α-Amanitin uptake into hepatocytes. Identification of hepatic membrane transport systems used by amatoxins [PDF]
Hepatic transport studies with amatoxins, toxic bicyclic octapeptides from poisonous mushrooms of the genus Amanita were performed, using [(6'-O,1'-N-di[3H]methyl)trp4]-alpha-amanitin and [(6'-O,1'-N-di-methyl)trp4]-[4-[3H]desmethyl)hyi3]-gamma-ama nitin.
Gerok, W. +7 more
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The Intervention and Treatment based on the Poisoning Mechanism of Alpha‑amanitin
Alpha-amanitin (AMA) are eight-amino-acid cyclic peptide with polar branches, which is produced in some specific genera of mushrooms. AMA is extremely toxic to humans, with LD50 (0.1 mg/kg). Due to AMA's special structure, it’s resistant to hot and cold.
openaire +1 more source
Production of High Purity Beta Amanitin [PDF]
Amaç: Beta amanitin nadiren bilimsel araştırmalarda kullanılmakta ve kullanımı gün geçtikçe artmaktadır. Piyasada bu ürün %90 saflıkta ticari olarak satılmaktadır. Bu araştırmada yüksek saflıkta beta amanitin üretme yöntemi tanımlanmıştır.
Kaya, Ertuğrul +5 more
core +1 more source
Improved high-performance liquid chromatographic determination with amperometric detection of alpha-amanitin in human plasma based on its voltammetric study [PDF]
A sensitive and simple method is described for the selective determination in human plasma of alpha-amanitin, the most poisonous and prevalent toxin in the lethal fungi of species Amanita, using high-performance liquid chromatography with amperometric ...
G. Bontempelli +4 more
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Unraveling Hematotoxicity of α-Amanitin in Cultured Hematopoietic Cells [PDF]
Amanita phalloides poisonings account for the majority of fatal mushroom poisonings. Recently, we identified hematotoxicity as a relevant aspect of Amanita poisonings.
de Graaf, Inge A M +18 more
core +1 more source
Alpha Kappa Alpha Sorority, Inc. Centennial Website [PDF]
The centennial website for the Alpha Kappa Alpha Sorority, Inc. Alpha Kappa Alpha Sorority, Incorporated had its humble beginnings as the vision of nine college students on the campus of Howard University in 1908.
Alpha, Alpha Kappa
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Prolonged α-amanitin treatment of cells for studying mutated polymerases causes degradation of DSIF 160 and other proteins [PDF]
A useful method for studying the function of the mammalian RNA polymerase II takes advantage of the extreme sensitivity of its largest subunit, Rpb1, to alpha-amanitin (a-amanitin).
Tsao, David Ching-heng
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Oral History Interview with Alpha Bowser [PDF]
The National Museum of the Pacific War presents an oral interview with Alpha Bowser. Bowser joined the Marine Corps and completed basic training at the Philadelphia Naval Yard in June 1933.
Bowser, Alpha
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Molecular basis of translocation, alpha-amanitin inhibition, and CPD damage recognition by RNA polymerase II [PDF]
RNA polymerase II (Pol II) is the eukaryotic enzyme responsible for transcribing all protein-coding genes into messenger RNA (mRNA). This thesis describes studies on the molecular mechanisms of Pol II translocation, alpha-amanitin inhibition and DNA ...
Brückner, Florian
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