
An engineered chorismate mutase with allosteric regulation
Bioorganic & Medicinal Chemistry, 2003Besides playing a central role in phenylalanine biosynthesis, the bifunctional P-protein in Eschericia coli provides a unique model system for investigating whether allosteric effects can be engineered into protein catalysts using modular regulatory elements.
Sheng, Zhang +2 more
openaire +2 more sources
Allosteric regulation of Warts
Science Signaling, 2016Hippo pathway regulators allosterically switch the conformation of the kinase Warts.
openaire +1 more source
Allosteric regulation of purine nucleoside phosphorylase
Archives of Biochemistry and Biophysics, 1991Purine nucleoside phosphorylase (EC 2.4.2.1) from bovine spleen is allosterically regulated. With the substrate inosine the enzyme displayed complex kinetics: positive cooperativity vs inosine when this substrate was close to physiological concentrations, negative cooperativity at inosine concentrations greater than 60 microM, and substrate inhibition ...
P A, Ropp, T W, Traut
openaire +2 more sources
Allosteric regulation of the cAMP receptor protein
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 2001The cyclic AMP receptor protein (CRP) of Escherichia coli is a dimer made up of identical subunits. Each CRP subunit contains a cyclic nucleotide binding pocket and the CRP dimer exhibits negative cooperativity in binding cAMP. In solutions containing cAMP, CRP undergoes sequential conformation changes from the inactive apo-form through the active CRP:(
openaire +2 more sources
Dynamic Protein Allosteric Regulation and Disease
2019Allostery is largely associated with conformational and functional transitions in individual proteins. All dynamic proteins are allosteric. This concept can be extended to consider the impact of conformational perturbations on cellular function and disease states.
Ruth, Nussinov +2 more
openaire +2 more sources
Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes
Cell, 2021Peng Xiao, Liangliang Kong, Yuan Yuan
exaly
An Allosterically Regulated Molecular Shuttle
Angewandte Chemie International Edition, 2006Dana S, Marlin +3 more
openaire +2 more sources
An Allosteric Ribozyme Regulated by Doxycyline
Angewandte Chemie, 2000Nicolas, Piganeau +3 more
openaire +2 more sources
Dissociation of Enzyme Oligomers: A Mechanism for Allosteric Regulation
Critical Reviews in Biochemistry and Molecular Biology, 1994Thomas W Traut, T W Traut
exaly