Results 91 to 100 of about 656,245 (262)

Quick eVALUATION OF THE INTERVAL STABILITY OF THE LINEAR ASSIGNMENT problem SOLUTIONS

open access: yesДоклады Белорусского государственного университета информатики и радиоэлектроники, 2019
An efficient algorithm for evaluating the interval of solutions stability of opened and closed linear assignment problems based on a review of the results of optimization iterations is proposed. Economical one-step transition to the nearest vertex of the
M. P. Revotjuk   +2 more
doaj  

Dynamic Trees with Almost-Optimal Access Cost

open access: yes, 2018
info:eu-repo/semantics ...
Golin, Mordecai   +4 more
openaire   +6 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

An Almost Surely Optimal Combined Classification Rule

open access: yesJournal of Multivariate Analysis, 2002
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Construction of zero correlation zone Gaussian integer sequence set

open access: yesTongxin xuebao, 2017
The construction of zero correlation zone (ZCZ) Gaussian integer sequence set was researched.Based on binary orthogonal matrices,ZCZ ternary sequence sets were constructed by adding zeros at first.Then the ternary ZCZ squences were transformed into ...
Yu-bo LI, Jia-an SUN, Nan JING
doaj   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Izkoriščanje sončne energije na Krasu : Solar energy exploitation on Kras [PDF]

open access: yesGeodetski Vestnik, 2007
The article discusses solar energy exploitation on Kras, one of the sunniest Slovenian regions. GIS methods were used to assemble a decision tree model that provided areas most suitable for solar energy exploitation.
Klemen Zakšek   +2 more
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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