Results 111 to 120 of about 8,222,439 (341)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Jurnal Educatio: Jurnal Pendidikan Indonesia, 2018 Student learning outcomes are low and not optimal is a common problem that occurs in adolescents in almost all schools in Indonesia. One reason, teachers are less than optimal in accommodating student learning styles.
Yuyun Mashurwati
doaj +1 more source
Almost Optimal Batch-Regret Tradeoff for Batch Linear Contextual Bandits [PDF]
, 2021 Zihan Zhang, Xiangyang Ji, Yuan Zhou
openalex +1 more source
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Estimates on the Bergman Kernels in a Tangential Direction on Pseudoconvex Domains in C3
Abstract and Applied Analysis, 2018 Let Ω be a smoothly bounded pseudoconvex domain in C3 and assume that TΩreg(z0)
Sanghyun Cho
doaj +1 more source
Кардиоваскулярная терапия и профилактика, 2015 Aim. To estimate the relation of the 30-year survival equation and levels of high-density cholesterol (HDL) in almost healthy men 40-59 years old and to define based on this data the optimal level of HDL for that category of persons.Material and methods.
V. V. Belov, A. A. Menshchikov
doaj +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Optimal allocation of clusters in stepped wedge designs with a decaying correlation structure
PLoS ONE, 2023 The cluster randomized stepped wedge design is a multi-period uni-directional switch design in which all clusters start in the control condition and at the beginning of each new period a random sample of clusters crosses over to the intervention ...
Mirjam Moerbeek
doaj
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Almost automorphic solutions for fractional stochastic differential equations and its optimal control [PDF]
, 2015 C. Rajivganthi, P. Muthukumar
openalex +1 more source