Results 271 to 280 of about 127,473 (347)

Dynamic inter-domain transformations mediate the allosteric regulation of human 5, 10-methylenetetrahydrofolate reductase. [PDF]

Nat Commun
Blomgren LKM, Huber M, Mackinnon SR, Bürer C, Baslé A, Yue WW, Froese DS, McCorvie TJ.   +7 more
europepmc   +1 more source

Determination of thermodynamic parameters in the ATP and ADP allosteric regulation of E.coli NADP ⁺ ‐specific glutamate dehydrogenase

, 2007
David Luther Mork, Heather A Asplin, Jarod Barnes, Dennis Roden   +3 more
openalex   +1 more source

Autonomous Artificial Molecular Motors and Pumps

ChemSystemsChem, EarlyView.
Autonomous energy consumption is the only way to introduce molecular motors into more sophisticated, larger systems, capable of life‐like behavior. We reviewed a selection of the most recent advances in the field molecular motors focusing on those capable of performing continuous and autonomous motion under constant experimental conditions, that is ...
Chiara Taticchi, Massimiliano Curcio, Stefano Corra   +2 more
wiley   +1 more source

Allosteric regulation of nitrate transporter NRT via the signaling protein PII. [PDF]

Proc Natl Acad Sci U S A
Li B, Wang XQ, Li QY, Xu D, Li J, Hou WT, Chen Y, Jiang YL, Zhou CZ.   +8 more
europepmc   +1 more source

A structural basis for the allosteric regulation of non‐hydrolysing UDP‐GlcNAc 2‐epimerases

, 2008
Lucas Malard Velloso, Shyam S. Bhaskaran, Raymond Schuch, Vincent A. Fischetti, C. Erec Stebbins   +4 more
openalex   +2 more sources

The regulatory effects and applications of TIGIT/CD155 on the tumor microenvironment in HCC

VIEW, EarlyView.
Background The interaction between TIGIT and CD155 compromises immune cell efficacy in tumor targeting, potentially driving hepatocellular carcinoma (HCC) progression through diverse molecular pathways. What Was Done This study investigates the interplay between CD155 and TIGIT in regulating CD8+ T cell function and elucidates its implications in HCC ...
Wenting Li, Yukun Li, Yao Li, Mingqi Yang, Haichuan Peng, Hongwei Sun, Ping Jiang, Yizhun Zhu, Qiang Chen, Xiaobing Duan, Wei Zhao   +10 more
wiley   +1 more source

Allosteric regulation by c-di-AMP modulates a complete N-acetylglucosamine signaling cascade in Saccharopolyspora erythraea. [PDF]

Nat Commun
You D, Zhao LC, Fu Y, Peng ZY, Chen ZQ, Ye BC.   +5 more
europepmc   +1 more source

Evolution of macromolecular crystallography beamlines at the Swiss Light Source and SwissFEL

Journal of Synchrotron Radiation, EarlyView.
This review examines two decades of continuous development in macromolecular crystallography beamlines at the Swiss Light Source, along with recent contributions from SwissFEL, in the broader context of the evolution of macromolecular crystallography at synchrotron and X‐ray free‐electron laser facilities.This review highlights the development and ...
Meitian Wang
wiley   +1 more source

A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling. [PDF]

Nat Chem Biol
Lawrence RE, Shoemaker SR, Deal A, Sangwan S, Anand AA, Wang L, Marqusee S, Walter P.   +7 more
europepmc   +1 more source

Dual Inhibition of Mast Cells and Thymic Stromal Lymphopoietin Using a Novel Bispecific Antibody, CDX‐622

Allergy, EarlyView.
SCF and TSLP expression are known to drive unique immune responses leading to the onset of allergic and inflammatory diseases. Here, we describe the characterization of a novel bsAb, CDX‐622, that targets SCF and TSLP. CDX‐622 inhibits MC functions through SCF starvation and Type 2 inflammatory responses via TSLP inhibition.
Michael B. Murphy, Laura Vitale, Thomas O'Neill, Deena M. Maurer, Linda Malenchek, Andrea Crocker, Colleen Patterson, Laura Mills‐Chen, Virginia Saley, Nicole M. Antczak, James M. Boyer, Kelly M. McManus, Noe Rico Montanari, Russell A. Hammond, Joel Goldstein, Lawrence J. Thomas, Tibor Keler, Diego Alvarado   +17 more
wiley   +1 more source