Results 51 to 60 of about 839,892 (155)

Introns as Protective Buffers Against Transposable Elements Invasion During Genome Gigantism in a Newt

open access: yesGenes to Cells, Volume 31, Issue 2, March 2026.
In the giant Pleurodeles waltl genome, introns serve as “structural buffers,” absorbing transposable elements (TEs) to protect coding exons. While this enables “gene body inflation,” persistent TE accumulation eventually leads to transcriptional silencing and functional collapse, or “burst,” of the gene architecture.
Kazuto Bou, Kiyokazu Agata
wiley   +1 more source

STUDY ON GENES WITH ALTERED EXPRESSION IN alpha-AMANITIN POISONED MICE AND EVALUATION ON ANTAGONISTIC EFFECTS OF TRADITIONAL CHINESE MEDICINES AGAINST TOXICITY OF alpha-AMANITIN

open access: yes, 2009
The forward and reverse cDNA subtractive libraries before and after the toxic effect of alpha-amanitin were constructed by suppression subtractive hybridization and randomly selected clones from each subtractive library were screened by PCR and dot blot ...
Zhao, J, Sichuan Univ, Coll Life Sci, Minist Educ, Key LBiol Resource & Ecol Environm, Chengdu 610064, Peoples R China.   +10 more
core  

HEMOPERFUSION IN AMANITA PHALLOİDES POISONING: REPORT OF TWO CASES

open access: yesTurkish Journal of Nephrology, 2019
Amanita phalloides mushrooms are extremely toxic. Alpha-amanitin is an amatoxin known to produce deleterious effects on the liver and the kidneys, when circulating in the blood.
Osman DÖNMEZ   +2 more
doaj  

Isolable Cysteine Sulfenyl Iodide: Stabilization by a Molecular Cradle, Crystal Structure, and Biologically Relevant Reactivity

open access: yesChemBioChem, Volume 26, Issue 24, December 11, 2025.
An isolable cysteine sulfenyl iodide (Cys–SI) stabilized by a molecular cradle is reported. X‐ray analysis and reactivity studies reveal hydrolysis to sulfenic acid, electrophilic substitution with indoles, and high reactivity toward amines and dimedone, providing direct evidence for long‐standing proposals on iodine‐mediated protein modification ...
Shotaro Otaka   +4 more
wiley   +1 more source

GLS1‐RNA Polymerase II Axis Mediates Glutamine‐Dependent Hepatoprotective Effects on Alcoholic Liver Disease in High‐Protein Diets

open access: yesAdvanced Science, Volume 12, Issue 45, December 4, 2025.
GLS1 interacts with RNA polymerase II subunits, ROLR2H and POLR2E, resulting in significant suppression of RNA polymerase II activity. Importantly, the investigation demonstrates that high‐protein diets, particularly glutamine, exert protective effects against alcoholic fatty liver through GLS1‐RNA polymerase II axis.
Wenbiao Wu   +17 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +28 more
wiley   +1 more source

Notes on the founding and membership of the Alpha Rho and BKΩ chapters of AKA, undated

open access: yes, 1970
Notes narrating the history of the Alpha Rho and BKΩ chapters of Alpha Kappa Alpha, along with memberships lists from various years.Archival master image scanned in reflective mode as 48-bit RGB color TIFF using Epson 11000 XL. Display image is 8-bit 150
Alpha Kappa Alpha
core  

Affinity isolation of RNA polymerase II on amanitin-Sepharose [PDF]

open access: yes, 1984
We report here the first case of an affinity isolation of eukaryotic RNA polymerase II. The procedure employs an affinity matrix composed of [alpha]-amanitin coupled to Sepharose 4B via a ten atom spacer.
Faulstich, H.   +3 more
core   +1 more source

Thermostability of Alpha Amanitin in Water and Methanol [PDF]

open access: yesEuropean Journal of Basic Medical Sciences, 2012
Ertuğrul Kaya   +5 more
openaire   +1 more source

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