Results 231 to 240 of about 130,472 (328)

Allosteric regulation of Senecavirus A 3Cpro proteolytic activity by an endogenous phospholipid. [PDF]

PLoS Pathog, 2023
Zhao HF, Meng L, Geng Z, Gao ZQ, Dong YH, Wang HW, Zhang H.   +6 more
europepmc   +1 more source

Author response: Filamentation modulates allosteric regulation of PRPS

, 2022
Huan-Huan Hu, Guangming Lu, Chia‐Chun Chang, Yi‐Lan Li, Jiale Zhong, Chen-Jun Guo, Xian Zhou, Boqi Yin, Tianyi Zhang, Ji‐Long Liu   +9 more
openalex   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Allosteric regulation of the tyrosine phosphatase PTP1B by a protein-protein interaction. [PDF]

Protein Sci
Chartier CA, Woods VA, Xu Y, van Vlimmeren AE, Johns AC, Jovanovic M, McDermott AE, Keedy DA, Shah NH.   +8 more
europepmc   +1 more source

SpoIIIE Protein Achieves Directional DNA Translocation through Allosteric Regulation of ATPase Activity by an Accessory Domain

, 2013
Marina Besprozvannaya, Valerie Pivorunas, Zach M. Feldman, Briana M. Burton   +3 more
openalex   +1 more source

Continuous Allosteric Regulation of a Viral Packaging Motor by a Sensor that Detects the Density and Conformation of Packaged DNA [PDF]

, 2015
Zachary T. Berndsen, Nicholas Keller, Douglas E. Smith   +2 more
openalex   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Domain coupling in allosteric regulation of SthK measured using time-resolved transition metal ion FRET. [PDF]

Elife
Eggan P, Gordon SE, Zagotta WN.
europepmc   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

A Conserved Allosteric Pathway in Tyrosine Kinase Regulation [PDF]

, 2019
William M. Marsiglia, Joseph Katigbak, Sijin Zheng, Moosa Mohammadi, Yingkai Zhang, Nathaniel J. Traaseth   +5 more
openalex   +1 more source