Results 31 to 40 of about 839,892 (155)

RNA is an integral component of chromatin that contributes to its structural organization.

PLoS ONE, 2007
Chromatin structure is influenced by multiples factors, such as pH, temperature, nature and concentration of counterions, post-translational modifications of histones and binding of structural non-histone proteins.
Antonio Rodríguez-Campos, Fernando Azorín   +1 more
doaj   +1 more source

Hybrid Macrocyclic Peptides — Synthetic Strategies to Diversify and Cyclize Peptide Libraries in Phage Display Selections

Chemistry – A European Journal, EarlyView.
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley   +1 more source

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

A guide to transcriptional cyclin‐dependent kinases in cancer

The FEBS Journal, EarlyView.
Transcriptional cyclin‐dependent‐kinases (tCDKs) facilitate gene expression by promoting RNA polymerase II (RNAPII) progression through discrete phases of the transcription cycle. Aberrant tCDK activity is detectable in different human cancers, thereby contributing to de‐regulated gene expression programs that drive oncogenic phenotypes.
Jennifer R. Devlin, Salla Kyheröinen, Ricky W. Johnstone   +2 more
wiley   +1 more source

Detection of alpha-amanitin encoding gene utilizing real-time PCR technique

Tạp chí Kiểm nghiệm và An toàn thực phẩm
Given the limited taxonomy of toxic fungi as well as the large number of mushroom species, identification of mycotoxins in mushroom samples can accelerate information gathering and progress, while increasing Enhanced testing accuracy of testing.
Le Vinh Hoa, Pham Van Quan, Le Thanh Long, Pham Thi Loan, Nguyen Thi Thanh Huyen   +4 more
doaj   +1 more source

Transcription and Three‐Dimensional Genome Organization: Cause, Consequence, or Coordination?

BioEssays, Volume 48, Issue 9, September 2026.
Transcription and 3D genome organization influence each other across spatial scales. Large‐scale architecture provides a relatively stable framework, while transcription and shared architectural factors refine local chromatin loops and domain boundaries. Specific long‐range interactions between regulatory elements and distal anchors can override domain‐
Dagyeong Yang, Elissa P. Lei
wiley   +1 more source

Mitochondria as the Hub of Apoptosis: A Comprehensive Insight From Mitochondria to Interactions With Other Organelles

MedComm, Volume 7, Issue 9, September 2026.
Mitochondria is the hub of apoptosis in various diseases. The disruption of mitochondrial structure (including membrane rupture, cristae remodeling, and mitochondrial membrane lipid redistribution), the imbalance of mitochondrial dynamics (including fusion and fission, autophagy), the release, disruption, and mutation of mitochondria DNA, as well as ...
Rubin Tan, Jinming Zhao, Rong Wang, Yue Shi, Zaozao Chen, Yixuan Ma, Na Li, Wenqing Duan, Duo Lin, Chunxiang Zhang   +9 more
wiley   +1 more source

Viroid‐Derived siRNAs: Minimal RNAs Driving Multiscale Perturbations of Host Regulatory Systems

WIREs RNA, Volume 17, Issue 5, September/October 2026.
Tiny circular RNAs known as viroids can profoundly reshape plant biology without encoding proteins. Through the production of regulatory small RNAs, they translate RNA structure into signals that connect molecular interactions with systemic disease outcomes.
Katia Aviña‐Padilla, Ana Belén Mendoza‐Soto, Yocssiry Elena Ochoa‐Rodríguez, Flor Citlally Alcántar‐Aguirre, Loranda Calderón‐Zamora   +4 more
wiley   +1 more source

Transdermal absorption of alpha amanitin toxin from amanita phalloides in mice [PDF]

, 2012
YÖK Tez No: 340816ÖZETFARELERDE AMANİTA PHALLOİDES TOKSİNİ ALFA AMANİTİNİNDERİDEN EMİLİMİMustafa Gani SÜRMENYüksek Lisans Tezi, Farmakoloji Anabilim DalıTez danışmanı Yrd. Doç. Dr.
Sürmen, Mustafa Gani
core   +2 more sources

Alpha Kappa Alpha EAF Awards luncheon program, July 15, 2014

, 2014
This program for the Educational Advancement Foundation (EAF) Awards luncheon given by the Alpha Kappa Alpha sorority notes the sequence of events, leaders of the EAF, and sponsors for the gathering.Archival master image scanned in reflective mode as 48 ...
Alpha Kappa Alpha
core   +1 more source